Week 16 Picks: Not the same ole Pats, 49ers limping home, and do you trust in Kirk?

With some pivotal rematches on the slate, Florio & Simms pick every game of Week 16.

(3:30) Saturday: Texans at Buccaneers "It would be typical Texans to blow this one."

(6:10) Saturday: Bills at Patriots "This is not the same Patriots we've seen this decade."

(10:25) Saturday: Rams at 49ers "The 49ers understand they can't limp into Week 17."

(17:00) Jaguars at Falcons "I don't think getting rid of Tom Coughlin cures everything in Jacksonville."

(20:10) Why Gardner Minshew could save Doug Marrone's job.

(23:45) Ravens at Browns "The best running game in history is coming to town."

(27:20) Panthers at Colts "I think the Panthers are in not-so-subtle tank mode."

(31:40) Bengals at Dolphins "Joe Mixon's been playing like a superstar the last few weeks."

(34:30) Steelers at Jets "Le'Veon Bell is going to be determined to get revenge on Pittsburgh."

(40:00) Saints at Titans "Janoris Jenkins is a gamechanger."

(44:20) Giants at Redskins "I feel like last week was a sendoff for the season for the Giants."

(50:20) Lions at Broncos "Matt Patricia has gotten his free pass for next year, I don't know how the players feel about that."

(53:10) Raiders at Chargers "I think Rivers delivers in his last home game for the Chargers."

(56:00) Cowboys at Eagles "If the Cowboys lose this game they all deserve to be fired."

(1:01:40) Cardinals at Seahawks "The Seahawks don't put anyone away."

(1:03:45) SNF: Chiefs at Bears "Andy Reid is going to solve Matt Nagy & Chuck Pagano."

(1:08:05) MNF: Packers at Vikings "Do I trust Kirk Cousins? I don't know."

(1:13:25) Chris tries to thread the needle again with one of his Best Bets