What are senolytics (and should you be taking them)?

These compounds are said to fight aging by clearing “zombie cells” out of your body. Is there any science to back this up?

References

Effects of intermittent senolytic therapy on bone metabolism in postmenopausal women: a phase 2 randomized controlled trial - PubMed

A pilot study of senolytics to improve cognition and mobility in older adults at risk for Alzheimer’s disease - ScienceDirect

JCI - Strategies targeting cellular senescence

Targeting senescent cells: approaches, opportunities, challenges - PMC

Targeting cellular senescence with senotherapeutics: senolytics and senomorphics - Zhang - 2023 - The FEBS Journal - Wiley Online Library

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