Norepinephrine
Jul 04, 2022•1 min
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Episode description
- Trade: Levophed
- Class: Adrenergic agonist, inotropic, vasopressor
- MOA: alpha 1, alpha 2, Beta 1 agonist. Primarily results in peripheral vasoconstriction resulting in increasing BP, and coronary blood flow. Beta adrenergic action produces inotropic stimulation of the heart and dilates coronary arteries.
- Indications: Cardiogenic Shock, septic shock, severe hypotension
- Contraindications: Patients taking MAOIs, use caution in hypovolemia
- Side Effects: Dizziness, anxiety, cardiac arrhythmias, dyspnea, asthma exacerbation
- Dosing
Adult: 2-4mcg/min IV/IO titrate to effect ( systolic BP greater then 80) Max dose is 30mcg/min
Pedi: 0.05 to 2mcg/kg/min IV/IO
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