Treatment threshold for intra-operative hypotension in clinical practice—a prospective cohort study in older patients in the UK

Intra-operative hypotension frequently complicates anaesthesia and has been extensively associated with myocardial injury, acute kidney injury, stroke and death. The iHypE study aimed to describe the incidence of intra-operative hypotension in older patients and define both the intended blood pressure treatment threshold, and the clinically applied treatment threshold for intra-operative hypotension in UK anaesthetic practice.

The main finding was that intra-operative hypotension is documented in the majority of patients aged ≥ 65 y undergoing surgery in the UK using any of the applied definitions. Prolonged intra-operative hypotension was also prevalent in most patients.

This podcast discusses the how the study was done as well as its key clinical implications. It is essential listening for anyone interested in conducting a trainee network research project and the story of how such a study was coordinated and run is fascinating.