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Science Changing Life

Science Changing Lifewww.scripps.edu
The award-winning Science Changing Life podcast offers an inside look into how Scripps Research scientists are solving the most pressing mysteries in human health and disease. Join hosts Lauren Fish and Melissa Suran, PhD, as they speak with world-class scientists at the forefronts of immunology, infectious disease, artificial intelligence, personalized medicine, neuroscience and much more. Science Changing Life gives listeners a glimpse into the people behind the science, their motivations, paths to discovery, and how they’re changing the world. Follow us on social media for more updates: @scrippsresearch on Twitter and Instagram @ScrippsResearchInstitute on Facebook Scripps Research on LinkedIn
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Episodes

Episode 26 – Cellular secrets to a longer life: Scripps Research Magazine

Peer into the future of healthy aging. In this episode (the first of a 5-part series), we shed new light on how our cells and organs work together to influence longevity, and how newly discovered molecules may be able to block biological degeneration. This article is taken from the Summer 2021 of our award-winning Scripps Research Magazine. Show notes: Explore the Scripps Research Magazine https://magazine.scripps.edu/

Aug 02, 20217 min

Episode 25 - Ed Ramos: Reversing diabetes with personalized nutrition

Dr. Ed Ramos is director of Digital Clinical Trials for the Scripps Research Digital Trials Center. Listen as we talk about empowering the individual with wearable health devices, the worst foods for spiking our blood sugar and the importance of lifelong flexibility. Show notes: PROGRESS study enrollment https://progress.scripps.edu/ PROGRESS study explainer video https://www.youtube.com/watch?v=UUdaMojHLuk&t=74s Ed’s bio https://www.scripps.edu/science-and-medicine/translational-institute/a...

May 10, 202120 min

Episode 24- Eric Topol & Andrew Ward: How Spike Protein Discoveries Drove Coronavirus Vaccine Design

Another special edition featuring an extended conversation between Dr. Eric Topol, Director of the Scripps Research Translational Institute, and Professor Andrew Ward in the Department of Integrative Structural and Computational Biology at Scripps Research. Listen as they talk about structural biology as a gamechanger in coronavirus research, what makes the SARS-CoV-2 spike protein crucial for vaccine design, and what the latest coronavirus mutations mean for the pandemic. Show notes: The Ward L...

Dec 23, 202036 min

Episode 23 – Daphne Lurie: Taking Care of your Mental Health

Dr. Daphne Lurie is a California-licensed clinical psychologist and Director of the Counseling and Psychological Services (CAPS) on the Scripps Research La Jolla campus. Listen as we talk about the impact of the COVID-19 pandemic on mental health trends, using mindfulness to become more efficient and ziplining in Costa Rica. Show notes: Daphne’s Scripps Research profile: https://www.scripps.edu/about/campus-resources/counseling-and-psychological-services/about-us/ Counseling and Psychological Se...

Dec 03, 202020 min

Episode 22 – Discovery in an Era of Social Distancing: Scripps Research Magazine

Stories brought to life! Today’s audio adventure comes from the Fall 2020 edition of our Scripps Research Magazine. We dive into the adaptations made by institute researchers during the COVID-19 pandemic to ensure both safety and continued scientific discovery. Show notes: Explore our Scripps Research Magazine and subscribe https://www.scripps.edu/news-and-events/connect-with-us/

Nov 16, 202010 min

Episode 21 - Kara Marshall: The Science of Bladder Control

Dr. Kara Marshall is based in the Department of Neuroscience at Scripps Research, working as a postdoctoral researcher in Professsor Ardem Patapoutian’s lab. Listen as we talk about the circuitry involved in urination, burst bladders and improv comedy. Show notes: The Patapoutian Lab https://patapoutianlab.org/ Kara’s recent discovery on bladder function https://www.nature.com/articles/s41586-020-2830-7 Deciphering how the body’s cells sense touch https://www.nature.com/articles/d41586-019-03955...

Oct 14, 202025 min

Episode 20 – Eric Topol & Dennis Burton: Antibodies, Vaccines and the Current State of COVID-19

Today’s special edition features an extended conversation between Dr. Eric Topol, Director of the Scripps Research Translational Institute, and Professor Dennis Burton, Chair of the Department of Immunology and Microbiology at Scripps Research. Listen as they talk about antibody cocktail treatments, the mystery of “longhaul” COVID-19 symptoms and how close we are to developing a coronavirus vaccine. Transcript of today's episode https://www.scripps.edu/covid-19/videos/topol-burton/index.html Dr....

Sep 01, 202045 min

Episode 19 – Amanda Roberts: Mice in Outer Space

Dr. Amanda Roberts is the Senior Scientific Director of the Mouse Behavioral Core at Scripps Research. Listen as we talk about microgravity as a model of accelerated aging, NASA’s top-secret agents and what happens to slime in space. (Image Credit: Andrew Roberts) Show notes: Amanda’s research profile: https://vivo.scripps.edu/display/RobertsAmanda Replay of the NASA launch (action around ~11 minutes in): https://www.cnbc.com/2019/07/25/spacex-livestream-watch-the-company-launch-nasa-crs-18-on-a...

Jul 09, 202027 min

Episode 18 - Biodiversity beyond the horizon: Scripps Research Magazine

Research discoveries brought to life! In today’s segment, we explore Scripps Research’s Natural Products Discovery Center, a historic natural collection that may hold the key to thousands of future therapies. This article is taken from the Fall 2019 edition of our Scripps Research Magazine. Show notes: Digital version of our Fall 2019 magazine: https://issuu.com/endeavor-scripps-research/docs/magazine_fall2019_pageflipper?embed_cta=read_more&embed_context=embed&embed_domain=www.scripps.e...

Feb 18, 202011 min

Episode 17 - Time is ticking against Lyme: Scripps Research Magazine

Research discoveries brought to life! In today’s short story, we find out how medicines designed for our pets are now being repurposed by our scientists to provide a lasting, protective vaccine against Lyme disease. This article is taken from the Fall 2019 edition of our Scripps Research Magazine. Show notes: Digital version of the Scripps Research Fall 2019 magazine: https://www.scripps.edu/news-and-events/connect-with-us/magazine-current-issue/index.html Subscribe to receive the Scripps Resear...

Jan 13, 20204 min

Episode 16 – David Biello: What Makes a Great Science TED Talk

David Biello is an award-winning journalist and the scientific curator for TED. Listen as we talk about his favorite areas of science, how to craft a compelling narrative and being obsessed with blind cavefish. Show notes: David’s profile at TED (and book link) https://www.ted.com/speakers/david_biello David’s work at Scientific American https://www.scientificamerican.com/author/david-biello/ TED talk – ‘Clues to prehistoric times, found in blind cavefish’ https://www.ted.com/talks/prosanta_chak...

Nov 27, 201927 min

Episode 15 – Kristen Johnson & Maria Millan: Regenerative Medicine for Osteoarthritis

Dr. Kristen Johnson is a lead investigator at Calibr, the drug discovery division of Scripps Research. Dr. Maria Millan is the President and CEO of the California Institute for Regenerative Medicine (CIRM). Listen as we talk about the world’s largest stem cell bank, restoring healthy cartilage to patients, and the advantages of non-profit research. Show notes: Kristen’s talk in the Scripps Research Front Row Lecture Series https://www.youtube.com/watch?v=WRzQniqUlHo&t=1941s Coverage of KA34 ...

Jul 21, 201917 min

Ep. 14–Brian Fiske & Jeff Kelly: Accelerating Discoveries to Treat Neurodegenerative Disease

Dr. Brian Fiske is the Senior Vice President for Research Programs at the Michael J. Fox Foundation for Parkinson’s Disease. Professor Jeff Kelly is in the Department of Chemistry at Scripps Research. Listen as we talk about biomarkers for early disease detection, the importance of long-term human trials, and how Parkinson’s disease could originate in the gut. Show notes: Dr. Fiske’s bio at MJFF https://www.michaeljfox.org/foundation/leaders.html?subcatid=381 Prof. Kelly’s bio at Scripps Researc...

May 28, 201919 min

Episode 13 – Eric Topol: High Performance Medicine – How Technology Can Bring Back Humanity

Dr. Eric Topol is the Founder and Director of The Translational Institute at Scripps Research. Listen as we talk about bringing back empathy in medicine, smartphone ultrasounds and the best media for absorbing scientific information. Show notes: Translational Institute at Scripps Research https://www.scripps.edu/science-and-medicine/translational-institute/ Eric’s new book: Deep Medicine https://www.amazon.com/Deep-Medicine-Artificial-Intelligence-Healthcare/dp/1541644638 Current and future appl...

Mar 12, 201922 min

Episode 12 – Arnab Chatterjee: Teaching Old Drugs New Tricks

Dr. Chatterjee is the Vice President of Medicinal Chemistry at Calibr, the biotechnology division of Scripps Research. Listen as we talk about re-purposing existing compounds for new diseases, the future of robotics in drug discovery and our favorite Superheroes. Show notes: About Calibr https://www.scripps.edu/science-and-medicine/calibr/about/index.html ReFRAME Initiative https://www.scripps.edu/news-and-events/press-room/2018/20181003-reframe-calibr.html Footage of Calibr’s robots in action h...

Jan 27, 201923 min

Episode 11 – Matthias Pauthner: Novel Approaches to Combat Infectious Disease

Matthias is based in the Department of Immunology and Microbiology at Scripps Research, working in Prof. Kristian Andersen’s Lab. Listen as we talk about wearable devices to monitor disease progression, research field-trips to West Africa and fancy nights at the symphony. **p.s. if you enjoyed the Christmas jingle, Matthias and I are currently working on an album** Show notes: Andersen Laboratory https://andersen-lab.com/ CViSB Consortium https://cvisb.org/ Burton Laboratory https://www.scripps....

Dec 10, 201829 min

Episode 10 – Alyssa Shepard: Harnessing Social Media in Science

Alyssa is based in the Department of Molecular Medicine at Scripps Research, under the supervision of Prof. Joseph Kissil. Listen as we talk about cancer biology, naked mole-rats and practical tips for improving science communication. Show notes: Kissil Laboratory https://www.scripps.edu/kissil/ Alyssa’s blog https://thecurioussheep.net/blog/ @the_curioussheep on Instagram @_curioussheep on twitter

Nov 16, 201819 min

Episode 9 - Courtney Miller: How To Forget Addictions

Prof. Miller is based in the Department of Molecular Medicine at Scripps Research. Listen as we talk about methamphetamine-use disorder, short- and long-term memory formation, and Breaking Bad. Show notes: Prof. Miller’s Scripps Research bio https://www.scripps.edu/faculty/miller/ Pearson Center for Alcoholism and Addiction http://www.pearsoncenter.org/laboratories-pearson-center/ News coverage of recent work https://eurekalert.org/pub_releases/2018-09/sri-ouc091418.php @millerlab3 on twitter...

Oct 18, 201819 min

Episode 8 – Scripps Research Branding Party Highlights

A compilation of interview highlights recorded live from the branding launch party at Scripps Research. I heard from scientists about how their work is changing life, and spoke with members of communications/marketing/philanthropy about what this new brand means for the institute and the wider community. Show notes: Scripps Research Community Events Calendar https://www.scripps.edu/news-and-events/events-calendar/ How To Connect With Scripps Research https://www.scripps.edu/news-and-events/conne...

Aug 27, 201822 min

Episode 7 – Gary Siuzdak: The Golden Age of Metabolism

Prof. Gary Siuzdak is the Director of the Metabolomics Center at Scripps Research. Listen as we talk about using our own metabolites to impact health status, environmental estrogen-mimics and the potential benefits of Red Bull. Show notes: Metabolomics Center website https://masspec.scripps.edu/landing_page.php?pgcontent=mainPage Gary’s VIVO Scientific Profile https://vivo.scripps.edu/display/SiuzdakGary News coverage of xenoestrogen work https://www.sciencedaily.com/releases/2018/01/18011115510...

Aug 14, 201820 min

Episode 6 – Courtney Peterson: Intermittent Fasting

Dr. Peterson is an Assistant Professor in the Department of Nutrition Sciences at the University of Alabama at Birmingham. Listen as we talk about different fasting strategies, the big bang and the importance of our biological rhythms. Show notes: Dr. Peterson’s UAB Bio https://www.uab.edu/shp/nutrition/about-the-department/faculty-and-staff/primary-faculty/160-courtney-m-petersonProject Time Restricted-Feeding Blog Post http://blog.mycircadianclock.org/early-time-restricted-feeding-for-the-prev...

Jun 25, 201837 min

Episode 5 – Tod Williams and Billie Tsien: The Architecture of a Science Institute

Tod Williams and Billie Tsien are the architects responsible for designing what was formerly the Neurosciences Institute (NSI); the buildings now make up the Hazen Campus and serve as the focal point of The Scripps Research Institute. Listen as we talk about the history of the build, common motifs for all science buildings and the importance of afternoon tea. Show notes: Tod Williams and Billie Tsien bios http://www.twbta.com/studio/people/tod-williams-billie-tsien Project Images of the building...

Mar 09, 201816 min

Episode 4 - Steve Steinhubl: Digital Medicine

Steve is the Director of Digital Medicine at the Scripps Translational Science Institute (STSI). Listen as we talk about Fitbits, perverse healthcare incentives and hiking to Mount Everest Base Camp. Show notes: Steve’s bio at STSI https://www.stsiweb.org/about/faculty/steinhubl-steven/ STSI Precision Medicine Initiative https://www.stsiweb.org/translational-research/precision-medicine-initiative/ DIGIMED 2017 conference program https://www.stsiweb.org/event/digimed17/digimed17-program/ Nature D...

Jan 30, 201823 min

Episode 3 - Matt Tremblay: Technology Transfer - From Bench to Bedside

Matt is the Vice President of Business Development at TSRI, as well as Chief Operating Officer at Calibr. Listen as we talk about what constitutes commercially valuable research, why TSRI is #1 for science innovation and how to design a home jungle gym. Show notes: Matt’s recent Biocom Catalyst Award http://www.scripps.edu/newsandviews/i_20171002/20171002tremblay_biocom.html?utm_source=newsviews&utm_medium=email&utm_campaign=internal20171002 Calibr Bio http://www.calibr.org/about/institu...

Dec 19, 201727 min

Episode 2 - Arthur Olson: Augmented Reality and 3D Printing

Arthur is based in the department of integrative structural and computational biology at TSRI. Listen as we talk about HIV modelling, hexbug toys and human avatars. Show notes: Olson Lab website http://mgl.scripps.edu/ HIVE center http://hive.scripps.edu/ 3D printed demo of viral self-assembly https://www.youtube.com/watch?v=br-YxeXWx6s AR + 3D models to understand molecular interfaces https://www.youtube.com/watch?v=gZxK6j4JTHQ

Nov 06, 201718 min
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