Summary: From the DPHARM Archives, this podcast was recorded at the September 2024 DPHARM conference. In this podcast, BMS present how they specifically targeted the challenge of recruiting patients for clinical trials, aiming to make the process faster and easier. By bringing trials directly to patients, their ultimate objective was to significantly expedite patient enrollment. In this case example, they brought the audience through their new product model approach, for the organization's overa...
Aug 22, 2025•16 min
About this podcast: Recorded at the 2025 Immuno-Oncology 360º Summit, Stanford University's Dr Crystal Mackall shares work from her lab developing GD2-targeting CAR T cell therapy for the treatment of deadly pediatric brain tumor, as well as broader lessons on the evolution of cell therapy, and her forward-looking perspective on shaping the next generation of cancer treatments. For more information, go to IO360summit.com .
Aug 14, 2025•29 min
Summary: Rescuing a clinical trial and choosing to switch vendor's mid-trial are some of the most expensive decisions biotech CMOs can make. These rescues require a significant amount of time, money and energy and may not even address the root issue behind a trial's poor performance. In this podcast, Raul Lima, SVP, Strategic Clinical Operations, inSeption Group, discusses a scaffolding approach that prioritizes areas that require immediate support without sacrificing the entirety of the trial. ...
Aug 12, 2025•28 min
Summary: When developing patient-centric products for biologics, different doses, expressed by different combinations of volume/concentration may require different delivery devices. As a result, it takes a great deal of time and effort in planning and coordinating the formulation and device activities. In this podcast, Pharma and Drug Delivery executives from Nanoform, Pfizer, GSK, Takeda and Kymanox discuss how they facilitate partnerships between drug product development, device engineering an...
Aug 12, 2025•28 min
In this podcast series, DPHARM Director Tracey Kimball with Valerie Bowling, Executive Director of the Conference Forum, break down what to expect at DPHARM 2025. Part III of this podcast series covers sessions addressing AI in Clinical Trials.
Jul 25, 2025•6 min
Summary: Accessibility to CAR-T is limited by traditional manufacturing, with its associated challenges and high cost. Moffitt Cancer Center's Chief BioEngineering Officer, Dr Greg Sawyer, highlights Moffitt's significant progress in enhancing T cell potency and boosting efficacy through engineering strategies. Dr Sawyer discusses assays enabling precise asessment of T cell potency, developments in manufacturing, and more, and the resulting impact on scalability and efficiency. This presentation...
Jul 25, 2025•20 min
Summary: In this podcast, Pharma and Drug Delivery executives from Novartis, AstraZeneca, Merck and Quotient Sciences discuss traditional and novel approaches to improve the oral delivery of peptides including: The biopharmaceutics of oral peptide and the use of permeation enhancers Alternate sites for the delivery of oral peptides throughout the GI tract Improving oral exposure through ingestible devices Delivering ASOs and other large synthetics Next-generation approaches for delivery This pre...
Jul 25, 2025•29 min
Summary: In this podcast, Dr Anthony Yanni, SVP, Head of Patient Centricity at Astellas, presented the business rationale for patient-centric medicine development, how it's disrupting the pharmaceutical industry and why companies have to act swiftly to remain competitive. Dr Yanni discusses how to align medicine development with healthcare delivery and the necessary cultural transformation that is critical to sustaining it, practical steps to incorporate patient input early into the R&D proc...
Jul 21, 2025•26 min
This podcast features a panel discussion from the 2025 Chief Medical Officer Summit 360° with biotech CMOs across indications about how CMOs can better develop drugs patients want and derisk development by partnering with patient organizations. Specifically, the panelists address: Patient voice driving drug development forward Supporting health equity and patient access after approval Building genuine relationships and engaging early to get to the right patients at the right time and for better ...
Jul 21, 2025•32 min
Summary: In this session, pharma sponsors and sites gather to present innovative solutions to solve site challenges in workforce and capability gaps, increasing technology burden, patient enrollment and managing clinical trial protocol complexity. They discuss efforts to address those challenges, early impacts and outcomes. In this panel: Dennis Salotti, MS, MBA, Executive Director & Head of Clinical Outsourcing & Innovation, Jazz Pharmaceuticals Kristin Herman, Executive Director, Clini...
Jul 21, 2025•49 min
Conference Forum Director Valerie Bowling and CRAACO Producer Danny McCarthy break down what to expect at the 2025 CRAACO program. This podcast covers the keynotes, panels and key themes for this year's event, including: How to develop a clinical research program within a community cancer center, with Dr Brian Slomovitz, Mount Sinai Medical Center Miami Beach Turning clinical environments into learning health systems, with Dr Laura Esserman, UCSF Carol Franc Buck Breast Cancer Center How to bett...
Jul 08, 2025•11 min
PODD: Partnership Opportunities in Drug Delivery Directors Valerie Bowling and Andrew Goldstein break down what to expect at PODD 2025. This podcast covers keynotes and key themes for this year's event, including: Regeneron Co-Founder and CSO, Dr George Yancopoulos Novo Nordisk Chief Scientific Advisor, Dr Lotte Bjerre Knudsen MIT's Robert Langer Patient Keynote, Jimi Olaghere Northeastern University's Dr Mansoor Amiji Drug Delivery Technology Presentation Tracks Networking Opportunities and mor...
Jun 30, 2025•11 min
This podcast features a panel discussion from the 2025 Chief Medical Officer Summit 360° with biotech CMOs across indications about how CMOs can best support their regulatory teams and engage with the FDA and other regulators. Specifically, the panelists address: Engaging with the FDA on a peer-to-peer level Effectively negotiating about innovative approaches that may be outside of guidelines How to react and respond to feedback and questions from the FDA To learn more about the Chief Medical Of...
Jun 26, 2025•30 min
This podcast features a panel discussion from the 2024 PODD Conference with biopharma leaders about biomaterial approaches to develop implants that can deliver molecules and optimize for dose frequency. Specifically: Defining biocompatible materials and biomaterials Differences between small and larger molecules Benefits and challenges of implants To learn more about the PODD conference, please visit Drug-Delivery.org ....
Jun 26, 2025•29 min
Summary: The consolidation of independent clinical trial sites into larger, integrated networks represents a strategic evolution in clinical research. This panel from the 2024 DPHARM conference discusses whether or not this level of consolidation can bring new researchers and new sites into clinical research, and lead to reduced risk to sponsors, increased predictability, streamlined site operations and greater access for patients. More specifically, this panel focuses on: What is the true value...
Jun 25, 2025•35 min
Summary: Mizuho Securities Analyst, Dr Graig Suvannavejh, joined the 2025 Immuno-Oncology 360º Summit to share an outlook on the IO biotech market, high-level thoughts on the IO space, and public IO company case studies to illustrate the market's perception of what's happening in IO. More specifically: The current tailwinds working for and headwinds working against investment in biotech The increasing specialization of investors and lack of generalist investors The impacts of challenging and/or ...
Jun 25, 2025•20 min
In this podcast series, DPHARM Director Tracey Kimball with Valerie Bowling, Executive Director of the Conference Forum, break down what to expect at DPHARM 2025. Part II of this podcast series covers the 16 Pharma from the Trenches track case studies.
Jun 17, 2025•5 min
In this podcast series, DPHARM Directors Tracey Kimball and Valerie Bowling break down what to expect at DPHARM 2025. Part I of this podcast series covers keynotes and key topics for this year's event, including: Former Merck CEO, Ken Frazier Former Head of FDA, Scott Gottlieb CRISPR Gene Therapy Patient Keynote, Victoria Gray Tuft's Ken Getz How DPHARM is tackling AI What to do about Protocol Complexity and more Want to know more about DPHARM? Check it out at DPHARMconference.com ....
Jun 11, 2025•11 min
About this podcast: Partnerships between industry and patient advocacy groups supply medicine development with critical patient expertise, insights and experience on the journey towards greater patient centricity. This podcast focuses specifically on the role of patient advocacy groups in medicine development in providing a direct, and often untapped, resource for patient insights, community connections and protocol feedback. Dr Matthew Reaney, Scientific Lead, Patient-Centered Solutions at IQVI...
Jun 05, 2025•25 min
This podcast features a panel discussion from the 2024 PODD Conference with pharma, medtech and academic leaders about technological development and patient and clinical adoption of closed-loop systems. Specifically: Success in diabetes and lessons for other indications like oncology and CNS New frontiers in improving closed-loop therapies Increasing access across therapy areas To learn more about the PODD conference, please visit Drug-Delivery.org ....
May 21, 2025•32 min
Patient-reported outcomes (PROs) are increasingly recognized by regulators, clinicians, and patients as valuable tools to collect patient-centered data. This podcast features a panel discussion from the 2025 Chief Medical Officer Summit 360° with biotech CMOs about how to incorporate PROs into clinical trials in ways that improve probabilities of success while avoiding common mistakes. Specifically, the panelists address: How PROs provide evidence on the effect of interventions on patient sympto...
May 21, 2025•33 min
Summary: This podcast from the 2024 DPHARM conference showcases the value of patient engagement as a core strategic investment by focusing on the connection between patient engagement and tangible patient benefits / long-term business sustainability. The case example from Roche uses patient burden and protocol complexity in late-stage clinical development to demonstrate how this connection can be done in larger corporations and to emphasize patient engagement as a long-term growth driver and not...
May 19, 2025•30 min
Summary: In this podcast from the 2024 CRAACO: Clinical Research as a Care Option conference, Dr Meredith Zozus, UT Health San Antonio, walks through several studies illustrating differences in data quality and scalability using EHRs in the conduct of structured protoocls versus retrospective studies using EHR. The results highlight the important methods and approaches for using EHR data in clinicla studies, which is a key component of integrating care and research. For more information, go to C...
May 14, 2025•27 min
Summary: This podcast delves into the critical challenges of scalability in T-cell therapies (including CAR-T, TILs, and TCR-T). The panelists discuss the primary obstacles hindering the increased availability of T-cell therapies to patients, the most promising upcoming approaches to enhance access, the greatest opportunities to improve efficiencies and scalability, and the developments in the near future that could help meet growing demand. For more information, go to IO360summit.com....
May 14, 2025•40 min
Summary: This podcast focuses on the current state of patient centricity within the biopharmaceutical industry, how it's being implemented, operationalized and scaled within organizations, and showing the tangible value of engaging patients. Dr Matthew Reaney, Scientific Lead, Patient-Centered Solutions at IQVIA, speaks with Dr Anthony Yanni, SVP, Head of Patient Centricity at Astellas, to share their experiences, what they've seen in patient centricity gains, standing up patient centricity func...
May 14, 2025•26 min
Summary: In this podcast, recorded at the 2025 Patients as Partners in Clinical Research conference, patient advocate and caregiver Dr Justin Hopkin, University of Rochester, describes his family's journey before, during and after his son was diagnosed with a rare, life-threatening disease. Dr Hopkin talks about the process of getting a diagnosis, the critical role of a clinical trial for his son, the impact on his other children, and his advice for medicine developers and clinical trial designe...
Apr 28, 2025•24 min
Summary: This podcast, recorded at the 2025 Immuno-Oncology 360º (IO360º) Summit, explores the clinical and market implications of emerging data on bispecific antibodies targeting PD-1 and VEGF and their potential to disrupt existing immunotherapy paradigms. More specifically: Assessing the potential of this therapeutic approach to challenge established treatments like pembrolizumab by targeting both PD-1 and VEGF Insights into how these developments could influence industry trends and investor ...
Apr 23, 2025•20 min
This podcast features a panel discussion from the 2024 PODD Conference with pharma and biotech leaders about approaches and challenges in developing sustained release and long acting injectable formulations of therapeutics. Specifically: Contrasting approaches for both biologics and small molecules Next generation technologies to provide less frequent administration Scalable and sustainable ways to provide longer lasting treatments by going beyond conventional sustained release technologies To l...
Apr 22, 2025•31 min
Summary: In this session from DPHARM 2024, pharma experts in data science, digital innovation and development discuss the prerequisites for generative artificial intelligence (GenAI) to work well in large pharma organizations, the change management required to implement GenAI adoption, use cases and lessons learned, ensuring GenAI use is fit-for-purpose, and more. For more information, go to DPHARMconference.com .
Apr 16, 2025•26 min
Summary: New clinical trial execution models have been introduced over the last decade, providing local communities with more direct access to clinical research through remote sites, retail pharmacies, mobile units, site staff embedded in clinical care settings, and more. In this session, recorded at the 2024 CRAACO: Clinical Research as a Care Option conference, Joan Chambers of the Tufts Center for the Study of Drug Development shared preliminary survey results conducted by the Tufts CSDD to h...
Mar 31, 2025•19 min
