Immunology does everything, it even cures cancer!

My guest this week is Max Krummel, whose career has been truly remarkable. As a graduate student, he generated antibodies to CTLA-4, which not only helped to identify an inhibitory pathway of T cell regulation but can also be used to block that pathway. This work, which led the way to cancer immunotherapy, was featured in the recent documentary "Jim Allison: Breakthrough." To Max, these breakthroughs emphasized to him the importance of technology in driving innovation, a theme that runs through his use of fluorescent imaging, live-imaging, and immune-profiling as well as his leadership of the ImmunoX Initiative. Max talks about the need to question the scientific establishment, which he refers to as the "Masters of the Universe," and to embrace change.