Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas - podcast cover

Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas

Ever wanted to know how music affects your brain, what quantum mechanics really is, or how black holes work? Do you wonder why you get emotional each time you see a certain movie, or how on earth video games are designed? Then you've come to the right place. Each week, Sean Carroll will host conversations with some of the most interesting thinkers in the world. From neuroscientists and engineers to authors and television producers, Sean and his guests talk about the biggest ideas in science, philosophy, culture and much more.
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Episodes

AMA | June 2026

Welcome to the June 2026 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreons, whittle them down to a more manageable number -- based primarily on whether I have anything interesting to say about them, not whether the questions themselves are good -- and sometimes group them together if they are about a similar topic. Enjoy! Blog post with AMA questions and transcript: htt...

Jun 01, 20263 hr 57 min

355 | Solo: Looking Quantum Mechanics in the Eyeball

One of the major obstacles to understanding quantum mechanics is the difficulty we have in simply accepting what the theory itself is telling us. The problem is that we know what the everyday world looks like -- stuff, arranged in space, evolving through time. So we can't resist the temptation to impose that picture on the quantum description, even if it's not actually there. In this solo episode I talk about what it means to take quantum mechanics at face value, and the difficult work involved ...

May 24, 20261 hr 44 minEp. 355

354 | Christian List on Free Will and Levels of Reality

Did I have any freedom in choosing this particular podcast guest? At the level of particles, fields, and the fundamental laws of physics; no. At the level of human agents navigating the world, yes. Today's guest, Christian List, is a philosopher and political scientist who has arguably done the most to articulate the "compatibilist" perspective on free will, according to which the freedom of rational agents is entirely compatible with underlying mechanistic laws. The reconciliation depends on th...

May 18, 20261 hr 27 minEp. 354

353 | Alvin Roth on the Economics of Morally Contested Markets

Economic markets are efficient ways of deciding fair prices, at least in ideal circumstances of perfect competition, information, and choice. But there is more to life than fair prices. Two people might decide on a fair price to carry out a contract killing, but society generally frowns on the idea. Many examples of morally contestable markets feature less consensus than that one: sex work, drugs, selling organs, adopting children. In his new book Moral Economics , economist Alvin Roth investiga...

May 11, 20261 hr 12 minEp. 353

AMA | May 2026

Welcome to the May 2026 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreons, whittle them down to a more manageable number -- based primarily on whether I have anything interesting to say about them, not whether the questions themselves are good -- and sometimes group them together if they are about a similar topic. Enjoy! Blog post with AMA questions and full transcript:...

May 04, 20264 hr 6 min

352 | Bing Brunton on Connecting the Connectome to the Body

The connectome is the wiring diagram of a brain, a big matrix that tells us what neurons talk to what other neurons. Understanding it is an important step to understanding how brains work, but a long way from the final answer. A big next step is understanding how neuronal circuits connect to and guide bodily behavior. Very recent work on mapping the fruit-fly connectome has brought us closer to that goal. I talk with neuroscientist Bing Brunton about the connectome, how we can study it to unders...

Apr 27, 20261 hr 14 minEp. 352

351 | Peter Singer on Maximizing Good for All Sentient Creatures

Peter Singer has been an influential philosopher for a number of decades. He was a significant early voice in animal rights, has been a leading thinker of utilitarianism, and helped inspire the effective altruism movement. In this podcast episode, we try our best to talk about all of those things -- working from metaethical questions of consequentialism vs. other approaches, to specific flavors of utilitarianism, the practical demands that ethics places on people, the rights of animals, and the ...

Apr 20, 20261 hr 16 minEp. 351

350 | J. Eric Oliver on the Self and How to Know It

We are more familiar with ourselves than with anything else in the universe, but we generally don't come very close to really understanding what our "self" is. That's not too surprising, as selves are very complicated and we are burdened by all sorts of biases. Today's guest is J. Eric Oliver, who has been teaching a popular course at the University of Chicago called " The Intelligible Self ." His academic specialty is political science, but he brings together ideas from psychology, neuroscience...

Apr 13, 20261 hr 21 minEp. 350

AMA | April 2026

Welcome to the April 2026 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreons, whittle them down to a more manageable number -- based primarily on whether I have anything interesting to say about them, not whether the questions themselves are good -- and sometimes group them together if they are about a similar topic. Enjoy! Henson Shaving is offering 100 blades free with...

Apr 05, 20263 hr 47 min

349 | Daniel Harlow on What Quantum Gravity Teaches Us About Quantum Mechanics

There is something special about gravity. After decades of effort, there is still no convergence on the right way to reconcile Einstein's theory of general relativity with the framework of quantum mechanics. But a number of intriguing ideas have arisen along the way, including black hole radiation, the wave function of the universe, the AdS/CFT correspondence, and the role of quantum information theory. Theoretical physicist Daniel Harlow has made significant contributions to our understanding o...

Mar 30, 20261 hr 26 minEp. 349

348 | Jessica Riskin on Jean-Baptiste Lamarck and Life as Creative Agency

"Lamarkism" is a term often attached to a seemingly discredited idea in evolutionary biology: that one organism could acquire characteristics (e.g., becoming stronger through exercise) that would then be inherited by its descendants. This is a different story than the one ultimately told by the modern synthesis of evolutionary biology, according to which inheritance passes through our genome (which doesn't know that we've been working out). In her book The Power of Life: The Invention of Biology...

Mar 23, 20261 hr 15 minEp. 348

347 | Andrew Guthrie Ferguson on How Your Data Will Be Used Against You

In the 18th century, philosopher Jeremy Bentham suggested the Panopticon as a model of a prison where inmates could be constantly observed by just a single prison guard. Although his original idea was never built, the word has come to indicate any system of social control through constant surveillance. Nowadays, we are close to creating such a system, not for prisons, but for our everyday lives. The data about our whereabouts and doings is collected by our smart devices, and available for search...

Mar 16, 20261 hr 9 minEp. 347

346 | Erica Cartmill on How Human and Animal Minds Think and Play

Intelligence is a many splendored thing, especially when it comes to comparisons between species. Chimpanzees are better than humans at some numerical tasks, but less good at understanding what numbers actually mean. One window on the ways that species differ is how they play amongst themselves. I talk with anthropologist and cognitive scientist Erica Cartmill about modes of play and other social behaviors among various species, and what they reveal about the ways we all think. Upgrade your deni...

Mar 09, 20261 hr 28 minEp. 346

AMA | March 2026

Welcome to the March 2026 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreons, whittle them down to a more manageable number -- based primarily on whether I have anything interesting to say about them, not whether the questions themselves are good -- and sometimes group them together if they are about a similar topic. Enjoy! Get twenty percent off your first purchase at F...

Mar 02, 20263 hr 53 min

345 | Adam Elga on Being Rational in a Very Large Universe

Behaving rationally involves facing up to conditions of uncertainty; we never navigate the world with perfect confidence. Sometimes we are uncertain about the way the world is, but we can also be uncertain about our place within the world. This kind of situation arises in cosmology (where the relevant world can extend very far in space or time), and also in quantum mechanics (where new worlds might be created at any measurement), but also when we are simply unsure about the future history of hum...

Feb 23, 20261 hr 35 minEp. 345

344 | Adam Gurri on Liberal Democracy and How to Fight For It

It's possible to look at the course of history over the past few centuries and discern a movement toward increasing democracy, freedom, and individual rights -- "liberalism," in the political-philosophy sense of the term. But such movement isn't inevitable or irreversible, and in very recent times there have been both intellectual arguments explicitly pushing back against the liberal consensus, and political movements that are more openly nativist and authoritarian. I talk with Adam Gurri, the e...

Feb 16, 20261 hr 21 minEp. 344

343 | Tom Griffiths on The Laws of Thought

For all that human beings spend a lot of their time thinking, it's far from obvious what that process actually entails. Part of it amounts to classical logical reasoning. But an even bigger part involves reasoning with probability and uncertainty. And some of it is governed by unavoidable limitations on time and accuracy. Psychologist and computer scientist Tom Griffiths suggests that we have thought about it enough to feel that we have come to understand some general principles, which he explai...

Feb 09, 20261 hr 19 minEp. 343

AMA | Feb 2026

Welcome to the February 2026 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreons, whittle them down to a more manageable number -- based primarily on whether I have anything interesting to say about them, not whether the questions themselves are good -- and sometimes group them together if they are about a similar topic. Enjoy! Blog post with AMA questions and transcript:...

Feb 02, 20263 hr 10 min

342 | Rachell Powell on Evolutionary Convergence, Morality, and Mind

Evolution with natural selection involves an intricate mix of the random and the driven. Mutations are essentially random, while selection pressures work to prefer certain outcomes over others. There is tremendous divergence of species over time, but also repeated convergence to forms and mechanisms that are unmistakably useful. We see this clearly in eyes and fins, but the basic pattern also holds for brains and forms of social organization. I talk with philosopher Rachell Powell about what the...

Jan 26, 20261 hr 37 minEp. 342

341 | Stewart Brand on Maintenance as an Organizing Principle

"Things fall apart; the centre cannot hold," wrote W.B. Yeats. I don't know about the centre, but the tendency of things to fall apart is pretty universal, ultimately due to the Second Law of Thermodynamics. Anyone living in a society or involved with technology must therefore be interested in the concept of maintenance -- keeping systems working. In his book Maintenance: Of Everything, Part One , Stewart Brand looks at the challenges and rewards of this concept. Blog post with transcript: https...

Jan 19, 20261 hr 13 minEp. 341

340 | Rebecca Newberger Goldstein on What Matters and Why It Matters

At any given moment, an uncountable number of events are happening, but only some of them matter to us. What does it mean for something to matter, and more importantly, what does it mean for us to matter -- to ourselves as well as to others? The need to matter can be motivation to do great things, but it can also be a reason for people to come into conflict. Philosopher/novelist Rebecca Newberger Goldstein explores this issue in her new book The Mattering Instinct: How Our Deepest Longing Drives...

Jan 12, 20261 hr 18 minEp. 340

339 | Ned Block on Whether Consciousness Requires Biology

It's become increasingly clear that the Turing Test -- determining whether human interlocutors can tell whether a conversation is being carried out by a human or a machine -- is not a good way to think about consciousness. Modern LLMs can mimic human conversation with extraordinary verisimilitude, but most people would not judge them to be conscious. What would it take? Is it even possible for a computer program to achieve consciousness, or must consciousness be fundamentally "meat-based"? Philo...

Jan 05, 20261 hr 11 minEp. 339

Holiday Message 2025 | The Romance of the University

Time for the holiday message! Rounding off the year with a brief and casual reflection on some issue that doesn't quite rise to the level of a full solo podcast. And hopefully something uplifting. This year, I offer a short apologia for higher education in the liberal arts and sciences, focusing not on the down-to-earth economic/occupational benefits of a college degree, but on the very real ways in which such an education opens up possibilities for personal growth. I think all of us in academia...

Dec 22, 202543 min

AMA | December 2025

Welcome to the December 2025 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreons, whittle them down to a more manageable number -- based primarily on whether I have anything interesting to say about them, not whether the questions themselves are good -- and sometimes group them together if they are about a similar topic. Blog post with transcript: https://www.preposterous...

Dec 15, 20253 hr 37 min

338 | Ryan Patterson on the Physics of Neutrinos

The story goes that Wolfgang Pauli, who first proposed the existence of neutrinos, was embarrassed to have done so, as it was considered uncouth to hypothesize new particles that could not be detected. Modern physicists have no such scruples, of course, but more importantly neutrinos turn out to be very detectable, given sufficient resources and experimental technique. I talk with neutrino physicist Ryan Patterson about what current and upcoming experiments teach us about neutrinos themselves, a...

Dec 08, 20251 hr 26 minEp. 338

337 | Kevin Zollman on Game Theory, Signals, and Meaning

Game theory is a way of quantitatively describing what happens any time one thing interacts with another thing, when both things have goals and potential rewards. That's a pretty broad class of interesting events, so it is unsurprising that game theory is a useful way of thinking about everything from international relations to the evolution of peacock feathers. I talk with philosopher Kevin Zollman about what game theory is and how it gets used in biology and human interactions. We discuss how ...

Dec 01, 20251 hr 18 minEp. 337

336 | Anil Ananthaswamy on the Mathematics of Neural Nets and AI

Machine learning using neural networks has led to a remarkable leap forward in artificial intelligence, and the technological and social ramifications have been discussed at great length. To understand the origin and nature of this progress, it is useful to dig at least a little bit into the mathematical and algorithmic structures underlying these techniques. Anil Ananthaswamy takes up this challenge in his book Why Machines Learn: The Elegant Math Behind Modern AI . In this conversation we give...

Nov 24, 20251 hr 14 minEp. 336

AMA | November 2025

Welcome to the November 2025 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Patreons, whittle them down to a more manageable number -- based primarily on whether I have anything interesting to say about them, not whether the questions themselves are good -- and sometimes group them together if they are about a similar topic. Enjoy! Blog post with AMA questions and transcript:...

Nov 17, 20253 hr 34 min

335 | Andrew Jaffe on Models, Probability, and the Universe

Science has an incredibly impressive track record of uncovering nonintuitive ideas about the universe that turn out to be surprisingly accurate. It can be tempting to think of scientific discoveries as being carefully constructed atop a rock-solid foundation. In reality, scientific progress is tentative and fallible. Scientists propose models, assign them probabilities, and run tests to see whether they succeed or fail. In cosmologist Andrew Jaffe's new book, The Random Universe , he illustrates...

Nov 10, 20251 hr 18 minEp. 335

334 | Daniel Whiteson on the Physics of and by Aliens

The universe as revealed by physics is objective: it's out there, existing and behaving in ways that are completely independent of human thought. But the process by which we learn about the universe, and the language with which we talk about it, is extremely human-dependent. Does that mean that aliens would do science differently, and even think differently about physics, even if we all live in the same universe? Physicist Daniel Whiteson has teamed with cartoonist Andy Warner to investigate the...

Nov 03, 20251 hr 14 minEp. 334
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