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Sage Toxicologic Pathology & Veterinary Science

SAGE Publications Ltd.www.sagepublications.com
Welcome to the official free Podcast site from SAGE for Veterinary Science. SAGE is a leading international publisher of journals, books, and electronic media for academic, educational, and professional markets with principal offices in Los Angeles, London, New Delhi, and Singapore.
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Episodes

TPX August 2018 Podcast: Preparation of Three-dimensional (3-D) Human Liver (HepaRG) Cultures for Histochemical and Immunohistochemical Staining and Light Microscopic Evaluation

In this podcast, Editorial Board member Elizabeth McInnes invites author Darlene Dixon to discuss her article "Preparation of Three-dimensional (3-D) Human Liver (HepaRG) Cultures for Histochemical and Immunohistochemical Staining and Light Microscopic Evaluation" featured in the August 2018 issue of Toxicologic Pathology. Click here to read the article.

Sep 13, 201816 min

TPX February 2018 Podcast: Evaluation of Uracil, Sodium Ascorbate, and Rosiglitazone as Promoters of Urinary Bladder Transitional Cell Carcinomas in Male Sprague-Dawley Rats

In this podcast, Editorial Board member Elizabeth McInnes invites authors Evan Janovitz and Magnus Söderberg to discuss their article "Evaluation of Uracil, Sodium Ascorbate, and Rosiglitazone as Promoters of Urinary Bladder Transitional Cell Carcinomas in Male Sprague-Dawley Rats" featured in the February 2018 issue of Toxicologic Pathology. Click here to read the article.

Apr 11, 201814 min

TPX December 2017 Podcast: A Diagnostic Approach for Rodent Progressive Cardiomyopathy and Like Lesions in Toxicology Studies up to 28 Days in the Sprague Dawley Rat (Part 1 of 2)

In this podcast, Associate Editor Kevin Keane and author James "Rick" Hailey discuss his article "A Diagnostic Approach for Rodent Progressive Cardiomyopathy and Like Lesions in Toxicology Studies up to 28 Days in the Sprague Dawley Rat (Part 1 of 2)" currently featured in Toxicologic Pathology 's Online First queue. Click here to read the article.

Dec 04, 201714 min

TPX July 2017 Podcast: A Black Cohosh Extract Causes Hematologic and Biochemical Changes Consistent with a Functional Cobalamin Deficiency in Female B6C3F1/N Mice

In this podcast, Associate Editor Denise Bounous and author Michelle C. Cora discuss her article "A Black Cohosh Extract Causes Hematologic and Biochemical Changes Consistent with a Functional Cobalamin Deficiency in Female B6C3F1/N Mice" featured in the July 2017 issue of Toxicologic Pathology . Click here to read the article.

Oct 24, 201711 min

TPX July 2017 Podcast: A Naturally Transmitted Epitheliotropic Polyomavirus Pathogenic in Immunodeficient Rats: Characterization, Transmission, and Preliminary Epidemiologic Studies

In this podcast, Associate Editor Jerrold Ward and author Cynthia Besch-Williford discuss her article "A Naturally Transmitted Epitheliotropic Polyomavirus Pathogenic in Immunodeficient Rats: Characterization, Transmission, and Preliminary Epidemiologic Studies" featured in the July 2017 issue of Toxicologic Pathology . Click here to read the article.

Oct 13, 201717 min

JOVD: Veterinary Dentistry Matters with Sandra Manfra Marretta

John Lewis, former editor-in-chief of the Journal of Veterinary Dentistry , interviews Dr. Sandra Manfra Marretta. The official podcast of the Journal of Veterinary Dentistry , “Veterinary Dentistry Matters,” provides interviews with those who influenced the specialty during its inception and with those who continue to affect its trajectory. In addition to interviews with our specialist colleagues, the podcast will be an opportunity to discuss specific authors’ manuscripts in further detail and ...

Sep 25, 20179 min

JOVD: Veterinary Dentistry Matters with Colin Harvey

John Lewis, former editor-in-chief of the Journal of Veterinary Dentistry , interviews Dr. Colin Harvey. The official podcast of the Journal of Veterinary Dentistry , “Veterinary Dentistry Matters,” provides interviews with those who influenced the specialty during its inception and with those who continue to affect its trajectory. In addition to interviews with our specialist colleagues, the podcast will be an opportunity to discuss specific authors’ manuscripts in further detail and popular to...

May 11, 201726 min

JOVD Inaugural Podcast: Veterinary Dentistry Matters with Mark Smith

John Lewis, editor-in-chief of the Journal of Veterinary Dentistry , presents the inaugural podcast for the journal by interviewing Dr. Mark Smith, the longest tenured editor of the journal. The official podcast of the Journal of Veterinary Dentistry , “Veterinary Dentistry Matters,” provides interviews with those who influenced the specialty during its inception and with those who continue to affect its trajectory. In addition to interviews with our specialist colleagues, the podcast will be an...

Dec 09, 201642 min

TPX October 2016 Podcast: Spontaneous and Dosing Route–related Lung Lesions in Beagle Dogs from Oral Gavage and Inhalation Toxicity Studies

In this podcast, Dr. Sydney Mukaratirwa discusses this study which was conducted to characterize lung microscopic lesions in control beagle dogs from inhalation and oral gavage toxicity studies, to determine differences associated with the route of administration, and to discuss distinguishing features from compound-induced lung lesions.

Oct 26, 201620 min

TPX August 2016 Podcast: Femoral Head Growth Plate Dysplasia and Fracture in Juvenile Rabbits Induced by Off-target Antiangiogenic Treatment

In this Toxicologic Pathology podcast, Stacey L. Fossey interviews author Peter Hall on his article "Femoral Head Growth Plate Dysplasia and Fracture in Juvenile Rabbits Induced by Off-target Antiangiogenic Treatment." Epiphyseal growth plate dysplasia (chondrodysplasia) might be considered as the pathognomonic feature of antiangiogenic treatment in preclinical species as it is reliably and dose-responsively induced in rodents and monkeys with vascular endothelial growth factor receptor (VEGFR) ...

Oct 25, 201616 min

AAFP's Feline Hyperthyroidism Guidelines

The AAFP Guidelines for the Management of Feline Hyperthyroidism (FHT) help primary clinicians answer common questions and suggest when referral may benefit the feline patient. The Guidelines shed light on FHT as a disease and also dispel myths surrounding certain aspects of FHT by replacing them with evidence-based narrative veterinary professionals can directly apply to feline patients and their owners. Listen to Dr. Margie Scherk interview Dr. Hazel Carney about her work on the FHT Guidelines...

Apr 25, 201617 min

TPX October 2015: Scientific and Regulatory Policy Committee Review: Review of the Organisation for Economic Co-operation and Development (OECD) Guidance on the GLP Requirements for Peer Review of Histopathology

This podcast, with Dr. James D Fikes, from Biogen, focuses on the Guidance on the GLP Requirements for Peer Review of Histopathology (guidance # 16) published on September 26, 2014 by the Economic Co-operation and Development (OECD). This guidance represents the first such guidance specifically on the process of Peer Review, which is a widely used tool to assure objectivity and accuracy of histopathology data by submitting it to peer analysis and discussion, before becoming official. This guidel...

Nov 24, 201517 min

TPX October 2015: Immunophenotype of Spontaneous Hematolymphoid Tumors Occurring in Young and Aging Female CD-1 Mice

This podcast with Dr. Jerold Rehg and hosted by Dr. Odete Mendes discusses the classification of mice hematolymphoid tumors in CD1 mice, their pattern of incidence in regards to the age, sex or feeding status and their morphology, cell composition, organ involvement. Immunohistochemical (IHC) markers that are diagnostically relevant for these tumors were also discussed. Dr Rehg characterized the cellular lineage of spontaneous hematolymphoid neoplasms arising in female CD-1 mice. Lymphoblastic l...

Oct 21, 201528 min

TPX: Scientific and Regulatory Policy Committee (SRPC) Review* Interpretation and Use of Cell Proliferation Data in Cancer Risk Assessment

This podcast with Dr. Sam Cohen and hosted by Dr. Peter Hall concerns the publication of a STP committee chaired by Dr. Charles Wood concerning the role of increased cell proliferation in the evaluation of the mode of action of carcinogenesis, particularly for nongenotoxic chemicals. Dr. Cohen emphasizes the importance of attention to details in assessing cell proliferation, with different approaches necessary for various tissues and circumstances. He also emphasizes that the focus is on the num...

Jun 02, 201523 min

TPX: Nonlesions, Misdiagnoses, Missed Diagnoses, and Other Interpretive Challenges in Fish Histopathology Studies: A Guide for Investigators, Authors, Reviewers, and Readers

This podcast with Dr. Jeff Wolf discusses the development of a career in the specialized field of fish pathology, and the use of fish in biomedical and environmental research. As a veterinary pathologist, Dr. Wolf became involved with fish research during his graduate studies and as part of his present job with EPL. Major uses of fish in toxicology include endocrine disruption research, toxicity screening, assessment of environmental contaminant effects, target animal safety studies (e.g., fish ...

Apr 08, 201520 min

A VetPath January 2015 Podcast: Illuminating Dark Cases - Veterinary Forensic Pathology Emerges

Veterinary Pathology podcast editor Leah Schutt discusses the emerging field of veterinary forensic pathology with Sean McDonough, who co-authored the editorial “Illuminating dark cases: veterinary forensic pathology emerges”, which will appear in the January 2015 edition. Dr. McDonough is a veterinary pathologist at Cornell University with a significant commitment to applying the principles of forensic pathology to investigate animal abuse and neglect cases. To view this article, click here ....

Jan 07, 201513 min

5: Feline Dentistry

Feline Dentistry: Jennie Atkinson from SAGE talks to Rachel Perry, guest editor for the two special issues on Feline Dentistry published in the Journal of Feline Medicine and Surgery – vol 16:11 and 17:1 respectively. Rachel is a leading figure in feline dentistry based in the South East of England and Rachel lectures internationally on veterinary dental issues.

Dec 22, 201414 min

A VetPath July 2014 Podcast: Tumor Microenvironment Regulates Metastasis and Metastasis Genes of Mouse MMTV-PymT Mammary Cancer Cells in Vivo

Thomas Rosol discusses the role of tumor microenvironment on cancer metastasis in a murine breast cancer model with Leah Schutt. Dr. Rosol coauthored the paper entitled “Tumor microenvironment regulates metastasis and metastasis genes of mouse MMTV-PymT mammary cancer cells in vivo” in the July 2014 edition of Veterinary Pathology. Dr. Rosol is a Professor and Advisor for the Life Sciences, Technology and Commercialization Office at The Ohio State University. To view the article, click here ....

Nov 14, 201421 min

A VetPath May 2014 Podcast: Systemic Scuticociliatosis (Philasterides dicentrarchi) in Sharks

Leah Schutt discusses an emerging systemic ciliated protozoal disease of aquarium sharks with Mark Stidworthy, who co-authored the paper entitled "Systemic Scuticociliatosis (Philasterides dicentrarchi) in Sharks" in the May 2014 issue of Veterinary Pathology. Dr. Stidworthy is a zoo and wildlife pathologist working in the United Kingdom. To view the article, click here .

Nov 14, 201419 min

TPX: Unexpected Thrombocytopenia and Anemia in Cynomolgus Monkeys Induced by a Therapeutic Human Monoclonal Antibody

A discussion with Drs. Nancy Everds, Nianyu Li and Katherine Sprugel from Amgen in Seattle, Washington about the article “Unexpected thrombocytopenia and anemia in cynomolgus monkeys induced by a therapeutic human monoclonal antibody”. This manuscript won the journal’s best paper award in 2013 and describes a study that is a cautionary tale for those investigating/testing monoclonal antibodies. Click here to read the full article....

Oct 01, 201418 min

TPX: HIV Treatment and Associated Mitochondrial Pathology: Review of 25 Years of In Vitro, Animal, and Human Studies

This podcast provides further insights on mitochondrial pathology resulting from long-term treatment of patients infected with human immunodeficiency virus using cocktails of nucleoside analog reverse transcriptase inhibitors (NRTIs). The respondent is Dr. Brendan Payne, a clinician at the Institute of Genetic Medicine, Newcastle University, Newcastle-upon-Tyne, UK with an interest in diagnosis and treatment of infectious disease--and specifically human immunodeficiency virus (HIV); Dr. Payne is...

Sep 02, 201416 min
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