NEJM AI Grand Rounds - podcast cover

NEJM AI Grand Rounds

NEJM Groupai-podcast.nejm.org
NEJM AI Grand Rounds, hosted by Arjun (Raj) Manrai, Ph.D. and Andrew Beam, Ph.D., features informal conversations with a variety of unique experts exploring the deep issues at the intersection of artificial intelligence, machine learning, and medicine. You’ll learn how AI will change clinical practice and healthcare, how it will impact the patient experience, and about the people who are pushing for innovation. Whether you are an AI researcher or a practicing clinician, these conversations will enlighten and surprise you as we journey through this very exciting field. Produced by NEJM Group.
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Episodes

Machines & Genes: The Future of AI in Biology with Dr. George Church

In this episode, vanguard geneticist Dr. George Church recounts his storied career from his early fascination with computers and science to his pioneering work in genomics and synthetic biology. Dr. Church developed innovative DNA sequencing methods that enabled the first sequencing of the human genome. He was also instrumental in developing CRISPR gene editing technology. Dr. Church discusses his controversial ideas around resurrecting wooly mammoths and using genome sequencing in dating apps t...

Oct 25, 202350 minEp. 11

Mark Cuban on AI, Trust in Health Care, and Skip Bayless

In this episode, we’re joined by business magnate and investor Mark Cuban . Cuban describes his journey from humble beginnings as a self-taught programmer to becoming a successful serial entrepreneur and owner of an NBA team. Cuban shares the founding story of his pharmacy benefits company, Cost Plus Drugs, and his vision for reimagining the reimbursement system for care. He also articulates why he believes AI will be more transformative than prior technology shifts such as mobile and the intern...

Sep 27, 20231 hr 8 minEp. 10

An Iron Fist in a Velvet Glove: A Conversation with Dr. Atul Butte

In this episode, pioneering informatician Dr. Atul Butte guides listeners through his storied career, from his early days as a pediatric endocrinologist and informatician in Boston to his trailblazing work on the West Coast. Dr. Butte describes his trailblazing efforts to both harness large-scale public biomedical data and share patient data across the entire UC Health System. Dr. Butte also discusses his entrepreneurial journey, including the genesis and vision behind companies like NuMedii. Dr...

Aug 23, 20231 hr 17 minEp. 9

The Double-Edged Sword of AI, with Dr. Ziad Obermeyer

In this thought-provoking episode, Dr. Ziad Obermeyer delves into the complex issues of bias, safety, and generalizability of medical AI. Dr. Obermeyer emphasizes the importance of machine learning researchers’ task formulation, an often-overlooked yet significant determinant of bias in AI algorithms. Highlighting the dual impact of machine learning, he compares two of his works that demonstrate how AI can either exacerbate or help mitigate health care disparities. Lastly, he discusses the signi...

Jul 27, 20231 hr 14 minEp. 8

Can AI Be Harmful? A Conversation with MIT’s Dr. Marzyeh Ghassemi

Dr. Marzyeh Ghassemi has been at the forefront of medical machine learning for several years. In this episode, she describes her group’s work and her perspectives on developing and applying machine learning to understand and improve health in ways that are robust, private, and fair. Dr. Ghassemi is an Assistant Professor at MIT in Electrical Engineering and Computer Science and the Institute for Medical Engineering & Science. Transcript...

Jun 28, 20231 hr 12 minEp. 7

Google’s Exploration of Large Language Models in Medicine

Large language models (LLMs) like ChatGPT have proven highly capable of a broad array of natural language tasks including summarizing text, generating prose, and answering questions. This episode’s two guests, Dr. Alan Karthikesalingam and Vivek Natarajan of Google, describe their team’s recent efforts to adapt and evaluate LLMs for clinical applications. Alan and Vivek took very different paths to becoming leading medical AI researchers and in this episode they also share their educational jour...

May 24, 20231 hr 7 minEp. 6

No Doctor Needed? Dr. Michael Abramoff on the Potential of Autonomous AI

Dr. Michael Abramoff is a renowned ophthalmologist and medical AI pioneer. In this episode, we explore his groundbreaking work that led to the first FDA-authorized device that does not require a physician, IDx-DR, which detects more than mild diabetic retinopathy from digital images of the eye. Dr. Abramoff also reflects on the challenges of commercialization, AI reimbursement, and the ethical imperatives for AI in health care centered around patient benefit. Dr. Abramoff is the Robert C. Watzke...

Apr 26, 20231 hr 5 minEp. 5

The GPT-4 Episode: Microsoft’s Peter Lee on the Future of Language Models in Medicine

Dr. Peter Lee has shaped computer science from academia, government, and industry. He has chaired a major computer science department, built a new technology office at DARPA, and now serves as Corporate Vice President at Microsoft, where he leads Microsoft Research and its nine worldwide laboratories. In this episode, Peter reveals Microsoft’s interest in health care and the origins of the OpenAI and Microsoft partnership, and he speculates on how large language models like ChatGPT will transfor...

Mar 29, 20231 hr 16 minEp. 4

Dr. Lily Peng: AI for Ophthalmology and the Challenges of AI in the Real World

Dr. Lily Peng has driven major medical AI efforts along the long and arduous path from ideation to deployment. From publishing a landmark study in 2016 presenting an AI model to detect diabetic retinopathy in retinal fundus photographs to evaluating deep learning systems in India and Thailand, she has a unique and wide-ranging perspective on both model development and real-world validation. She continues to lead medical AI efforts as a physician-scientist and the Director of Product Management a...

Feb 15, 20231 hr 7 minEp. 3

Dr. Pranav Rajpurkar on AI and Radiology

Dr. Pranav Rajpurkar has been at the forefront of medical AI for his entire career. As a graduate student in computer science at Stanford, he created some of the first AI models for radiology and created a suite of datasets and benchmarks that have been widely used by researchers across the world. Now, as a faculty member at Harvard, his group has continued to push the frontier of medical AI across many different specialties including radiology, pathology, and cardiology. Transcript...

Jan 18, 20231 hr 13 minEp. 2

Dr. Euan Ashley on AI, Genomics, and Cardiology

Dr. Euan Ashley is a pioneer. In 2010, he led the team that conducted the first clinical interpretation of a human genome, and he holds the record for the world’s fastest genomic diagnosis. He even has a Guinness World Record to prove it. In this wide-ranging discussion, Dr. Ashley shares the stories behind these feats, his experiences applying artificial intelligence to genomics and to cardiology, and his views on whether and how AI will change medicine. Transcript...

Dec 15, 202255 minEp. 1

Trailer: Introducing NEJM AI Grand Rounds Podcast

[Transcript] How will AI change clinical practice and healthcare, and how will it impact the patient experience? Who are the people pushing for change and what are their goals? These are just a few of the topics that we hope to explore on NEJM AI Grand Rounds , a new podcast from NEJM Group. This podcast will be an informal conversation with a variety of unique experts exploring the deep issues at the intersection of artificial intelligence and medicine. Whether you are an AI researcher or a pra...

Dec 05, 20222 min
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