Aspirin

• Trade – ASA(Acetylsalicylic Acid)
• Class – Antiplatelet, nonnarcotic analgesic, antipyretic. 
• MOA – prevents the formation of a chemical known as thromboxane A2, which causes platelets to clump together, or aggregate, and form plugs that cause obstruction or constriction of small coronary arteries. 
• Indication – Fever, inflammation, angina, AMI, and patients complaining of pain, pressure, squeezing, or crushing in the chest that may be cardiac in origin.
• Contraindication – GI bleeding, active ulcer disease, hemorrhagic stroke, bleeding disorders, children with chickenpox or flulike symptoms. Use caution in Reye Syndrome
• Side Effects: None
• Dosing 

Myocardial Infarction

Adult: 160-325mg PO

Pedi: 3-5mg/kg per day 

Pain or fever 

Adult: 325-600mg PO every 4-6 hours

Pedi: 60-90mg/kg per day divided into doses every 4-6 hours