Fake sugar Real facts

This episode we discuss the controversy around sweetners, and finally answer the age old question Shakespeare asked over 400 years ago- to sweetener or not to sweetner?? 
See below for references of studies used 

1.Effects of Sweeteners on the Gut Microbiota: A Review of Experimental Studies and Clinical Trials https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363527/
2.Artificial Sweeteners: A Systematic Review and Primer for Gastroenterologists. https://www.jnmjournal.org/journal/view.html?doi=10.5056/jnm15206
3.Association between intake of non-sugar sweeteners and health outcomes: systematic review and meta-analyses of randomised and non-randomised controlled trials and observational studies. https://www.bmj.com/content/364/bmj.k4718
4.Health outcomes of non-nutritive sweeteners: analysis of the research landscape. https://nutritionj.biomedcentral.com/articles/10.1186/s12937-017-0278-x
5.Aspartame and Risk of Cancer: A Meta-analytic Review. https://pubmed.ncbi.nlm.nih.gov/24965331/
6.Effects of Stevia Extract on Postprandial Glucose Response, Satiety and Energy Intake: A Three-Arm Crossover Trial. https://www.mdpi.com/2072-6643/11/12/3036
7.Glycemic impact of non-nutritive sweeteners: a systematic review and meta-analysis of randomized controlled trials. https://www.nature.com/articles/s41430-018-0170-6
8. Short-Term Consumption of Sucralose with, but Not without, Carbohydrate Impairs Neural and Metabolic Sensitivity to Sugar in Humans  
DOI: 10.1016/j.cmet.2020.01.014 
9. Effects of Sweeteners on the Gut Microbiota: A Review of Experimental Studies and Clinical Trials 
DOI: 10.1093/advances/nmy037 
10. Association of Low- and No-Calorie Sweetened Beverages as a Replacement for Sugar-Sweetened Beverages With Body Weight and Cardiometabolic Risk: A Systematic Review and Meta-analysis 
Doi: 10.1001/jamanetworkopen.2022.2092. 
11. The artificial sweetener erythritol and cardiovascular event risk  
Doi: 10.1038/s41591-023-02223-9 
12. Effect of eating vegetables before carbohydrates on glucose excursions in patients with type 2 diabetes 
Doi: 10.3164/jcbn.13-67 
13. Systematic review of the relationship between artificial sweetener consumption and cancer in humans: analysis of 599,741 participants  
Doi: 10.1111/ijcp.12703. 

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