Episode 26: Tranexamic Acid

PHEMCAST

Jan 18, 2018•37 min

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Episode description

https://phemcast.co.uk/wp-content/uploads/2018/01/txa-final.mp3

The paper which we discuss in the interview is available open access here

How does tranexamic acid work?

Taken from: https://pbrainmd.wordpress.com/2015/10/15/1335/

Critical appraisal aids

To understand more about hierachy of evidence and how a systematic review fits into this please have a look at these resources available from the Cochrane group.

http://consumers.cochrane.org/levels-evidence

http://training.cochrane.org/path/grade-approach-evaluating-quality-evidence-pathway

The CASP checklist can be used for assessing the quality of a meta-analysis.

More TXA research trials

Want to know more about the ongoing Crash 3 trial?

Want to know more about the Halt it trial?

References

CRASH-2 (available open access here)
The WOMAN Trial (available Open access here)
The meta-analysis of topical tranexamic acid which Ian mentions is a Cochrane review, available here.

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