Dextrose

• Trade – Dextrose (D50, D25, D10)
• Class – Antihypoglycemic 
• MOA – Increases blood glucose concentrations
• Indications – Hypoglycemia 
• Contraindications – Intracranial and instraspinal hemorrhage, delirium tremens. 
• Side effects – Hyperglycemia, warmth, burning from IV infusion. Concentrated solutions may cause pain and thrombosis of peripheral veins. 
• Dosing –

Hyperkalemia:

Adult: 25G of dextrose 50% IV,IO

Pedi: 0.5 – 1G/kg IV/IO

Hypoglycemia: 

Adult: 10-25g dextrose 50% IV

Pedi: Older then 2 years 2ml/kg of Dextrose 50%

Pedi under years old: 2-4 ml/kg of Dextrose 10%