Micro| Nocardia and Actinomyces (Branching Filamentous Species) - podcast episode cover

Micro| Nocardia and Actinomyces (Branching Filamentous Species)

Jan 30, 20239 minSeason 3Ep. 11
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Episode description

3.11 Nocardia and Actinomyces (Branching Filamentous Species)

Microbiology review for the USMLE Step 1 exam

  • Nocardia and Actinomyces are two gram positive bacteria that grow in filaments, resembling fungal hyphae.
  • Both are associated with chronic pulmonary lesions, subcutaneous abscesses, and multiple draining sinuses.
  • Both are capable of producing sulfur granules.
  • Actinomyces is anaerobic and colonizes the mouth, GI, and urinary tracts. It can cause "lumpy jaw syndrome" and requires a long course of high dose penicillin.
  • Nocardia is aerobic and stains weakly acid fast. It is found in the environment and typically causes cutaneous disease in immunocompetent individuals and pulmonary disease in immunocompromised individuals.
  • Treatment for Nocardia typically involves a combination of antibiotics such as sulfonamides and trimethoprim-sulfamethoxazole.
  • SNAP mnemonic: Sulfa for Nocardia; Actinomyces gets Penicillin.
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