Labetalol - podcast episode cover

Labetalol

Jul 11, 20221 min
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Episode description

  • Trade: Normodyne
  • Class: Beta blocker 
  • MOA:  Binds with beta1, beta2 and Alpha1 receptors. Inhibits the strength of the hearts contractions, as well as heart rate. This results in decrease in cardiac Oxygen consumption. 
  • Indication: ACS, SVT, severe HTN
  • Contraindications: Hypotension, Cardiogenic shock, acute pulmonary edema, heart failure, severe bradycardia, Sick sinus syndrome, second or third degree heart block, bronchospasm. 
  • Side effects: Usually mild, Hypotensive symptoms, N/V, Bronchospasm, arrhythmia, bradycardia, AV block
  • Dosing: 

Adult 

10mg IV/IO Over 1-2mins may repeat every 10 mins to a max dose of 150mg


Pedi 

0.4-1mg/kg per hour to a max dose of 3mg/kg per hour


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