Stroke has launched a monthly podcast, Stroke Alert. Hosted by Dr. Negar Asdaghi, each episode begins by posing key takeaway questions from featured articles in the current issue of Stroke. This is followed by a brief summary and analysis of these articles, as well as an interview with the author of one of these featured articles or with one of the Stroke editors.
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On Episode 60 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the January 2026 issue of Stroke : " Impaired Perfusion and Early Ischemic Stroke Recurrence in Symptomatic Intracranial Atherosclerosis: BIORISK ICAS Study " and " Systematic Genetic Assessment in Young Patients With Cryptogenic Stroke: The ES-EASY project ." She also interviews Dr. Fabiano Cavalcante and Prof. Charles Majoie about their article " Acute Carotid Stenting for Tandem Lesions in Patients ...
On Episode 59 of the Stroke Alert Podcast, host Dr. Negar Asdaghi is joined by Dr. Eva Mistry, Stroke Associate Editor and Vice Chair of Research and Divisional Director of Vascular Neurology at the Department of Neurology and Rehabilitation Medicine at the University of Cincinnati, for the 2025 Ralph Sacco Review of Top Cerebrovascular Research. In honor of the late Dr. Ralph L. Sacco, former Editor-in-Chief of Stroke , who died in January 2023, Drs. Asdaghi and Mistry review some of the top ce...
On Episode 58 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the November 2025 issue of Stroke : " Fingolimod as a Potential Cerebroprotectant Results From the Stroke Preclinical Assessment Network " and " Apixaban and Recurrent Stroke Risk With Left Ventricular Dysfunction: A Secondary Analysis of the ARCADIA Trial ." She also interviews Drs. Aaron Rodriguez-Calienes and Santiago Ortega-Gutierrez about their article " Endovascular Thrombectomy Versus Best Medic...
On Episode 57 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the October 2025 issue of Stroke : " Oxygen Extraction Fraction on Baseline MRI Predicts Infarction Growth in Successfully Reperfused Patients " and " Tadalafil Treatment in Patients With Cerebral Small Vessel Disease: The ETLAS-2 Randomized Clinical Trial ." She also interviews Dr. Thomas Meinel on the article " Intravenous Thrombolysis in Patients With Recent Intake of Direct Oral Anticoagulants: A T...
On Episode 56 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the September 2025 issue of Stroke : " Glucagon-Like Peptide-1 Receptor Agonists and Risk of Nontraumatic Intracerebral Hemorrhage in Patients With Type 2 Diabetes " and " White Matter Hyperintensity Multispot Pattern Lesions and Cerebrovascular Amyloid Burden in Cerebral Amyloid Angiopathy ." She also interviews Dr. Cora Nijboer and Prof. Manon Benders on their article " Perinatal Arterial Stroke Trea...
On Episode 55 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the August 2025 issue of Stroke : " Anticoagulation Timing in Acute Stroke With Atrial Fibrillation According to Chronic Kidney Disease: The OPTIMAS Trial " and " Risk of Intracranial Hemorrhage With Apixaban Versus Aspirin Therapy: A Meta-Analysis of Randomized Controlled Trials ." She also interviews Dr. Stephen Ryan and Prof. Anne Aamodt about the Tenecteplase in Central Retinal Artery Occlusion Stu...
On Episode 54 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the July 2025 issue of Stroke : " Association of the Timing and Type of Acute Symptomatic Seizures With Poststroke Epilepsy and Mortality " and " Effect of Argatroban Plus Dual Antiplatelet in Branch Atherosclerosis Disease: A Randomized Clinical Trial ." She also interviews Dr. Amrou Sarraj about the article " Mechanical Thrombectomy for Large Ischemic Stroke: A Critical Appraisal of Evidence From 6 R...
Dr. Negar Asdaghi presents two key articles from the June 2025 issue of Stroke: one analyzing intensive blood pressure lowering and cerebral edema post-thrombolysis, and another on how ischemic core hypodensity affects thrombectomy in large core stroke patients. She also interviews Drs. Samantha Rivet and Felix Ng to define the no-reflow phenomenon, explore its clinical impact that can negate thrombectomy benefits, and discuss ongoing research into intra-arterial thrombolytics and other emerging therapies aimed at improving microvascular reperfusion.
On Episode 52 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the May 2025 issue of Stroke : " Assessing the Impact of the COVID-19 Pandemic on Childhood Arterial Ischemic Stroke: An Unanticipated Natural Experiment " and " Low Hemoglobin Causes Hematoma Expansion and Poor Intracerebral Hemorrhage Outcomes ." She also interviews Dr. David Fiorella about the MIND trial, presented in February at the International Stroke Conference. For the episode transcript, visit...
On Episode 51 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the April 2025 issue of Stroke : " Clinical Severity and Outcomes in Large Infarcts With Endovascular Therapy: A Post Hoc Analysis of the ANGEL-ASPECT Trial " and " Association Between Thrombus Composition and Etiology in Patients With Acute Ischemic Stroke Treated by Thrombectomy ." She also interviews Dr. Roland Veltkamp about the PRESTIGE-AF trial, presented in February at the International Stroke C...
On Episode 50 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the March 2025 issue of Stroke : " Impact of Subarachnoid Hemorrhage on Human Glymphatic Function: A Time-Evolution Magnetic Resonance Imaging Study " and " Thrombolysis for Ischemic Stroke Beyond the 4.5-Hour Window: A Meta-Analysis of Randomized Clinical Trials ." She also interviews Drs. Mayank Goyal and Michael Hill about the ESCAPE-MeVO trial, presented in February at the International Stroke Conf...
On Episode 49 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the February 2025 issue of Stroke : " Safety of Adjunctive Intraarterial Tenecteplase Following Mechanical Thrombectomy: The ALLY Pilot Trial " and " Large-Scale Plasma Proteomics Profiles for Predicting Ischemic Stroke Risk in the General Population ." She also interviews Drs. Tao Wang and Yan Ma about their article " Determining the Optimal Age for Extracranial-Intracranial Bypass Surgery: A Post Hoc...
On Episode 48 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the January 2025 issue of Stroke : " Hypoglycemic Events May Trigger Acute Ischemic Stroke Within 30 Days in Those With Diabetes: A Case-Crossover Study " and " Efficacy and Safety of a Dedicated Device for Cerebral Venous Thrombectomy: A Pilot Randomized Clinical Trial ." She also interviews Drs. Johanna Ospel and Umberto Pensato about their article " Cerebral Infarct Growth: Pathophysiology, Pragmati...
On Episode 47 of the Stroke Alert Podcast, host Dr. Negar Asdaghi is joined by Dr. Ashutosh Jadhav, Professor of Neurology and Neurosurgery at the Barrow Neurological Institute, for the 2024 Ralph Sacco Review of Top Cerebrovascular Research. In honor of the late Dr. Ralph L. Sacco, former Editor-in-Chief of Stroke , who died in January 2023, Drs. Asdaghi and Jadhav review some of the top cerebrovascular science published in any journal or presented at any scientific forum throughout the past ye...
On Episode 46 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the November 2024 issue of Stroke : " Cerebrovascular Events in Patients Undergoing Transcatheter Aortic Valve Replacement: A Review " and " Oxygen Extraction Fraction Mapping on Admission Magnetic Resonance Imaging May Predict Recovery of Hyperacute Ischemic Brain Lesions After Successful Thrombectomy: A Retrospective Observational Study ." She also interviews Drs. Mitch Wilson and Vasileios-Arsenios ...
On Episode 45 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the October 2024 issue of Stroke : " Cigarette Smoking and Observed Growth of Unruptured Intracranial Aneurysms: A Systematic Literature Review and Meta-Analysis " and " Clinical and Prognostic Characteristics of Acute BAD–Related Stroke: A Multicenter MRI–Based Prospective Study ." She also interviews Dr. Vignan Yogendrakumar about his article " Emerging Adjuvant Thrombolytic Therapies for Acute Ische...
On Episode 44 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the September 2024 issue of Stroke : " Stroke Risk After Emergency Department Treat-and-Release Visit for a Fall " and " Higher Risk of Mental Illness in Patients with Diagnosed and Untreated, Unruptured Intracranial Aneurysm: Findings from a Nationwide Cohort Study." She also interviews Dr. Yutong Chen and Professor Hugh Markus about the article " Improved Dementia Prediction in Cerebral Small Vessel ...
On Episode 43 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the August 2024 issue of Stroke : " Diagnostic Accuracy of Posterior/Anterior Periventricular WMH Ratio to Differentiate CAA From Hypertensive Arteriopathy " and " Statin Overuse in Cerebral Ischemia Without Indications: Systematic Review and Annual US Burden of Adverse Events ." She also interviews Dr. Gang Li about the article " Intensive Ambulance-Delivered Blood-Pressure Reduction in Hyperacute Str...
On Episode 42 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the July 2024 issue of Stroke : " Dual Antiplatelet Therapy After Embolic Stroke of Undetermined Source: A Subgroup Analysis of the CHANCE-2 Trial " and " Risk of Stroke in Women Using Levonorgestrel-Releasing Intrauterine Device for Contraception ." She also interviews Dr. Manabu Inoue about his article " Expanding the Treatable Imaging Profile in Patients With Large Ischemic Stroke: Subanalysis From ...
On Episode 41 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the June 2024 issue of Stroke : " Global, Regional, and National Burdens of Stroke in Children and Adolescents From 1990 to 2019: A Population-Based Study " and " Head Injury and Risk of Incident Ischemic Stroke in Community-Dwelling Adults ." She also interviews Dr. Raul Nogueira about his article " Endovascular Versus Medical Management in Distal Medium Vessel Occlusion Stroke: The DUSK Study " and h...
On Episode 40 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the May 2024 issue of Stroke : " Incidence and Outcomes of Posterior Circulation Involvement in Moyamoya Disease " and " Glymphatic System Impairment Contributes to the Formation of Brain Edema After Ischemic Stroke ." She also interviews Dr. Susanne van Veluw about her American Heart Association Centennial Collection article on " Cerebral Amyloid Angiopathy ." For the episode transcript, visit: https:...
On Episode 39 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the April 2024 issue of Stroke : " Intravenous Tirofiban Versus Alteplase Before Endovascular Treatment in Acute Ischemic Stroke: A Pooled Analysis of the DEVT and RESCUE BT Trials " and " Radial Versus Femoral Access for Mechanical Thrombectomy in Stroke Patients: A Non-Inferiority Randomized Clinical Trial ." She also interviews Dr. Shadi Yaghi about his article " Antithrombotic Treatment for Stroke ...
On Episode 38 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the March 2024 issue of Stroke : " High-Serum Brain-Derived Neurotrophic Factor Levels Are Associated With Decreased Risk of Poststroke Cognitive Impairment " and " Long-Term Risk of Arterial Thrombosis After Intracerebral Hemorrhage: MUCH-Italy ." She also interviews Drs. Santosh Murthy and Wendy Ziai about their article " Association Between Hematoma Volume and Risk of Subsequent Ischemic Stroke: A M...
On Episode 37 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the February 2024 issue of Stroke : " Intravenous Thrombolysis Before Endovascular Treatment in Posterior Circulation Occlusions: A MR CLEAN Registry Study " and " Effect of the Factor XIa Inhibitor Asundexian According to Baseline Infarct Pattern and on MRI Covert Infarct Outcomes ." She also interviews Drs. Brian Hoh and Marc Chimowitz on the Focused Update series of articles in this issue on the top...
On Episode 36 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the January 2024 issue of Stroke : " Time Window for Induced Hypertension in Acute Small Vessel Occlusive Stroke With Early Neurological Deterioration " and " Patent Foramen Ovale Management for Secondary Stroke Prevention: State-of-the-Art Appraisal of Current Evidence ." She also interviews Drs. Kelly Flemming and Issam Awad about their articles " Trial Readiness of Cavernous Malformations With Sympt...
On Episode 35 of the Stroke Alert Podcast, host Dr. Negar Asdaghi is joined by Dr. Ashkan Shoamanesh, Associate Professor of Neurology at McMaster University, for the inaugural 2023 Ralph L. Sacco Review of Top Cerebrovascular Research of the Year. In honor of the late Dr. Ralph L. Sacco, former Editor-in-Chief of Stroke , who died in January 2023, Drs. Asdaghi and Shoamanesh review some of the top cerebrovascular science published in any journal or presented at any scientific forum throughout t...
On Episode 34 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the November 2023 issue of Stroke : " Identification of Clinically Relevant Brain Endothelial Cell Biomarkers in Plasma " and " Robot-Assisted Transcranial Doppler Versus Transthoracic Echocardiography for Right to Left Shunt Detection ." She also interviews Dr. Thalia Field about her article " Study of Rivaroxaban for Cerebral Venous Thrombosis: A Randomized Controlled Feasibility Trial Comparing Anti...
On Episode 33 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the October 2023 issue of Stroke : " Spreading Depolarizations Suppress Hematoma Growth in Hyperacute Intracerebral Hemorrhage in Mice " and " Comment on the 2023 Guidelines for the Management of Patients With Aneurysmal Subarachnoid Hemorrhage ." She also interviews Dr. Rebecca Gottesman about her article " Cerebral Microbleed Patterns and Cortical Amyloid-β: The ARIC-PET Study ." For the episode tran...
On Episode 32 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the September 2023 issue of Stroke : " Prestroke and Poststroke Sulfonylurea Exposure and Functional Outcomes: A Post Hoc Analysis of the SHINE Trial " and " Sleep Duration Is Associated With Subclinical Carotid Plaque Burden ." She also interviews Dr. Alexandros Polymeris and Prof. Philippe Lyrer about their article " Tranexamic Acid for Intracerebral Hemorrhage in Patients on Non-Vitamin K Antagonist...
On Episode 31 of the Stroke Alert Podcast, host Dr. Negar Asdaghi highlights two articles from the August 2023 issue of Stroke : " Cancer Prediction With Machine Learning of Thrombi From Thrombectomy in Stroke: Multicenter Development and Validation " and " Differences in Stroke Recurrence Risk Between Atrial Fibrillation Detected on ECG and 14-Day Cardiac Monitoring ." She also interviews Dr. Robert Starke about the article " Outcome Evaluation of Repeat Stereotactic Radiosurgery for Cerebral A...
