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Oh hey, sold uncle Dad, who's not too proud to shove a finger in each of his ears.
When a fire truck goes by. It's too loud.
Ali ward back with another episode of Ologies.
All right, diseases.
Nobody likes them, not even vectors probably, But isn't it nice to be united in a common dislike of them? So let's clamber down into a big, juicy vat of tickborn illness, shall we? So recovered Acarology a few weeks ago, and I promise that I would hustle to get you a follow up on tick spit souvenirs that they can give you. And this week is the week. Did you come out of acroology liking ticks just a little bit?
Because I didn't. I still hate them very deeply, and they've silently crawled to the very very tippy top my shit list. So let's talk about what they can do to us. But first let me talk about you and just how much I like you. So thanks to everyone who is supporting the show via Patreon. I could not make Ologies without you, And thank you to everyone getting ologies,
merch at ologiesmerch dot com. Also, I put out some social media posts this week that if you got merch in the last few weeks and it seems oddly late, if you didn't hear the secrets at the end of the last few episodes, I had my wallets stolen in a walmart last month. All of my cards were canceled, so there was a delay with the merch site. Anyway, everything is fine out there's still a couple ordershipping out. I'm so sorry if yours was late. I care so
much and I'm so sorry. Thank you also to everyone who is subscribing and rating, most of all reviewing the podcast so that I can lurk and read your nice words and I just pick a fresh fun one each week, such as this one by Maria, who says ology since taught me to look at trees and watch what answer up to I spend so much of my time appreciating the smallest of things, which add up to several hours of my week being filled with both peace and excitement. Anyway,
let's get the hell right into this so disease ecology. Ecology, as we know from the last three episodes, means dwelling that's the root of it or where something lives.
Now. Disease is all French for.
A lack of ease, so simple disease. So a disease ecologist is like, okay, shit, that bums us out.
Where are you? Where are you living now?
This is a great companion episode to the acarology on all about ticks, how ticks work, what they want from us, how stabby are their mouths? How do you get them out of you? So if you'd like to not get a tick born illness, start there for prevention.
That is the base.
That's the one oh one amazing episode with doctor Nita Pardonani Connolly who has a lab in Connecticut.
They know a little aboutics. Okay.
Also two quick corrections before you douse yourself or your life with permetherns, don't use this stuff directly on the skin unless it's been prescribed by doc. Also, check with a vet because liquid permetherne can be toxic to kitties, so ask first about that. Now, if you're like is permethrin the name of a dragon and a fantasy franchise, no again, listen to Acroology. You'll get it.
Okay. So this disease ecologist is one of the best.
She studies the whereabouts and effects of baddies like lime disease and babiosis and other things that like to live in your body without permission. So she's an assistant professor at San Francisco State University. She is a research scientist for the Bay Area Lime Disease Foundation and a member of the California Department of Public Health TICK Working Group. She runs her own lab at SFSU dedicated to research
on these very topics. And she hopped in a sound booth at eight two six Valencia in San Francisco, and we chatted about how many times she's been tick bit, what to do if you find one that's been on you, how animal populations carry lime and other diseases, why possums and western fence lizards are our friends, and what scares her.
The most about ticks.
So button up your cosmic lab coats and take a micro gander at disease ecologist doctor Andrea's way. And so tell me what you study, Tell me what your work entails. This is so exciting.
Yeah.
So my work is really, if I were to summarize it, it's trying to understand diseases and how they're transmitted and how ecological factors, environment and vertebrate can unities sort of natural communities might influence how they're transmitted and where they are. And many of the diseases that I work on happen to be zoonautic, so that means that they're pathogens that are naturally sort of maintained in wildlife and in wild situations and can also cross over to humans and cause
disease in humans. And so zoonotic diseases are a huge part of, you know, the burden of infectious diseases that we see in the world, and many of the diseases that we're facing that are that seem to be new or seem to be emerging actually come from wildlife reservoirs.
A lot of the diseases that we're seeing that are tick born, those have existed in populations, in animals and wildlife well before.
That's right, Yeah, I mean nothing is really new in the sense of you know, spontaneously generating. We're starting to see some of those with antibiotic resistance and sort of new genetic strains, but many of the pathogens that we talk about as being new are they're really just new to us or in terms of causing harm in human populations.
Now, tell me a little bit about when you decided to be a biologist, or when you were like, this is my deal, this is what I'm gonna do.
Yeah, you know, I've been sort of reflecting on that a little bit recently after listening to a few of your shows. And I think it happened pretty early on. I've always really been interested in science. I remember getting my first microscope when I was eleven or so, and I wanted to put everything under the microscope, and I totally got shamed once because someone caught me putting a scab under the microscope. I really wanted to see what
that scab looked like. And you know, then after that, I started doing it more in secret with the things I looked at under the microscope. And it wasn't until I got to college that I took a class and I realized that I really was interested in understanding animal populations and how understanding their populations has all of this relevance or human well being and you know, are sort
of way of life. And so I began to be interested in field ecology, and so I started taking classes that took me into the field all over the place, and I started learning how to do things like trap mammals.
And that was.
Really, I think maybe the moment when I realized that this is really cool. You know, I could go out there and set out a little trap, bait it with oats and peanut butter, and then come back the next morning and they would be like a little surprise present inside, and you know, you didn't know what it was until you opened it up.
Hi, fancy meeting you here.
And so I'd got a lot of experience working with small mammal population genetics, and because I knew how to trap small mammals, I somehow learned about a field assistant position in upstate New York on a lime disease project, and so that's how I got into studying lime disease. So I really got into it for the cute, fuzzy mammals, and then I stayed for the tick boorne diseases.
That's a common marketing ploy, you know, Yeah, stay for the disease. So Andrea got her bachelor's and PhD in integrative biology at UC Berkeley, and her doctoral dissertation was on the ecology of lime disease. But I just had a lingering question. I have a question, did you ever eat any of the oats and peanut butter balls because it sounds really good, you.
Know, I never did, even though it smelled good.
You know, we mix it in these big vats, you know, and it's just not appetizing.
Although, yeah, although you know, my.
Students do make jokes about how, you know, as starving grad students, they can dip into it if they really needed to.
Sounds good, sounds a cookie, though, But I guess in a five gallon home depot bucket mixed with like a stick, it's a little different.
Yeah, exactly.
It's more it's you know, it's really about setting the mood for eating.
And yeah, it's not it. I'm really not very.
And so you were working in upstate New York, And now how long ago was this and how has the prevalence of lime disease or the way we study it change since then?
Well, so this is about twenty years ago that I got this first experience working with lime disease. And I'd say that a lot of what we do, in terms of collecting the data in the field, a lot of that has sort of stayed the same. You know, we go out and we trap these mammals. We look at how many ticks they have on them. We can test
their tissues for infection prevalence. I would say in the lab is where things have changed, where we have much more sensitive techniques, much more specific techniques to detect pathogens. So for a long time, what we do is we would look for the bacteria under dark field microscopy. You could see them swimming around.
So dark field my cross b side note is when the background of the object you're looking at is dark. So the background is dark, it's good for spying on things that you can't stain or that are transparent and don't absorb a lot of light.
So it's kind of like.
Photographing your evening look if you were a limespier keet and no offense, but I would hate you.
And so they're pretty distinctive. You know that you have a spirakeat, but we didn't necessarily know what species of a spire heat we had, and so now we're realizing that there's all of this diversity by using much more specific sequencing methods, and now of course we can look for not only the spire heat, but other microbes and other bacteria viruses that are also coexisting in.
This tick milieu.
So we can kind of look at that whole community within a tick as well.
Okay, so let's direct our gaze and will zoom in online under the scope. And when you talk about lime disease and being a spira keyt, can you kind of explain what that looks like? And if you're like looking at a drop of blood, is it hard to come by the spira keet or is it just allows you with spira keats? Is it just a spira keet party in there.
Yeah? No, that's a really good question.
So it turns out there are a lot of different spire heats and some of them hang out in the blood. These tend to be relapsing fever brilliant and these are things like Brillia mimotoi or early A correesi. These are different types of spirokeuse, the one that causes lime disease and related ones. They actually don't hang out in the blood for very long.
What really, This totally surprised me, and to be honest, ticked me off a little bit.
I said it.
They passed through the blood really briefly. Actually detecting them in blood is not the best way to pick up lime disease infection prevalence, so for that we actually go for tissue. So we'll try to get some ear tissue, or if you have a whole animal, you can go for some other organ. That's where the burlier Bergorpheri, the pathogen that causes lime disease, that's where it will migrate
to eventually and sort of hang out. And the blood it depends on what kind of brillier you're talking about, but if you do see one, what it looks like is just a little squiggle and they kind of vibrate like vibraingly.
You know.
One nice thing about the semester being over is I actually get back into the field and back into the lab, and so earlier this week I was culturing some bacteria and it was so nice to sort of see again under the microscope. I still love using looking under microscopes, and so that was really fun. And when you see the spire keats, they kind of vibrate in the culture and the liquid culture that we grow.
Them in.
When they kind of look I was putting a talk together recently and I made a little pun about a twist of lime, which I was very pleased with and then I realized it kind of does they do almost look like a twist of lime, you know when it kind of curls around, So that's sort of what they look like, and they and they move so they can they use that sort of their whole body to sort of corkscrew through things, and that's how they can tunnel into tissues.
Oh, that's such a brilliant and wonderful visual pun You get like twenty dad joke points for that. That's amazing. Yes, And before we dive more into lime, can you give me kind of just an overview of some tickborn diseases that people might be a little bit worried about. I know, in the tic episode, I've focused a lot on us, but I've heard from Australian friends that there's like a tick paralysis, Like, what are some of the baddies out there?
Well, I mean, certainly lime disease is the most prevalent one that most people will know about. There are actually several different species of Brillia that cause lime disease. They're in the United States and North America. We have Brillia burgdor frye.
In Europe.
There are other species like Brillia fzellii and Brillia garni. They all cause what's called collectively lime burrilliosis.
So there can be different species of Berrillia that are transmitted by ticks and cause lime disease. Now, of the fifty two identified species of Barillia, twenty one are known to cause lime disease or burrelliosis. Now, if you look up a lime spirakeat they're kind of like curly little worm looking bacteria or bits of those little paper streamers that spring forth from a New Year popper. You know, those things are pop those but they're alive and they live in your body. Okay, so a twist of lime
is brilliant. Oh, and that Australian paralysis tick. They tend to be on the eastern coastline of Australia. And it's not a pathogen that does the paralysizing, but a neurotoxin in their saliva. It can cause paralysis and respiratory failure, even death. So what is our motto, check your crevice is now, let's zoom out a little bit and back to some other diseases.
And then in terms of other pathogens, I mean, I think one of the scariest ones to me is poasen virus, which is a virus obviously, but what's really scary about it is it can get transmitted really quickly after a tick attaches, and so within minutes, maybe fifteen minutes or so, it can be transmitted and it's fatal. And so that that sort of cushion of time that we have with detecting a tick for lime disease prevention, we don't actually have that for poalsen virus.
That sucks.
Luckily, it's not very common.
What's the range of that.
It's mostly in the Northeast and a little bit in the Midwest, I believe, but it's pretty limited in distribution.
Okay, So I looked into Poasin disease, named for an unfortunate city in Ontario, Canada, the tourist board of which is probably not stoked because this viral disease not a good one. So some folks won't have any signs, but if you're infected, symptoms could include fever, headache, vomiting, weakness, confusion, a loss of coordination, trouble speaking, memory loss, and encephalitis,
which is swelling of the brain. Just the last month, two folks from Hampton, New Jersey, have come down with poasan virus from a tick bite, and one eighty year old armand des A Moreau.
Did not survive.
So only thirty three people were diagnosed with it in the US last year, so it's very rare, but it can be fatal, so check yourself before it tick recks yourself.
And then other diseases that are emerging are babiziosis, which is caused by a parasite. Actually it's a protozoin parasite that's it's ap complex and so it's related to malaria. So ticks can harbor all these different kinds of pathogens,
really diverse and varied. And babeziosis can be caused by Bibesia microdi in the East Coast, and more recently we've been doing some work on bibiziosis in the West Coast and it turns out that it's caused by a different parasite that's called Bibezia duncan i that has a really different life history, different tick associations, different seasonality.
Okay, Bibizia is not the same as Burrellia, now, I know, I know. They sound like names of twin Ukrainian princesses. But Bizia is around little protozoan parasite. It lives in red blood cells and it gives you symptoms like malaria. Sometimes anti malarial drugs are used in treatment. Now, our other enemy, Burrellia, is that twist of lime spiro keet so Bibisia round lives in the blood cells Burrellia spiral and it goes honky tonkin. It could be anywhere in
your body. It's hard to find. So guess what They both suck And they could both come from a tick. So thanks you tiny thirsty little assholes.
And so one of the things in my work that I'm really interested in exploring is how these ecological changes can lead to differences and how a pathogen is transmitted and what does that mean for you know, disease control and sort of public health awareness, because these different ticks have different affinities for biting different people and then they can, you know, affect different populations. So you need to know what kind of what the vector is. You need to
know where it's found. So there's so many different tick species. One tick species might transmit one pathogen and another one might transmit another one. But a lot of people don't really recognize that there are multiple tick species and that they're a very specific hosts associations, and so you know, sort of getting the word out on that is, you know, one of my research goals.
I'm sure there are people wondering, like who's it more risk? Do they really prefer particular people? Like if you have more sugar in your blood, or you're more caffeinated, or redheads for example, fake redhead, are they at greater.
Risk for instance?
Yeah?
Yeah, I mean there are definitely personal differences between people, so I personally do not I don't seem to be very light by ticks in terms of a blood meal. I've had very few ticks attached to me. And you know, despite working in tick board diseases for over twenty years, I think I've maybe have had two ticks attached to me.
Wow, two only too in that whole time.
And last year we actually tried to I tried to get a tick to bite me for a video segment that this other program was putting on, and it would it refused to bite me. It actually I saw it as it rolled itself off of my arm. So, you know, I think maybe a common theme is that people that work on these things are not necessarily the most prone to getting lots of tick bites, maybe just out of selection or you know, you know, these sorts of occupational hazards.
But so I know that I am not preferred by ticks, and I know that you know, other people, if they come into the field with me for an.
Hour, they will get a tick bite.
So there are definitely those preferences, but I don't know if anyone is really really understands what's driving that, what are the mechanisms behind that. Ticks also have preferences for different host species as well in the field. So we know that like in California we have this amazing tick host that's a western fence lizard.
Those are the blue bellied lizards.
That you often see, bright blue bellies, really ubiquitous in California. Western black leg a tick that we have here, really loves that host.
Oh okay, I hate how cute This next part is thinking of ticks being like whoopy doo, what do I want.
Someone actually did an experiment where they gave them a little bunch of tunnels to different hosts, and one of them had a lizard, one of them had a mouse, and one of them had a bird, and most of the ticks went for the lizard. So they are picking up on pheromones or chemicals or something. But it's really a little bit unclear what that is specifically.
And now that species, if lizard has something in its blood that kind of interacts with the lime spier, keep what is happening there?
Yeah, So that is another reason why that host is so important is that in its blood it has part of the immune system. It has proteins that will actually kill the lime disease bacteria. And so if a tick is infected with lime disease with the pathogen and it bites a lizard, that lizard's blood, the immune system of the lizard will kill the bacteria in the tick and those ticks will all drop off uninfected.
All have She's having wow.
So so yeah, so it's an amazing interaction that we have here in California.
I understand also that possums are big tick eaters. Do they get bitten by ticks a lot or do they just do the biting of the ticks?
Yeah, so I think they What they do is the ticks will bite them and then they'll end up biting them off and eating them, and many of them don't survive.
God, I need more possums and more western fence. I don't want the possums to eat the lizard though, just leave them alone. And so when it comes to lyme disease, can you explain what is happening with it?
What does it do? How does it infect us?
Yeah, so when a tick is out looking for a bled meal. So you know these ticks, the Eastern tick, the western and the western black leg at tick in California, they're sort of related species and they have really similar morphology and sort of general life history traits. But in California we have they have a three year life cycle. So they go from a larval stage, which is the smallest, tiniest stage, to the nymphal stage to the adult.
Stage ps side note, So tick larvae have six legs and then they molt, and the nymphs have eight legs. They eat, they molt, the nymphs have eight so eggs, and then larvae with six legs and nymphs and up have eight legs just in case you're like squint counting at one under a microscope.
And each of those life stages takes a single blood meal. So they will find a host and attached to it, stay on for three to seven days, take a big blood meal, and then drop off until they molt into
the next stage. And so each of those blood meals is an opportunity for that tick to pick up the lime disease bacteria because fortunately there's no vertical transmission of the bacteria, so an adult female that is infected does not transmit that pathogen to her offspring, to her copious you know, thousands of larvae that she lays in these eggs. So fortunately the smallest stage of these ticks, which are
really really tiny. I mean, if you think a poppy seed is small, these are about a tenth the size of that what And they're sometimes transparent, so they're incredibly hard to see.
So side note, those larval ticks have six legs once again, and they're like tiny, tiny little ghosts. And sometimes they're called seed ticks. And I have heard ghoulish reports of walking through a tick bomb containing thousands of these newly hatched nightmares. But they tend not to have diseases because they've not fed yet. But their first meal is where they can pick things up, just like licking doorknobs. So
carry duct tape and pick them off you. Thusly you can just kind of wax a bunch of baby seed ticks off of your body and clothes.
Isn't that disgusting? But it works?
And then throw all your clothes in the dryer on high. When you get home, take a shower, maybe douse yourself in holy wood, take a priest to raging waters and be like Father bless this mess.
Also do a crevice check.
But don't worry too much about the larval ones.
Andrea says, so fortunately they are not infected when they hatch out of their eggs, and so they can only get infected when they take their first blood meal from an infected host. So first I have to find a host, and then if it's uninfected, then they remain uninfected. And if it is infected, then that's when they can pick it up. And so it's that next stage, that nymphle stage, where they can first transmit the pathogen. And so a lot of my work is really looking at where are
these larval ticks taking their blood meal? Is it and sort of what is available to them in their community, and what are their infection prevalences and how good are they at transmitting the pathogen because it's that nymphal stage that's still pretty small that if it bites you, that niphle stage transmits most of the lime disease cases in the United States.
So remember eggs. And then a six legged larval seed tick that drinks annimal blood like a horror villain and gets infected with a disease, molting to become a tiny, tiny poppy seed disease infected eight legged nymph. Then they latch onto your sacred butt crack where it can spread infection before molting into an adult, which can also spread infection.
And so when that tick attaches to you, it has to, you know, prepare itself. It takes a while, about thirty six hours or so before anything really gets injected into you. And at that point is when you start to get the bacteria getting injected into you as it salivates into you.
And then that.
Bacteria, as I said, it only stays in that local area near the tick bite for a very short time. It quickly disseminates through the blood, through the tissues into all over the body. And so that's why lame disease is so hard to diagnose, is it We don't really know where to best look for it. And blood draws, which are the most common ways to detect a lot of other pathogens, don't they work for lime disease.
Just feel free to let out a collective, frustrated grown or scream like a klingon grieving a howl into the sky. I know I did now remember over three hundred thousand new cases of lime a year in the US, and a lot of people might be getting the wrong tests. Also side note, I would like to take this opportunity to just say I had a weird, low grade anxiety attack writing and researching this episode.
Because lime disease is.
Such a controversial topic, some people might not know that I know eight people who have had lime disease, and each of them struggled not only with a bunch of physical issues like joint pains and fatigue and headache and autoimmune issues and brain fog, but also had to deal with this weird emotional maze of some people or some doctors not believing that they were still struggling with lime
symptoms after treatment. So this is known as the lime wars. Now, in terms of chronic lime disease, the CDC does not recognize chronic lime disease as a thing now. Symptoms could linger for years, and some doctors do acknowledge post treatment lime disorder. Now, around ten percent of patients who get lime disease and are treated for a few weeks with antibiotics won't fully recover, so these patients might ask for longer courses of antibiotics or have to follow certain anti
inflammatory dietary protocol. They might try supplements or other ways to try to fight this biakeet, which some research suggests can hide in a little cloak called a biofilm, so it's hard to kill. So chronic lime disease poo pooed by many. Some doctors acknowledge post treatment lime disorder, but there's still a lot of flim flam out there. There's a lot of skepticism. There's also a lot of people who are just still suffering from symptoms of lime disease,
and people don't know why. I read a blog post from a doctor at Harvard who said it reminds him of the first stages of HIV and AIDS, when there are a lot of rumors and not a lot of research, and a lot of patients were getting blown off by doctors, so more research. In hindsight, we'll probably look back and think, Wow, what a big, murky mess. But the first step to any of this is getting a diagnosis, which Andreas said that blood draws don't really work that well for lime disease detection.
What does work?
I mean, I know, it seems like so many people are frustrated by maybe feeling like they have lime disease, but their tests show they're fine. So what is medical science doing to address that?
So, you know, erology is one way that you can detect things without detecting the thing, right, you're detecting the signal sort of the immune response to the pathogen that you're interested in. The problem with zerology is not very specific, and so you often get cross reactivity, so you'll get things that will have the same signal, and so it's really hard to say for sure whether or not this zerological signal matches the pathogen that you want to definitively diagnose.
Oh hey, seriologists holler at your dad.
And so that's why it takes so many markers of these zerological approaches to be able to say this is definitely a lime disease case. And so this is what led to the CDC two tiered you know, testing to make sure that you are not picking up false positives. Now there are approaches now that people are trying to develop to be more specific and more sensitive, you know. So one possibility is maybe looking at the host immune response.
Now we can look at gene expression in different individuals, and it's becoming cheaper and cheaper to do that, and so one way might be to look at what genes are upregulated in an individual who has had acute infection with lime disease or maybe a longer term infection with lime disease. And so there are other methods and maybe other secreted proteins that might also be picked up by some more sensitive tests, and so there are people that are working on better diagnosis. But it is a really
difficult problem. It's something that it just really has to do with the way that the bacteria behaves in our bodies. It doesn't stay in one place for us to pick up really easily.
Okay, So side note.
I looked up what these gene expression tests are all about, and a twenty sixteen study published by s F University and Johns Hopkins University show that in people infected with Burrellia, remember, causes lime. There's a unique gene expression pattern in their white blood cells, so certain genes turn on or off when infected with lime, and that continues even after their antibiotic treatment. So more of that gene expression testing might be on the horizon, or or you could just ask
a witch to turn you into a rat today. Why can't they use the same type of tissue tests that you would use on say a mouse in the field, on just a human being could use the same kind of thing, like I'll side your piece of my ear.
Actually, I don't know.
I mean we probably we know that when we take a little bit of the mouse ear that we are not necessarily catching every single case, right, it's kind of a sample, and so our objective isn't necessarily to diagnose every single mouse. We're trying to get kind of a population level average, and so the objectives are a little bit different. But I do think that probably tissue biopsies
would be more effective than blood draws. But it's really hard to convince people to undergo a tissue biopsy, right, It just I don't think it's practical, and so it hasn't really been discussed as a potential way forward. But certainly you know if at the site of the tick bite, if you get it early enough, a tissue biopsy would you would get the bacteria there.
They should just offer free ear piercings with every test. That way, at least you walk away with a new piercing tiny bit of tissue.
I'm sure that it work fine. Okay.
Side note, I just looked up how much gauging your ears cost and it can be like seventy five bucks a pop. But lime disease tests could be in the hundreds, depending on your insurance. Now, they usually start with an enzyme linked immunoabsorbent assay or an ELISA test. Those look for antibodies, and then something called a Western blot test can confirm, but according to some research, those are only
about fifty percent accurate. Now, some folks who have been diagnosed with limes say that the immunoblot igen X tests are more effective at detecting it. But ask your own doctors if this is something you suspect that you have. Again, this is just a podcast. I'm not your doctor.
I'm sorry. Now.
In researching this, I stumbled across just such a dark go fund me blog post from the company just subtly suggesting the best ways to crowdfund for lime treatment since most insurance companies don't cover much beyond that first round of antibiotics for an initial diagnosis. So good to know that help is out there in the form of suggestions on how to crowdfund your medical treatment here in America. And so, what exactly is lime doing in the body?
Is it causing a lot of inflammation? Is it affecting neurological function, joints? Where is it hanging out?
Yeah, I mean pretty much all those things you just mentioned. I mean it will go. It'll sort of embed itself into joints, into muscular tissue, neurological tissue, and cause inflammation and a lot of what we think some of the maybe longer term symptoms might be. Or it might just actually be the immune response responding to that infection of trying to fight it. So sort of, you know, a regulated cytokine inflammation that leads to a lot of the swelling and pain that people associate as well.
So the bodies of immune system kind of freaks out, and chemical messengers name cytokines might kind of still be ringing the old fire alarm, which triggers inflammation, which can cause arthritis like symptoms. Now, some folks with post treatment lime seem to feel better on anti inflammatory diets. You know, we skip ingredients like gluten or sugar. So if someone doesn't have technically celiac disease, which in itself is a serious and huge bummer, but someone's eating gluten free or
sugar free anyway, Just give people a break. People know their own bodies best. Let them eat or not eat what they don't want to eat or not eat anyway. Autoimmune disease and inflammation to be discussed in a future rheumatology and or immunology episode, is that, how maybe it could be linked to autoimmune disease because your body's immune system just freaks out.
There are some similarities to how some people respond to a lime infection and some autoimmune diseases. It does seem like it may have some sort of long lasting immune consequences that, you know, maybe even after the pathogen is gone, it might still be that the immune system is sort of sort of oversensitized.
Do you ever have to get involved with the debate between late stage lime and chronic limes? Do you kind of stay apart from that medical kind of controversy or do you have to weigh in it all well.
I actually did a short post doc where I studied that issue where we were really trying to look for some of these gene expression markers in people with this late late stage lime disease. We didn't really find a really clear signal there. So I have worked a little bit on it, and it's really complicated there. I know there are good people that are trying to come up with better diagnostic tools, and people that are trying to work on vaccines and on all these different things. The
bulk of my work is really on the ecology. And so you know, one thing I always say is that if you have a tick, if you pull the tick off of you, we can test that tick and be fairly certain whether or not it's infected or not, because it's much easier to do that than to try to query an entire human body right and not really knowing whether or not we're picking up the pathage or not. But if you give us a tick, we'll crush the whole darn thing up exactly.
See I'm crushing.
It, and we can look for the pathogen in the tick. So we can't really do that with humans, so you know, we can do that with a tick.
And so a lot.
Of my work is really really focused on the tick ause we can learn so much from it. Our diagnostic tests and tools are much more effective when you have a tick.
If people say, pick a tick off and they put it in a freezer bag, you know, like a little ziploc. Are there labs that would be like send me your ticks or is that pretty hard to come by?
There are actually increasing the numbers of labs that will do that. You can send them your ticks. I know Area Line Foundation does that Tick Encounter might also do that. I just heard about another organization that'll take your pets ticks as well, and they don't necessarily test them all and they and you may not necessarily get a test
result as a result right away. But I know there are these a lot of agencies that are trying to use this method to surveil tickboarn pathogens much more broadly and comprehensively by having people send in their ticks.
Side note, Okay, I look this up and the tick encounter dot org site. Remember that was the nonprofit that acarologists Doctor Nita Pardonani Connolly chose they have great resources. That's tick encounter dot org. And they pointed to tick report dot com which has instructions on how to send in a tick for testing, and it costs fifty bucks per tick. But it includes Burrellia which is the spirokeet, the lime causing one, and Pibisia which is that round
malaria like protozoin. Also in that same test, it includes powassin and Rocky Mountain spotted fever, a whole host of things and results can come back in seventy two hours. So that's tickreport dot com. So they have info on how to send in your non alive ticks that you have plucked off of your or a loved one's body, good ticks that is. They also send a micrograph of it in case you just want to look at it up close. Maybe print out a picture and have it framed,
make a dartboard. Now, what about distribution of tick born diseases. As a disease ecologist, Andrea fundamentally studies where these bad feeling causing things dwell. And now one thing that I found so fascinating looking at your research is the percentage of ticks that are infected with lime, even on the West Coast. It seems like a big myth is that lime is only in the northeast, and chances are there's no way you could get it in California.
But you do.
You do a lot of field work, like in Tilden and in the areas around San Francisco.
Yeah, I do, so most of my field sites are from northern California.
Actually, the hotbed.
Of lime disease on the West Coast is from about I would say, the around San Francisco up north into Mendoesino County along the coast. They need, we need certain conditions, so they need it to be moist, they need certain habitat, they need to have all of these different hosts required to complete their life cycle. And so there's really kind of a narrow range where they can be found. But in California, that range is sort of the entire coastal
region of California north of i'd say Santa Cruzer. So after that flower down south, it becomes much too dry for them, although you do still see them, and I do have some projects down south, so I don't want to say that it's not there, but the majority of tick abundance, how the highest tick densities are along those northern areas, and also infection prevalence can reach you know, twenty to twenty five percent in certain areas, so pretty high prevalences.
Twenty five percent.
There's so much groaning in this episode, but I feel like it's warranted.
Yeah, But I think one of the things that distinguishes how the West Coast is different from the East Coast isn't just the ecology. It's also the way that humans interact with their environment. And so I think on the East Coast, a lot of people live in the woods. You know, they have these houses that are surrounded by secondary forests that has been known to come back with lots of the hosts that are responsible for maintaining tick populations. In California, we have a lot more sort of primary
growth forests that hasn't been cut down before. We have a lot of logged areas too as well.
But the way people.
Come into contact with with ticks, it tends to not be around the home as much. You know, most people live in more dense urban areas and so to encounter a tick, it kind of means you're camping or you're biking, or you're going on a hike or something and so, and a lot of the work that I'm doing is looking at how habitat fragmentation size influences things like tick abundance and also the community composition of the vertebrate hosts
that are involved in tick ecology. And so some of the bigger sites are where we have more diverse roadent communities and where we also have top predators, so we actually have a lot of intact, relatively intact food webs, and the West Coast where we have sites with puma still wandering around, and so those help to control the deer populations, and this is something that they don't have
on the East Coast. So I think a lot of these ecological differences also are shape being the differences that we see in lime disease ecology in California.
I was going to put a really bitchy West Coast best coast clip here, but honestly, all coasts and areas inland are lovely. We really don't need to heighten these lime wars with any regional rivalries. We may have ticks crawling around our crotches giving us diseases, we don't need any more drama today. I love you all. Please check
your bodily crevices. Yeah, you know, I've seen some people argue that doing more deer hunting would actually help control the deer population, and it's kind of better ecologically than maybe eating factory farmed meat as a disease. Ecologists, do you see too high a deer population is a kind of a consistent problem or is that a myth?
No?
I mean, certainly on the East Coast, the deer populations are really unchecked, right. There isn't that much hunting and there are no top predators that are keeping those populations down, so deer are important part of that equation. I think here in California the deer populations are a little bit more stable.
They have predation.
I don't know if hunting is more or less common here, but I certainly think that, especially in areas where you don't have natural predators, of deer hunting might actually help stabilize those populations.
Right, And I know different wildlife ecologists advocate for that. I'm sure some others are disagree with it, but it does seem if we've killed off a lot of the wolves and the pumas in some areas that everything could kind of get.
Out of whack a little bit. M okay.
Quick side note, I just read an article that addressed Connecticut deer populations and although they are reaching lower, hill healthier levels due to some yearly hunts, one guy, Stefano Zandri, who's a chairman of a deer management implementation committee, says that winter flyover counts like a census of deer averaged forty two deer per square mile in some parts of Connecticut, and some ecologists want to see it closer to twenty.
So I also started getting lost looking at statistics and figures of roadkill incidents with deer before these town hunts were started, and about an equal number of deer died from being hit by cars as do now from hunting. But now the roadkilled deaths have plummeted, so about as many deer die with fewer accidents and more deer used for food. So I'm very much not a person who loves to think about animals being slaughtered, but ecologically I
see the pro Connecticut deer hunting point. I'm so sorry, dear. What about speaking of meat, what about this lone star tick meat allergy situation?
What is oh?
Yeah, yeah, No, that is a really interesting thing. So that isn't a pathogen. That is just the saliva of the tick, and so the tick doesn't have like another it's not transmitting any kind of pathogen. It's just proteins in the tick saliva that are inducing this allergy. An analergy to alpha gal, which is a protein that is found in mammals. So you know, basically it's called a red meat allergy, but it's really a mammal allergy.
Wow, did that start recently or are we just hearing about it more?
You know, it does seem to be much more common, and I don't know why. I don't know if it's because the ticks aren't becoming more abundant or common, but they are a very aggressive tick and they do seem their populations do seem to be growing.
But I don't know.
I don't work on that species of ticks, so I don't know if there's good data to support that or not. But certainly the reports of these red meat allergies are becoming more common.
By the bye.
I was like, lone star ticks. Yeah, they got a big white dot on the back. I got it, but I just looked it up and only the adult females do. So tickincounter dot Org has you covered on what every stage looks like, and it also says that lone star ticks are very aggressive biers.
I hate them.
Also, ticks, I just fucking do not like you. I tried to wonder at you and respect you. But if I had a genie with a lamp, I would be like number one global warming fix cancer figured out number three ticks fuck off and die. Anyway, this alpha GL acquired meat allergy with lone star ticks can cause serious reactions from the meat of mammals, from their dairy products, even from gelatin from their hooves or exposure to wool fibers.
So it's a huge pain of the ass. About five thousand people a year in the US get this alpha GL sensitivity, which is up from thirty five hundred two years ago. Rising temperatures could be a play also in a sense just increased awareness. Yeah, I wonder if it's just because we have more Twitter, so there's more like my cousin got that, you know, or like there's just
we hear about it more. Are there any myths about tickboarn diseases that really as my dad would say, fryer legs, which means make you mad.
Yeah, I mean I think, Well, the biggest one for me is that a lot of people think that there is no lime disease in California, and you know, as someone who has been studying it for a while, that's definitely here. You know, when my field assistant our students have it an exposure to a tick bite and they go in to see a doctor, a lot of times they just won't consider lime disease, and you know, and we have to tell them, look, we have the ticks
in this habitat. We know that the infection prevalence is twenty percent, so you know, give me the pro antibiotic. So we do have to push for that sometimes knowing that we are in these risky habitats. But a lot of people really don't know about it. You know, it's definitely not as common or as prevalent as it is on the East Coast.
There are about a.
Little over one hundred cases a year in California that are not travel associated, so you know, figuring out which ones are sort of locally acquired, but it is definitely here, and you know, probably is in certain areas more common than we think so like having.
To watch live shows that are actually pre taped and aired three hours later. The West Coast gets East Coast feeds, just on a little delay this time. I guess it's to our benefit. Now, my friends who have been diagnosed with lime have mentioned co infections, so I wanted to ask what was to deal with that?
So I did.
Do you find that there are a lot of co infections in ticks? I've heard about that a bit, but where maybe someone might not just have line, but they'll have a few different things happening at once.
Yeah, I mean that can certainly happen. I think it's more common on the East Coast, where burli at Bergdorfia, the lime disease pathogen, and Babizia microdi tend to be co transmitted more often than you would expect by a random chance. So there are some risk of co infection there. But in California we don't see a lot of co infection.
You know, a lot of the pathogens that we look at are pretty rare on their own, and so the chances of seeing them in the same tick vector or in the same host is pretty rare.
Okay, So co infections This is like the two Ukrainian princesses, Burrellia and Bibizia, just hanging out together in your blood. But it's more common on the East coast. Also, I don't know anything about Ukrainian royalty, so I just had to google.
Does the Ukraine have princesses?
And I've found some history on one name, Olga, which does not sound like a tick born disease. And then I started looking up gendered Ukrainian baby names to see if any even sounded remotely like Burrelia or Bibisia. Literally, none of the popular Ukrainian baby names even started with a bee. They were like Anastasia, Yelizaveta, Aleksandra.
And I was like, does Ukrainian even have a B?
Yes, the Ukrainian alphabet does have a B, but shit, it's pronounced like a V. So I'm sorry Ukrainians who have been screaming at me while you're driving in your commute. But Bizia and Burrellia would never be Ukrainian princesses. But at least you know now there are different diseases from tics, and one is a lime spirokeet burrellia and the other is a round parasite that lives in red blood cells. But bizia right, Let's just change the subject.
Okay.
Can I ask you some Patreon questions listeners? Okay, so listeners have a bunch of questions. Okay, So now is
the time for your questions submitted through Patreon. And before we get to those, we have some words from sponsors of the show, who make it possible to make a donation to a charity of the ologists choosing, and this episode we donated too, one being eight two six in San Francisco, who hosted Andrea for the recording of this episode, and which is a nonprofit organization dedicated to supporting under resource students ages six to eighteen with creative and expository
writing skills. It's a really awesome literacy program. I love them. They also have a storefront at eight two six Valencia in the Mission District of San Francisco, where you can purchase Pirate supplies highly recommended. I have several fake mustaches from that establishment. Now, another donation went to the Union of Concerned Scientists. Andrea chose them and said they are a wonderful science advocacy organization of nearly two hundred and
fifty scientists, analysts, policy and communication experts. They're dedicated to combating climate change, developing sustainable ways to feed and power and transport ourselves, to reduce the existential threat of nuclear war, to fight back when powerful corporations or special interests mis lead the public on science, and to ensure solutions to the issues advanced racial and economic equality. So two great
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Okay, back to your questions.
Ruby Asterich asks how close are we to a human vaccine? The dog one is very effective and lifelong ramifications of lime disease are awful. So can you tell me a little bit about how the vaccine works and how it works on pets versus humans.
So this isn't my area of specialty, but from what I understand about the vaccine is that, you know, there was a human vaccine that was available and was pretty efficacious, and it was taken off the market for a couple of reasons. One was that the sales were not that good, and the other one was that there was a class action lawsuit against the manufacturer. But I think subsequent to that they found that there really was no biological reason
why it should have been taken off the market. And so basically what it is is that the you know, it was FDA approved already, and so there are vaccines in development that are basically the same as the previous vaccine, but I think, as far as I don't know of any company that has sort of taken that on because of the difficulties that they had previously.
So the Centers for Disease Control website states grimly quote, a lime disease vaccine is no longer available. The vaccine manufacturer discontinued production in two thousand and two, citing insufficient consumer demand.
End quote.
I feel tonally, this is like when someone wants to shit talk someone else so bad but remains diplomatic, like the split is amicable and we request privacy during this time. You can vaccinate your dog, though, and according to one study published by the Companion Animal Parasites Council, nearly six percent of five million dogs tested in the US did test positive for lime infection. But the lime vaccine doesn't
protect against other tickborn infections. So one vet doctor, Betsy Brevitts, called the lime vaccine like wearing suspenders when you're already wearing a belt. It's a good backup, but the belt is really tick control, and that's what's most important. So do tick checks whenever your pup comes in from outside potty, going out on a wall, or just going romping, and ask your vent about good tick killing agents because that's number one.
Same for kiddies.
Okay, But back to that whom in vaccine, is there any hope for us?
And so there there, it's very likely that a vaccine will be developed and then your future because we had a good working vaccine before, there's no reason, no biological reason.
Why we don't have one. Now, I think a lot of it is more financial and political.
Yeah, oh that's a bummer. I'm like, get that recipe down, let's remake that. I would have that in a second. Savashari says, I live in Germany where tick born encephalitis has had an outbreak and there's apparently no cure, and their husband, a doctor, says that the tick has to be on you for two days before you can get any diseases from it.
Heard anything about it.
I don't know as much about the transmission of tickborn and cephalitis, but if it's anything like lime disease, it does take a couple of days for pathogens to well, at least the you know, bacteria pathogens to be transmitted, because the tick just takes a while to have the pathogen move from the midgut to the salivary glens and
sort of settle in for that blood meal. But I'm not exactly sure how long it takes for tickborn and cephalitis, which I know is a big problem in Europe, and it's transmitted by the same tick that transmits lime disease.
There.
Oh really, okay, that's interesting.
So tick born encephalitis or TB, by the way, can be what's called bi phasic. So it first presents with either no symptoms or about a week of vague symptoms like fever and fatigue, maybe muscle ags, headache, kind of barfiness like a flu, and then things calm down, you feel better for a week, You're like, look at me, let's sprung back. And then the second phase hits and that's neurological and it can involve meningitis, brain swelling, paralysis,
with a death rate of up to two percent. There is a vaccine now, so folks in riskier areas for TBE, like central Eastern Europe, northern Asia. At least you're as protected as our dogs are from lime in America. So that's a plus. Oh, back to lime and pets. There were more questions about this from Brin Spear, Hannahalise Tricia, Emmy B. Marky, Seymour, Sarah Patterson, Any Burwell, and Isabeut
b Holper. A few different people kind of wanted to know if the symptoms and pets are similar to what humans get.
I'm not exactly sure.
I do know that dogs can get arthritis and joint pain and so, but I would imagine that a bulls eye rash might be a little bit more difficult to detect in a pet, but I would imagine that a lot of the symptoms, the acute symptoms would be pretty similar.
Okay, now what about that rash? I have a hard time pronouncing. First time question asker Donnie Wald asks why does the rash look like a bullseye? Why do some infected people not develop the bulls eye rash?
ARETHEMA migrants?
Yeah?
I new I would say that wrong. Why exactly does that happen? And does that happen on? Like if a raccoon gets lime diseased under its fur, does it have a target logo bulls irash.
It has to do with the immune response.
So basically, there's an local inflammation that happens and it sort of spreads out. I'm not quite sure why the white ring forms, but it has to do with that that local as like the immune system is recruited to that local site.
Is what causes that distinctive rap.
Kristin Long wants to note this feels like a stupid question, She says, but is it possible to get lime disease without a tick bite or all cases related to tick exposure. Like I've heard that maybe mosquitoes can transmit it, but I didn't know if that was flim flam.
I haven't heard of any other methods of transmission. It's possible that, you know, if you're working with it in the lab, if you have a culture of it. It's plausible that if you get a culture, a live culture on your unprotected skin, that you could get infected that way, because it does start out as a dermatological infection. And so that's why when we work with it in the lab, we work under biosafety level two conditions just to make sure there's no to minimize the risk of transmission in
that particular setting. But I think a lot of the other methods of transmission are not really really proven ps.
I was curious what kind of precautions a biosafety level two lab had to take, because I instantly envisioned just like a bunch of scientists in biohazard suits just talking about their weekend in the breakroom. But really it just involves lab coats and gloves, face shields as needed, an eyewash station in the lab, self closing lockable doors, and some biohazard warning signs. All of which are also just
a great way to keep people out of your cubicle. Probably, but yes, getting back to it, other methods of transmissions like mosquitoes, she says, are not really proven. Also the question all of us want to ask but feel like people Beatrice Rumford wants to know. Is it okay to kill ticks because they are disease vectors? Or do they play an important ecological role and I should just let them live their lives.
I say that you should probably kill anything that you come across. That's totally fine. I mean the ecological role.
I'm sure there are animals that eat them. They probably play a role.
They might actually play an important role in sort of population regulation, in terms of keeping certain populations that are really abundant. If they have high tick burdens, it might actually slow down. So there might play an ecological role, but I would say it's a minimal one. If you find a tick and kill it.
Okay, is it best? What's the best way to kill it? Just smush it with a rock?
Huh?
Well, I mean the way we do it is we put them in ethanol.
I think if you were at home, you could probably put it in scotch or something.
That you have lying around, maybe not your best Scotch put it in like, yeah, not the age some Gilby's gin from a plastic bottle.
Let's see.
Crystal Mendoza has some questions, says, what is up with Himiphysalis longe purnis And how scared should we be fully freaking out about it?
Is that bad?
And she says sorry for the multiple questions, but I work in a tickborn virus lab, so she also does tickborn work, So how scared.
Should we be with hey, mafia salas as long as.
So humo phi Sylus longic cornas humor Phisylus longic.
Cornas aka the longhorn tick.
This is a invasive tick that was just picked up recently on the East coast. It's sort of spreading. I have to say, it's a little it's a little concerning, you know, it's spreading pretty rapidly. Control pretty much. I know a lot of people that are working on the species, and it's really hard to control tick populations, you know. It's it's really difficult to do that because they just are not like even like mosquitoes, where you can go after the water body breeding sites or anything like that.
They're just all over the environment. And this particular species can actually undergo parthenogenesis, so it can clone itself and so it doesn't even need a male tick to you know, complete its life cycle. So I don't know if that means that it can reproduce faster or not, but it probably does because I think one of the limiting factors for other ticks is that they have to meet each other on a host like a deer. That's that's sort
of the tick hookup spot. I know, the males will hang out there and wait for the females with me, please. The males aren't there for the blood meal, because they don't take a blood meal. They just are there for the females and then they'll breed on the host. So for this invasive tick species, they don't need that, and so potentially their their populations could be could sort of
expand at a much higher rate. So I'm a little concerned, and I'm not someone that sort of goes to that emotion very quickly, and so it's a little bit scary that it's here now and it's spreading and we don't know how to control it.
Yikes.
And what's the scariest disease it might have.
I know it has carries a disease in Asia, where it's from, but I don't think that pathogen has been picked up here yet. Cool, but I can't remember the name.
Okay, So this longhorn tick can spread. According to my friend Wikipardia lime spira, keets spotted fever, Aerolictia chaffansti, Russian spring summer encephalitis, powasin virus, cass and virus, tickborn encephalitis virus, Japanese spotted fever. But the one I think she was referencing was the not at all catchy sounding SFTS or severe fever with thrombocytopenia syndrome, which in northeast and central China has a fatality rate of up to thirty percent
thirty percent. Now, so far, none of the long hornticks found in the US have tested positive for these diseases, but the fact that they just showed up and are spreading is freaking people all the way out, to put it scientifically, so welcome to my shit list, longhorned tick.
You deserve to be here.
Christina Meers says, I live in a rural area and although folks have kept poultry for various reasons forever more and where I hear about how great they are at controlling tick population. So I'm wondering if any one domestic bird species is better than the rest, like ducks, chickens, guineas, or should we just work on domesticating possums instead, which is an idea that I love.
I would think that chickens would be pretty good. I think a lot of the tick populations will not be particularly high in a backyard setting, you know, because they do need all of those different host species to complete their life cycle, so they're not going to be able to They shouldn't be very abundant in your backyard anyway, But couldn't hurt to have some chickens. I think they would. They would probably do an okay job. But yeah, heard
of that as a control measure. But maybe you could create a little perimeter.
The chickens, just a chicken patch.
Dan Starrett wants to know is it true that ticks can survive in sub zero temperatures and then when brought back to room temperature, they can continue on with their life as if nothing happened, sort of like Walt Disney's wish Okay ber Bye, Is that true.
Can you freeze them and then they pop back?
They can, I mean for short periods of time. They couldn't do it for very long. They're much more humidity sensitive than they are temperature sensitive, so they can tolerate a wide range of temperatures as long as they have the right humidity. They probably couldn't live in a freezer for very long, but you could probably put them in there for you know, maybe up to a day, half a day, I don't know, and they might still be alive afterwards, especially the adults, they can be a little heartier.
Don't advocate these sort of experiments at home.
And one last patroon question one paid Ro Martinez wants to know how does the tick affect the deer? An if you eat deer meat, can you get lime from it?
So that's a really good question.
We don't really know how how an if deer are affected by the pathogen. There's the evidence of it is that the deer actually are not really good reservoirs. They don't maintain an infection. They may actually fight off the infection, similar to how lizards do that. But there are you know, there aren't a lot of studies that have really dived into this with deer just because they're kind of hard
to work with. But the evidence is that they actually are probably not a really important source of infection for the tick population and probably are able to fight it off.
Wow. Okay, so I look this up and again, according to the CDC, you will not get lime disease from eating venison or squirrel meat. And now, last two questions that I always ask are what is one thing that's just the worst about what you do anything?
So I have a couple of things that really suck. Probably the worst is poison oak. So doing field work the poison oak in California is a big hazard. You know, people can get really.
Sensitive to it.
I've had students go to the hospital because of their reaction to it. And that's where the ticks like to be, right underneath that poison oak. And so you know, sometimes if we're sampling, we have.
To go through it. You just have to dive in and.
Pray, pray for the best. The other thing that is really unpleasant is with trapping small mammals. Sometimes predators will find the traps and then they leave us a nice juicy dismembered body or something like that. And so that's that's pretty unpleasant as well.
And now usually when you're if you're sampling a little rodent, are you able to sample it and let it out or do you have to take it into the lab with you and it's game over for the little mouse?
Oh nos.
Most of the animals we sample in the field, we process them in the field and release them. Oh nice, So we're yeah, so we're really interested in sort of how it's maintained in natural populations.
And so this way we can go.
Back year after year, you know, we know, you know, oh this is a two five nine to one. We caught him last year and he was infected. Is he infected this year? And so we can look at those long term population trends with this sort of data.
Nice.
So they're like, oh, yes, it's peanut butter oats season. They're like, I remember, this is delicious. There might maybe not the mice that learn super fast.
Yeah, no, they are not trap averse.
There are some species that you really have to coax them in. This is why it's really hard to work on Western gray squirrels, which are also a potential reservoir or they are a reservoir of lime disease in California, but we could not get them into our traps. They just or you know, they stay away. But a lot of the other are the mice and the wood rat. They're happy to spend a night in our little peanut butter hotel, and so we have no problems coaxing them in.
I would stay in that hotel easily if it was just filled with peanut butter opalls. It'd be like check, yeah, Pierce my ear, I'm exactly see you next year. And then what is your favorite thing about what you do and about science or about working with tickboard illnesses?
Honestly all of it. I mean, I just love like every aspect of it.
And unfortunately I don't have a lot of time to do it myself these days, and so you know, when I do do have more time, it's just I'm thrilled, you know. I get to go into the field and I get to work with my students and catch animals and bring the ticks back. And I love looking at stuff under the microscope still, so whether it's the bacteria or the ticks themselves.
You know, we collect thousands of.
Ticks and every single one has to be identified, you know, I get a lot of help from my students who do a lot of that work, but I love to get under there as well, under the microscope and see what we found. And you know, they are really intricate and interesting when you look at them under nine hundred X.
Do you have a microscope at home too, just for funzis?
I have a really crappy one that's like a kid toy one, but I've been toying with the idea of bringing home a better one, just because there's lots of fun stuff to see at home too.
Yeah.
I was thinking, like, there's so many people that have like a record player at home for vinyl, which is great, but I feel like if everyone had a microscope at home, it's kind of like just unlimited entertainment, you know, especially if your Netflix is down or something, you just put anything under there.
Oh yeah, I totally agree. In fact, I'm going to bring a microscope home.
Thank you so much for talking to me over Skype. I turned off the air conditioning in my house because it was too loud, and I'm sorry, I'm just melting like a candle and I'm not much to look at.
But thank you for being so patient.
Of course, this is so fun.
Say hi to the ticks, and by hi, I mean tell them I hate them.
Yeah, I'll put them in methan off for you.
So maybe treat yourself or a loved one to an affordable microscope and ask smart people stupid questions because it just might save your body the trouble of fighting off something nasty and you the trouble of having to crowdfund medical treatment. So more info on doctor Andrea Sway's work is at Sway lab dot com Swei lab dot com. You can keep up to date with her science badassery
on Twitter at Sway Lab or at Andrea Sway. I'm going to put links to those in the show notes, as well as sponsor links, the nonprofit links and more links and info is always up at aliward dot com, slash ologies, it'll be aliword dot com, slash Ologies, slash disease Ecology. I am on Twitter and Instagram at Ali Ward with one L. The show is on both at ologies.
You can say hi.
You can tag your merch photos with hashtag ologies merch or artwork at hashtag Ology's art I love to see and repost him. Merch is available at ologiesmerch dot com Thank you to sister Shannon Feltus and Bonnie Dutch for managing that and do you check out their brand new podcast You Are That.
New episodes drop on Mondays. The first episode last week featured.
Melotologist Amanda Shaw and it was a goddamn delight. Thank you to Aaron Talbert and Hannahlippo You Wonderful Beings for admitting the Ologies podcast Facebook group. Thanks to everyone who signed up on patreon dot com slash Ologies. Thank you to the very handsome Jared Sleeper of mind gam Media and the podcast My Good Bad Brain. He also has a martial arts podcast, Fight Stuff. He helps with assistant editing and helped me move last week amid a very
busy month. You were amazing and of course huge thanks to editor Stephen Ray Morris, who hosts the per cast about Kiddies and c Jurassic Right, which is about Dino's He stitches us all together each week always saves the day. The theme song was written and performed by Nick Thorburn of the band Islands And if you listen to the end of the show, you know I tell you a secret. And this week I realized that when I turned my phone to airplane mode, I get approximately one million percent
more work done. So thank you to Jared Sleeper for that suggestion. He was like, why don't you just turn your phone on airplane mode? And I was like, that's not gonna work. And then I was like, oh my god, I got so much done. How is this possible? I need a brain ologist to explain what happens when brain thoughts are interrupted and why it takes so long to
get back on track. Also, if I'm slow to return anyone's texts, please know it's just because I'm busy getting a chess tattoo that says airplane motor die in very ornate font. Okay, remember check those crevices, my wonderful friends and ticks. If you're listening, I respect your very effective life cycles, your thousands of children and one go. I think your knive mouths are amazing. Your thirst for horror is just so edgy. But still I fucking hate you
so much to leave my bathing suit areas alone. Okay, have fun out there. Check your crevices, per pie pacodermatology, hobbiology or doo zoology, lithology, technology, meteorology, mettology, menthology, zeriology, eldology, I got