STEM-Talk - podcast cover

STEM-Talk

Dawn Kernagis and Ken Fordwww.ihmc.us
The most interesting people in the world of science and technology
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Episodes

Episode 135: Elaine Lee discusses human performance, resilience and healthspan

Our guest today is Dr. Elaine Choung-Hee Lee, an assistant professor in the Department of Kinesiology at the University of Connecticut. Much of Elaine’s research focuses on understanding the mechanisms of resilience and investigating ways to help humans improve their stress resistance, adaptation and healthspan. Elaine’s research is focused not only on understanding fundamental biology, but also on what can be done to manipulate our biology to optimize health and performance as well as preventin...

Apr 19, 20221 hr 27 minSeason 7Ep. 135

Episode 134: Mike Griffin discusses America’s hypersonic arms race with Russia and China

Our guest today is Dr. Michael Griffin, the Pentagon’s former Undersecretary of Defense for Research and Engineering. During his two and a half years as undersecretary, Mike made hypersonic weapons and defense against them his number one priority. In today’s episode, Mike talks about the history of hypersonic technology; why he made it his number one priority at the Department of Defense; and why Russia’s and China’s growing hypersonic capability represents a serious threat to America’s national...

Mar 28, 20221 hr 13 minSeason 7Ep. 134

Episode 133: Mark Mattson talks about the benefits and science of intermittent fasting

Our guest today is Dr. Mark Mattson, who is affectionally known as the godfather of intermittent fasting. The National Institute of Health describes Mark as “one of the world’s top experts on the potential cognitive and physical health benefits of intermittent fasting.” He is considered a leader in the area of cellular and molecular mechanisms underlying neuronal plasticity and neurodegenerative disorders and has made major contributions to understanding the pathogenesis of Alzheimer’s disease, ...

Feb 23, 20221 hr 8 minSeason 7Ep. 133

Episode 132: Martin Kulldorff discusses vaccines, lockdowns, school closings and the global response to COVID-19

Our guest today describes the global response to COVID-19 as one of the biggest public-health fiascos in history. As you would expect, he gained quite a bit of notoriety for this contrarian view. Dr. Martin Kulldorff is an epidemiologist and biostatistician who has spent the past 30 years researching infectious diseases as well as the efficacy and safety of vaccines. He is internationally known for his statistical and epidemiological methods for the early detection and monitoring of infectious d...

Jan 24, 20221 hr 34 minSeason 7Ep. 132

Episode 131: Christopher Logothetis discusses advances in prostate cancer therapies

Our guest today is Dr. Christopher Logothetis, one of the nation’s foremost experts on prostate cancer. Chris has spent nearly five decades at MD Anderson in Houston developing therapies for prostate cancer as well as conducting research into the underlying biology of the disease. Aside from skin cancers, prostate cancer is the most common cancer among men, claiming a man’s life every 15 minutes in the United States, according to the Prostrate Cancer Foundation. Since the 1970s when Chris joined...

Dec 13, 20211 hr 5 minSeason 6Ep. 131

Episode 130: Josh Turknett talks about holistic approaches that help people end chronic migraines

Our guest today is Dr. Josh Turknett, the author of “The Migraine Miracle” and “Keto for Migraine,” two books that have helped thousands of people use a holistic approach to end their chronic migraines. Josh is often referred to as “public enemy number one to migraines” everywhere. He is a neurologist, musician, author, and entrepreneur. He has more than two decades of experience in the field of cognitive and behavioral neuroscience. Josh practices medicine in Atlanta at the Turknett Center for ...

Nov 04, 20211 hr 24 minSeason 6Ep. 130

Episode 129: Morley Stone talks about biomimetics and human performance augmentation

Our guest today is Dr. Morley Stone, the former Chief Technology Officer for the Air Force Research Laboratory (AFRL) and former Senior Vice President for Research at Ohio State University, who is now IHMC’s Chief Strategic Partnership Officer. Morley is recognized as an international leader in biomimetics and human performance. In today’s interview, we talk to Morley about his time as AFRL’s chief technology officer as well as his stint as the chief scientist for the Air Force’s 711th Human Per...

Oct 14, 202148 minSeason 6Ep. 129

Episode 128: Tommy Wood talks about high-fat diets and the metabolic flexibility of the human gut

In today’s episode, Dr. Tommy Wood returns for his fifth appearance on STEM-Talk. Tommy is a UK-trained physician and an assistant research professor of pediatrics at the University of Washington. He also is a visiting research scientist and a valued colleague of ours here at IHMC. Today’s interview focuses on a new paper that Tommy just had published by the American Society for Microbiology. It’s titled, “Reframing Nutritional Microbiota Studies To Reflect an Inherent Metabolic Flexibility of t...

Sep 23, 20211 hr 2 minSeason 6Ep. 128

Episode 127: From UFOs to fasting to the keto flu, Ken & Dawn answer questions

It’s time for another Ask Me Anything episode. In today’s show, Ken and Dawn tackle a wide range of listener questions about: — Protein intake on a ketogenic diet. — A new study on the efficacy and safety of MDMA-assisted therapy. — The Pentagon’s new report about UFOs. — Virta Health’s two-year pilot study that demonstrated people diagnosed with prediabetes had normalized their glucose through carbohydrate restriction. — The FDA’s controversial approval of the Biogen Alzheimer’s disease drug Ad...

Aug 25, 202146 minSeason 6Ep. 127

Episode 126: Christoffer Clemmensen discusses therapeutic strategies to correct obesity and its disorders

Our guest today is Dr. Christoffer Clemmensen, an associate professor and lead researcher at the University of Copenhagen’s Novo Nordisk Foundation Center for Basic Metabolic Research. Christoffer’s lab at the university explores pharmacological and therapeutic treatments for obesity and its related diseases and disorders. He and his colleagues focus on dissecting the neuroendocrine signals involved in coordinating appetite, food-motivated behavior, energy expenditure, glycemic control, and lipi...

Aug 04, 20211 hr 12 minSeason 6Ep. 126

Episode 125: Gary Taubes addresses common arguments used against ketogenic diets

Today we have the second part of our interview with science and health journalist Gary Taubes. In the first part of our interview, episode 124, we talked to Gary about his new book “The Case For Keto: Rethinking Weight Control and the Science and Practice of Low-Carb/High-Fat Eating.” In today’s episode, we talk in detail about a growing body of research and evidence that demonstrates the health benefits and safety of ketogenic diets. We also address why there remains stubborn resistance to low-...

Jul 14, 20211 hrSeason 6Ep. 125

Episode 124: Gary Taubes makes a case for the ketogenic diet and its metabolic benefits

Today we have journalist Gary Taubes making a repeat appearance on STEM-Talk to discuss his new book, “The Case for Keto: Rethinking Weight Control and the Science and Practice of Low-Carb/High-Fat Eating.” Our interview with Gary in 2016, episode 37, followed the release of his book, “The Case Against Sugar,” which went on to become a New York Times best seller. “The Case for Keto” is Gary’s fourth book about diet and chronic disease. Gary made national headlines in 2002 when he wrote an articl...

Jun 23, 202147 minSeason 6Ep. 124

Episode 123: Steve Chien talks about AI, Mars rovers, and the possibility of intelligent alien life

Episode 123 Steve Chien talks about AI, Mars rovers, and the possibility of intelligent alien life Today’s interview is with Dr. Steve Chien. Dr. Chien is JPL Fellow, Senior Research Scientist, and Technical Group Supervisor of the Artificial Intelligence Group and in the Mission Planning and Execution Section at the Jet Propulsion Laboratory, California Institute of Technology. In 2018, Steve and Ken were appointed to the National Security Commission on Artificial Intelligence, an independent c...

May 26, 202144 minSeason 6Ep. 123

Episode 122: James Kirkland on targeting senescent cells to reverse age-related diseases

In today’s episode, we talk about zombie cells, a term used to describe senescent cells because of their refusal to die. Our guest on this topic is Dr. James Kirkland, a geriatrics specialist and researcher at the Mayo Clinic in Rochester, Minnesota, who is known for his research into the role that senescence and senescent cells have on age-related dysfunction and chronic disease. As senescent cells build up in the body, they promote cellular aging and a host of chronic conditions related to agi...

May 06, 202156 minSeason 6Ep. 122

Episode 121: Pascal Lee on the Mars mission and our search for alien life in the galaxy

It has been nearly a month since NASA’s Perseverance rover landed on Mars. So far, the rover hasn’t detected any signs of past life on the planet. But scientists have determined that several of the rocks on Mars are chemically similar to volcanic rocks on Earth. This, of course, has caused quite a bit of buzz. So, the double-secret-selection committee decided it was a perfect time to invite the chairman of the Mars Institute onto the show to get his take on the Perseverance and the Mars Mission ...

Apr 14, 20211 hr 29 minSeason 6Ep. 121

Episode 120: Gordon Lithgow on alpha-ketoglutarate’s potential to affect healthspan and lifespan

Ever since Cell Metabolism published a study that found the naturally occurring metabolite alpha-ketoglutarate reduces inflammatory signaling as well as chronic inflammation, listeners have been asking Ken and Dawn for their take on the paper. Today, we have the author of the paper, Dr. Gordon Lithgow, as our guest on STEM-Talk. We talk with Gordon in-depth about his study and the potential of alpha-ketoglutarate to have positive effects on lifespan and healthspan. Gordon is a professor and vice...

Mar 17, 202148 minSeason 6Ep. 120

Episode 119: Gordon Lithgow talks about the biology of aging and prolonging lifespan

Episode 119: Gordon Lithgow talks about the biology of aging and prolonging lifespan Our guest today is Dr. Gordon Lithgow, a professor and vice president of Academic Affairs at the Buck Institute in Novato, California. Gordon’s research focuses on uncovering genes and small molecules that prolong lifespan through enhanced molecular stability. Because our conversation with Gordon was so extensive and fascinating, we have split his interview into two parts. In today’s part one of the interview, w...

Feb 25, 202157 minSeason 6Ep. 119

Episode 118: Julie Andersen talks about urolithin-A’s potential to prevent and treat neurodegenerative diseases

Today we have part two of our conversation with Dr. Julie Andersen, a professor at the Buck Institute who is conducting fascinating research into the metabolite compound urolithin-A. Laboratory experiments have demonstrated urolithin-A’s ability to induce mitophagy, which is a selective recycling of mitochondria by autophagy, a process that cleans defective mitochondria and becomes less efficient during aging. Julie’s research has focused on the potential of urolithin-A to prevent and treat such...

Feb 02, 202153 minSeason 6Ep. 118

Episode 117: Julie Andersen talks about her research into aging and neurodegenerative diseases

Our guest today is Dr. Julie Andersen, who is best known for her research into aging and age-related diseases. A professor at the Buck Institute Buck Institute for Research on Aging, an independent biomedical research institute that researches ways to extend the healthy years of life, Julie and her colleagues at Buck have focused on understanding the underlying age-related processes driving neurodegenerative diseases in order to identify novel therapeutics. Because our conversation with Julie wa...

Jan 12, 202150 minSeason 6Ep. 117

Episode 116: Marcas Bamman on the many benefits of exercise and strength training

Our guest today is Dr. Marcas Bamman, an internationally recognized researcher known for his scientific contributions to the biology of human skeletal muscle and medical rehabilitation. Marcas recently joined IHMC as a Senior Research Scientist . He is the founder and former director of the University of Alabama at Birmingham Center for Exercise Medicine. Marcas and the UAB center are recognized as world leaders in the biological mechanisms underlying exercise-induced adaptations and their clini...

Dec 16, 20201 hr 40 minSeason 5Ep. 116

Episode 115: Ken and Dawn answer listener questions about ketogenic diets, Viagra, methylene blue, fasting, Mars and more

It’s that time again for another Ask Me Anything episode. And we must say, listeners sent us a wealth of excellent questions for this round of Ask Me Anything. In today’s podcast, Ken and Dawn answer questions that range from blood-flow restriction to swimming induced pulmonary edema to intermittent fasting to methylene blue to low-carb diets, and much, much more. If you have questions you want to send to Ken and Dawn for an Ask Me Anything episode, email your question to STEM-Talk Producer Rand...

Nov 24, 20201 hr 4 minSeason 5Ep. 115

Episode 114: Lilianne Mujica-Parodi talks about how diet and ketones affect brain aging

Our guest today is Dr. Lilianne Mujica Parodi, the director of the Laboratory for Computational Neurodiagnostics at Stony Brook University. We will be talking to Lily about her paper in PNAS last year that revealed neurobiological changes associated with aging can be seen in a person’s late 40s, a much younger age than what was previously thought. She and her colleagues at Stony Brook also found that this process may be prevented or even reversed based on dietary changes that involve minimizing ...

Oct 28, 20201 hr 22 minSeason 5Ep. 114

Episode 113: Peter Pirolli discusses information foraging, AI and the future of human interaction with technology

Today’s interview features Dr. Peter Pirolli, a colleague and senior research scientist here at IHMC since 2017. He previously was a fellow at the Palo Alto Research Center (PARC) and is known for his research into human information interaction. Peter’s work on information foraging theory led to his book “ Information Foraging Theory: Adaptive Interaction with Information. ” Peter received his doctorate in cognitive psychology from Carnegie Mellon University in 1985 and throughout his career his...

Oct 08, 20201 hr 18 minSeason 5Ep. 113

Episode 112: Tim Broderick discusses biotechnology and increasing the biological aptitude and careers of elite special forces

Our guest today is Dr. Tim Broderick, the chief science officer here at IHMC . Tim is a surgeon and biomedical scientist who joined IHMC last year. Tim has had a fascinating career as a researcher, surgeon and aquanaut. He is well-known as a pioneer in laparoscopic, robotic and telerobotic surgery. He also has led multiple ground, flight and undersea-based biomedical research projects. As a result, he is an honorary NASA flight surgeon and a NOAA undersea saturation diver. Tim spent four years a...

Sep 15, 20201 hr 22 minSeason 5Ep. 112

Episode 111: Tommy Wood talks about lifestyle approaches to improve health span and lifespan

Today we have the second of our two-part interview with Dr. Tommy Wood. Ken and Dawn talk to Tommy about his ongoing research into lifestyle approaches that can improve people’s health span, lifespan and physical performance. Tommy also talks about the physiological and metabolic responses to brain injury and how these injuries can have long-term effects on brain health. In part one of our interview, episode 110, Tommy shared his thoughts on the research he has done on the importance of metaboli...

Aug 27, 20201 hr 17 minSeason 5Ep. 111

Episode 110 : Tommy Wood talks about nourishing developing brains and the importance of metabolic health

Dr. Tommy Wood is a UK-trained physician who is making his third appearance on STEM-Talk. Earlier this year before the COVID-19 outbreak, Tommy gave a well-attended lecture at IHMC about the latest research on building and preserving brain health across people’s lifespans. The lecture was so popular we invited Tommy to join us for another STEM-Talk interview. Tommy is a research assistant professor of pediatrics in the University of Washington Division of Neonatology. He was our guest on episode...

Aug 04, 20201 hr 17 minSeason 5Ep. 110

Episode 109: Robb Wolf discusses whether eating meat is bad for you and the environment … and his new book “Sacred Cow”

Today’s guest is Robb Wolf, who is making his third appearance on STEM-Talk. He has a new book, which is being released today, the same day as our interview with Robb goes live. His new book, “Sacred Cow: Why Well Raised Meat Is Good For You and Good For The Planet,” takes a critical look at the assumptions and also the misinformation about meat and provides contrarian views that are science-based showing that meat and animal fat are essential for our bodies. Robb is a former research biochemist...

Jul 14, 20201 hr 46 minSeason 5Ep. 109

Episode 108: Ken and Dawn tackle questions ranging from AI to amino acids to methylene blue to ketosis to COVID-19

Because of the number of questions that keep pouring in, today we have another Ask Me Anything episode. We also have been receiving requests to do more of these shows, so we plan to record more frequent AMA episodes in the future. If you have questions for Ken and Dawn, email them to STEM-Talk producer Randy Hammer at rhammer@ihmc.us . In today’s episode we touch a little bit on COVID-19, but most questions revolve around diet and sleep and brain health. Ken also explains the meaning behind IHMC...

Jun 23, 202058 minSeason 5Ep. 108

Episode 107: Francisco Gonzalez-Lima discusses methylene blue and near-infrared light as therapies for cognitive disorders

Today we have part two of our interview with Dr. Francisco Gonzalez-Lima, a behavioral neuroscientist at The University of Texas at Austin. Francisco and his colleagues at the Gonzalez-Lima Lab are recognized as world leaders for their research on the relationship between brain energy metabolism, memory and neurobehavioral disorders. Today’s interview focuses on two interventions Francisco has explored with the aim of protecting people against neurodegeneration: low-dose methylene blue and the a...

May 26, 202059 minSeason 5Ep. 107

Episode 106: Francisco Gonzalez-Lima talks about brain metabolic mapping and Alzheimer’s

Our guest today is Dr. Francisco Gonzalez-Lima, a professor in the department of psychology, pharmacology and toxicology and the department of psychiatry at The University of Texas at Austin. He also is a professor at the university’s Institute for Neuroscience. We covered so much ground in our discussion with Francisco that we have split his interview into two parts. Today’s interview focuses on Francisco’s fascinating background as a youth and Cuban expatriate as well as his early research int...

Apr 29, 202054 minSeason 5Ep. 106
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