Lux announced big news today: we are leading a $30 million founding seed round into Sakana AI , a Tokyo, Japan-based AI research laboratory that uses evolutionary methods, collective intelligence and character-level training to radically accelerate the training and development of nature-inspired AI foundation models. It’s a marquee check for Lux into the Asia-Pacific region, and represents the continuing democratization of the frontiers of computer science to all regions of the world, a trend we...
Jan 16, 2024•10 min
Hey, it's Danny Crichton . 2023 was an incredibly busy year, and nowhere was there more fervent attention than on artificial intelligence. OpenAI launched ChatGPT at the very end of 2022, and its implications found purchase this year among more than one hundred million users and the regulators who serve them. Those product developments don't even get into the crazy governance crisis at OpenAI a few weeks ago, which saw Sam Altman and then the board of directors toppled in a story that likely out...
Dec 21, 2023•44 min
In a world where science fiction often paints a pessimistic picture of dystopian futures and critiques of modern technology, novelist Eliot Peper stands out with his latest work, "Foundry." a thrilling exploration of the geopolitical intricacies of semiconductor manufacturing. In this episode of the "Securities" podcast, host Danny Crichton engages with Peper to discuss this engaging spy thriller, which goes beyond the surface to delve into how the tiny chips powering our phones and computers pl...
Dec 15, 2023•41 min
Ever wonder if your dreams were more than just dreams? Dive into an intriguing conversation with Erik Hoel on our latest “Securities” podcast with host Danny Crichton , as we explore the unexpected link between AI, neuroscience, and the enigmatic world of dreams. What if dreams are our brain's way of preventing cognitive overfitting, much like synthetic datasets in machine learning? Could dreams be the human equivalent of synthetic data? This episode doesn't just stop at dreams. We end the conve...
Dec 13, 2023•24 min
In this episode of the "Securities" podcast, host Danny Crichton leads a discussion on consciousness with guests Erik Hoel , Josh Wolfe , and Samuel Arbesman . They dive into " The Consciousness Winter ," comparing it to the AI winter in artificial intelligence. This concept highlights how consciousness studies were once sidelined but have since seen a revival. The conversation covers various theories, including Integrated Information Theory (IIT), and the importance of a mathematical approach t...
Dec 08, 2023•35 min
Welcome to "Securities," a podcast and newsletter about science, technology, finance, and the human condition. In this episode, Danny Crichton and Josh Wolfe discuss themes from Lux Capital 's Quarterly Letter , where techno-optimism collides with the despair of techno-pessimism. The conversation dives into the paradoxes of AI, oscillating between its awe-inspiring potential in transforming healthcare and education and the looming existential threats it poses. Danny and Josh dissect the complexi...
Dec 01, 2023•31 min
In this episode of “ Securities ” by Lux Capital, host Danny Crichton joins guests Brian McCullough , host of the Techmeme Ride Home podcast and General Partner at the Ride Home Fund ; Shahin Farshchi , General Partner at Lux Capital; and Matthew Lynley , founder and writer of the Supervised newsletter to discuss regulation and competition in AI, questioning whether open-source or proprietary AI will dominate the future. With discussions ranging from the impact of large language models to AI’s e...
Nov 17, 2023•35 min
Welcome to this enlightening episode of "Securities” Podcast with host Danny Crichton, where we navigate the intricate crossroads of technology, national security, and democracy. Our guest today is Miles Taylor , the author of " Blowback: A Warning to Save Democracy from the Next Trump ." In this episode, we delve deep into the challenges and complexities of modern governance, the shifting landscape of national security threats, and the role of technology in shaping our society. We explore the i...
Sep 15, 2023•48 min
As the birthplace of semiconductors and computers, Silicon Valley has historically been a major center of the defense industry. That changed with the Vietnam War, when antiwar protesters burned down computing centers at multiple universities to oppose the effort in Southeast Asia, as well as the rise of countercultural entrepreneurs who largely determined the direction of the internet age. Today, there are once again growing ties between tech companies and the Pentagon as the need for more sophi...
Aug 30, 2023•42 min
Artificial life, aka “A-life”, is an intellectually vital field simulating life within computational systems. By allowing simulations to run uninterrupted for extended periods, researchers can observe emergent behaviors, patterns, and even evolutionary trajectories. What's particularly intriguing is that these artificial systems often exhibit behaviors and patterns reminiscent of natural life, reinforcing that certain principles of life and evolution might be universal, whether in a biological c...
Aug 18, 2023•44 min
Think AI can't touch the creative world? Think again. Writers, directors, illustrators - none are safe. AI models, despite their glaring flaws, are on the verge of rendering the vast majority of 'creative' work obsolete. The digital age has already flooded the market with so-called 'creatives', and now AI threatens to wash the least original of them away. We're about to witness the dismantling of creative pathways and the death of apprenticeships. So, where does that leave the next generation of...
Aug 15, 2023•6 min
Historians survey the past and the Twitterati (X-erati?) process the events of the present day. But what does it mean to search the future for clues of what’s to come — and how much longer will we have to wait for it? In this episode of “ Securities ”, Danny Crichton welcomes Lawrence Lundy-Bryan , research partner at Lunar Ventures and the publisher of “State of the Future”, a Deep Tech Tracker whose distinguishing feature is its extraordinarily wide remit to investigate the interstices of scie...
Aug 04, 2023•35 min
Welcome to "Securities," a podcast and newsletter devoted to science, technology, finance, and the human condition. In this episode, Josh Wolfe and Danny Crichton bring science fiction into science fact with our guest, Christopher Mason , a geneticist and computational biologist who has been a principal investigator of 11 NASA missions and projects. Mason, a professor of genomics, physiology and biophysics at Weill Cornell Medicine, discusses his book, "The Next 500 Years: Engineering Life to Re...
Jul 28, 2023•39 min
The rise of generative AI and large-language models (LLMs) have forced computer scientists and philosophers to ask a fundamental question: what is the definition of intelligence and consciousness? Are they the same or different? When we input words into a chatbot, are we seeing the early inklings of a general intelligence or merely the rudiments of a really good statistical parrot? These are modern questions, but also ones that have been addressed by philosophers and novelists for years, as well...
Jul 14, 2023•42 min
The birds and the bees just don’t cut it anymore. With the rising age of first pregnancies in America, optimizing fertility has become the linchpin for potential parents embarking on the journey to childbearing. Even so, we remain beholden to dozens of myths driven by inadequate science, even while we ignore the vast new potential — and limits — of a bountiful set of advanced technologies that aim to make fertility a more understandable and approachable subject. “Securities” host Danny Crichton ...
Jul 07, 2023•31 min
While the natural world is fecund with a dazzling diversity of smells, the landscape of scents in our daily lives is far less organic. A handful of tightly-held fragrance companies and an extremely small guild of perfumers carefully craft the scents that go into every product we purchase, from the scent of clean laundry in our detergents to the orchestrated beauty of scents that make up a modern perfume. Our memories are — without too much exaggeration — controlled by roughly 600 people globally...
Apr 11, 2023•17 min
In a quantified world, the act of creation remains mysterious. Where do ideas come from? How does an artist translate a concept or a feeling into the final work that we get to read or view? The interior drama of that mystery becomes ever more visible as the singular artist expands into a collaboration. How do relationships change the trajectory and originality of creativity? Few novels have better distilled the essence of these questions than Tomorrow, and Tomorrow, and Tomorrow by Gabrielle Zev...
Apr 04, 2023•28 min
We perceive the world through our senses, watching the sunset, hearing the staccato of a violin soloist, smelling and ultimately tasting the chocolate and butter of freshly-baked cookies, and of course, feeling the touch of a loving partner. Yet while scientists have answered fundamental questions about color and audio, from understanding their physics to constructing mathematical representations of them, there remains a huge gap when it comes to smell. Given how much more complex and higher dim...
Mar 29, 2023•27 min
It’s been a long road to mastering the cell, but biological scientists think they are getting closer and closer to understanding the fundamental mechanics of the kernels of life that make up our bodies. Decades after the sequencing of the first human genome, we now have a much more comprehensive understanding of how to discover a cell’s functions — and increasingly, the tools to actually analyze and prove that our models and theories about them are correct. That’s been the domain of single-cell ...
Mar 21, 2023•22 min
ChatGPT has overtaken the cultural zeitgeist faster than any consumer service in the history of technology, with some analysts estimating that it has already been used by more than 100 million people. So when OpenAI, ChatGPT’s creator, live-streamed the launch of its new AI model GPT-4, there was a rush of excitement reminiscent of the Apple product launches of the past. It’s been about 24 hours since GPT-4’s public launch, and all of us here at Lux have already extensively played around with it...
Mar 15, 2023•14 min
The Lux LP quarterly letter has become an institution for its intricate weave of pragmatic cynicism about human nature and unbounded optimism about the power of human progress in the face of macroeconomic forces. We released the latest quarterly letter on the theme of “From Strife to Strive” just before the collapse of Silicon Valley Bank last week. With more strife than ever in the market, where will entrepreneurs strive next? Joining me ( Danny Crichton ) to talk about our analysis of what’s c...
Mar 14, 2023•36 min
While much of the venture world has hit a reset in 2023, you’d never know that in artificial intelligence, where fire marshals are shutting down crammed engineering meetups and startups are once again raising at eye-watering valuations. Why the excitement? Because for founders, technologists and VCs, it feels like the everlasting promise of AI dating back to the 1950s and 1960s is finally on the cusp of being realized with the training and deployment of large language models like GPT-3. To hear ...
Mar 03, 2023•24 min
Artificial intelligence has become ambient in our daily lives, scooting us from place to place with turn-by-turn navigation, assisting us with reminders and alarms, and guiding professionals from lawyers and doctors to reaching the best possible decisions with the data they have on hand. Domain-specific AI has also mastered everything from games like Chess and Go to the complicated science of protein folding. Since the debut of ChatGPT in November by OpenAI however, we have seen a volcanic inter...
Feb 10, 2023•24 min
They say that you miss 100% of the shots you don’t take, but what if each shot costs money and is actually a tradeoff with taking a different shot? Time and money are limited, and that means we must constantly balance investing in our current projects and ideas against seeking out new opportunities. While there has been prodigious work published on how to find the “next big thing”, few researchers have investigated what it takes to just throw in the towel, jump ship, fold and quit in the face of...
Jan 27, 2023•29 min
Technology’s prime and still growing role in society has led to a crescendo of criticism that it has exacerbated inequality. Critics say that the economic models and algorithms underpinning out apps and platforms are tearing apart our social fabric, fracturing the economy, casualizing labor, and increasing hostility between nations. But for all the negativity around technology, there is a parallel positive story of how technology can empower people to achieve their best lives. Whether it’s dynam...
Oct 20, 2022•15 min
No technology has as many dual-use challenges as artificial intelligence. The same AI models that invent vivacious illustrations and visual effects for movies are the exact models that can generate democracy-killing algorithmic propaganda. Code may well be code, but more and more AI leaders are considering how to balance the desire for openness with the need for responsible innovation. One of those leading companies is Hugging Face (a Lux portfolio company), and part of the weight of AI’s safe f...
Oct 12, 2022•23 min
Semiconductors are ubiquitous in modern life, powering our appliances, smartphones, cars and electronics. That’s led to soaring demand from consumers, companies and governments much to the chip industry’s benefit, but its centrality to the global economy has also brought heightened scrutiny from analysts concerned by the deep dependency we have on a handful of companies around the world producing these products. The semiconductor industry is now on the front pages of news sites almost daily, but...
Oct 05, 2022•28 min
We live in a time of tremendous focus on … focus and productivity. Scan the shelves of any self-help section in a bookstore and you’ll find copious volumes on how to focus better, deeper, and longer along with a litany of productivity hacks and habits to efficiently glean. What you will often struggle to find however are books advocating doing nothing. But when it comes to creativity and making deep connections, it’s precisely when we are wandering that we are most focused on invention. To talk ...
Sep 30, 2022•24 min
Episode reading list: The future of crypto regulation: Highlights from the Brookings event Lux + Tactic funding announcement Fourteen years after the release of the Bitcoin white paper , Web3 and crypto are transitioning into adolescence. Technologies and communities that have collectively been a financial Wild West are slowly but inexorably transforming into mainstream infrastructure powering payments, finance, banking, and even identity and data storage. That transition though is hampered by a...
Sep 27, 2022•18 min
Episode reading list: Forging the Industrial Network the Nation Needs Defense Fordism and AI Rebooting the Arsenal of Democracy The Return of Industrial Warfare America spends more money on defense than ever, with a budget that more than doubled in the wake of the September 11th terrorist attacks. Despite those dizzying appropriations though, America is now down to just 5 big prime defense contractors, consolidated from dozens during the Cold War. It’s a pattern of consolidation, higher costs, a...
Sep 21, 2022•24 min
