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Reflections on Parkinson's Disease

A series of Podcasts featuring industry experts: Professor Bas Bloem & Professor Werner Poewe - ‘Reflections on Parkinson’s Disease' podcast, brought to you by Oruen. In this cutting edge series, we will discuss the many miracles, mysteries and myths surrounding Parkinson's Disease. For further information please visit www.oruen.com
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Episodes

Special Edition Episode: Navigating the PD Universe – Live from the BIAL PD Summit 2025 in Lisbon with Guest Speaker Sir Nicholas Mostyn

Join us for an exclusive live-recorded episode of 'Navigating the PD Universe' podcast, kicking off our new series at the BIAL PD Summit in Lisbon, 2025. Professors Werner Poewe and Bas Bloem welcome a remarkable special guest, Sir Nicholas Mostyn, host of the acclaimed Movers and Shakers podcast. Together, they dive into the challenges and realities of Parkinson’s disease, blending expert insights with Sir Nicholas’s personal journey of living with the condition. This candid, inspiring conversa...

Apr 01, 20251 hr 2 min

S2 EP6: ABC of PD - The Letter N: Non Motor Symptoms

Our hosts discuss the Letter N in this episode, focusing predominantly on Non Motor Symptoms. This is a two part episode for the letter N and we are delighted to share this on World Movement Disorders Day 2022.

Nov 28, 202213 minSeason 2Ep. 6

S1 EP7: Apomorphine and non-motor symptoms

In this episode of Reflections On Parkinson's Disease, both professors dive into the history of Apomorphine, the role of the drug within each of their hospitals/for their patients and how the drug impacts non-motor symptoms.

Dec 17, 202115 minSeason 1Ep. 7

S1 EP6: Talking PD - Issues in doctor-patient communication

In episode 6, both Prof’s address the different experiences that they have encountered with their patients during their many years as PD specialists. They discuss ways in which Dr’s communicate with patients on how medication problems may lead to fluctuating responses, what mechanisms can lead to changes in symptom severity and what their take is on the value of aids for communication i.e., wearing off questionnaires, home diaries and other techniques.

Aug 19, 202116 minSeason 1Ep. 6

S1 EP5: The hardships of being off

In this latest Episode of Reflections on Parkinson’s Disease, Prof’s Bloem and Poewe discuss what is meant by ‘on/off’ fluctuations and what it entails. They evaluate the ‘good on and the bad on’ and consider that when a patient is turned ‘on’, medication can sometimes overshoot its target, which means patients develop involuntary movements which are called Dyskinesia’s. The Prof’s then explore the different types of Dyskenisia’s, what problems can arise for patients who are suffering them and a...

Jul 15, 202114 minSeason 1Ep. 5

S1 EP4: Response Fluctuations in Parkinson’s Disease - Why they can be missed

In the anticipation of Euro 2020, both Professor’s share their thoughts on who they will be supporting at this years tournament, before delving into the topic of Response Fluctuations in Parkinson’s Disease and why they can be missed. They discuss how a patients education on the disease is vital to explain what response fluctuations are, the current ways in which patients are recording their experiences and finally whether the use of technology sensors could help patients detect their response f...

Jun 10, 202116 minSeason 1Ep. 4

S1 EP3:Why do patients start to fluctuate?

In Episode 3, Profs. Poewe and Bloem discuss why Parkinsons Disease patients develop fluctuations, how they can be treated & what mechanisms effect this. They also explore the practical elements of combining treatments and whether there are wiser ways of starting treatment.

May 21, 202120 minSeason 1Ep. 3

S1 EP2: Motor Fluctuations and the levodopa long-duration response

In this episode, Bas and Werner delve into the term ‘motor fluctuations’ which is linked to the long-term experience patients have with Levodopa. They discuss a study by George Cotzias regarding the ‘intermittency in the action of the drug’, what the term ‘wearing off’ stands for and the differences between a short-duration/long-duration response.

Apr 29, 202117 minSeason 1Ep. 2

S1 EP1:Levodopa Facts and Myths

In this episode both Professors dispel the myths and misconceptions of a drug that's been used for over 50 years. They discuss the idea of a "honeymoon period" for those using Levodopa and Prof. Bloem also reveals some interesting results from a study he carried out as well as addressing how Levodopa responds to tremors. Special thanks to BIAL for sponsoring this podcast. BIAL is an innovative pharmaceutical company. Dedicated to discovering, developing and commercializing medicines, we are comm...

Apr 07, 202115 minSeason 1Ep. 1
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