Deciphering the Molecular Origins of Brain Disorders

During brain development, anomalies may arise which lead to serious conditions such as epilepsy, triggering seizures and requiring lifelong monitoring and medication. However, the underlying causes and the way in which these defects occur are not completely understood. Dr Katty (Jing-Qiong) Kang and colleagues at Vanderbilt University Medical Centre in the USA have conducted extensive research into the molecular mechanisms associated with developmental brain disorders, with a focus on genetic epilepsy. They propose novel therapeutic targets to effectively manage symptoms and improve clinical outcomes by targeting the root cause.