Naked Genetics, from the Naked Scientists - podcast cover

Naked Genetics, from the Naked Scientists

From plants to pathogens, fruit flies to fungi and hamsters to humans, Naked Genetics takes a look at the science of genes. With in-depth interviews and the latest discoveries from the world of genetics, tune in for a look inside your genes...

Episodes

CRISPR: the cutting edge of gene editing

In this edition of Naked Genetics, we take a closer look at CRISPR gene editing. What is it? And what are the ethics involved in rewriting the human genome? Like this podcast? Please help us by supporting the Naked Scientists

Mar 12, 202530 minEp. 109

Debunking 'junk' DNA

In this episode of Naked Genetics: What new DNA techniques are revealing about human sacrifices in Mayan culture; we debunk the 'junk', in junk DNA; and, the upside down sea snail that makes rafts of its own snot... Like this podcast? Please help us by supporting the Naked Scientists

Dec 09, 202433 minEp. 108

Will It Sequence? Synthetic DNA

In this episode of Naked Genetics: How much of your personality is down to your DNA; we also look at synthetic DNA, and why we'd want to make it; plus, the spiders that turn one species of insect against its own kind... Like this podcast? Please help us by supporting the Naked Scientists

Oct 09, 202425 minEp. 107

Will It Sequence? 700-year-old DNA

In this episode of Naked Genetics: A mammoth discovery in ancient DNA structure; on the subject of ancient DNA, what can we sequence for a centuries old body? And, in quirks of evolution, the animal that drinks its own offspring's blood... Like this podcast? Please help us by supporting the Naked Scientists

Aug 23, 202421 minEp. 106

Will It Sequence: How effective is handwashing?

In this episode of Naked Genetics: The risk factors between schizophrenia and substance use disorder have had a fresh genetic examination; I put Illumina to the test and ask, 'what difference does washing our hands really make?' And, the the extraordinary way in which dung beetles use the night sky to orientate themselves... Like this podcast? Please help us by supporting the Naked Scientists

Jul 16, 202419 minEp. 105

Will It Sequence? What grows on your food?

In this episode of Naked Genetics: What the latest genetics research has to say about restless leg syndrome; I put Illumina to the test and ask, 'what really grows on our food?'; And, what makes a tardigrade so tough? Like this podcast? Please help us by supporting the Naked Scientists

Jun 07, 202425 minEp. 104

Will It Sequence? Hunting drug resistant bugs

In this month's edition of Naked Genetics: Why a genetic bottleneck created decades ago means some whales are in deep water; how wastewater is helping genetic sequencer track down deadly diseases; And, surf's up! how one beach dwelling creature is shredding the gnar in order to find food... Like this podcast? Please help us by supporting the Naked Scientists

May 03, 202423 minEp. 103

ADHD advantages, and mining microbiomes

This episode of Naked Genetics: has the evolutionary advantage to ADHD been uncovered? Also, We look at the microbiome of mining. And, the only vertebrate in the world that would thank you for saying that it looked like crap... Like this podcast? Please help us by supporting the Naked Scientists

Apr 05, 202423 minEp. 102

The roamin' Roman Empire, and Charles Darwin's love life

In this edition of Naked Genetics: The surprising findings of a roman empire diversity study; Are hybrid animals the way out of the biodiversity crisis? And, was charles darwin as romantic as he was scientifically brilliant? Like this podcast? Please help us by supporting the Naked Scientists

Feb 28, 202429 minEp. 101

The origin of Europe's MS disease, and South Pole sequencing

This episode of Naked Genetics, the origins of multiple sclerosis markers in northern Europe is revealed, and why it might have helped more people than it hindered; we also look at organisms surviving in Earth's most extreme conditions; and ask just why might a bunch of organisms be turning into crabs? Like this podcast? Please help us by supporting the Naked Scientists

Jan 22, 202428 minEp. 100

Testing for genetic diseases, and bats with big penises

This episode of Naked Genetics, we catch up with our genetics experts and look into the hot button genetics news; we look at how genetics affects our genes, and how genes affect our ageing; and, another extraordinary mating ritual in Quirks of Evolution... Like this podcast? Please help us by supporting the Naked Scientists

Dec 15, 202328 minEp. 99

Is vegetarianism genetic, and the penis-eating spider

This episode, we catch up with some of the more curious genetics news from the past month including how much Neanderthal is in you and how that affects your risk of disease. Also, we look at one of the most remarkable breeding strategies in the animal kingdom, a spider with two penises that eats one of them... Like this podcast? Please help us by supporting the Naked Scientists

Nov 14, 202331 minEp. 98

COVID In Your Genes: The Risk Factors

Do our genes control how we respond to COVID? The question has been nagging at the world since the pandemic began. Now we have the answer - and it's yes. In this programme, geneticist Nathan Pearson uncovers the specific bits of DNA that make you more likely to catch coronavirus, as well as the bits that might make you sicker.... Like this podcast? Please help us by supporting the Naked Scientists

Apr 14, 202130 minEp. 97

The Genes Who Came in for the Cold

How do we cope at the extremes of low temperature? Across the world, groups of people have historically made their home in icy and inhospitable landscapes... and even today, groups of thrill seekers push their bodies to the limits by going swimming in water close to freezing. In this month's programme, genes that help us handle - and even enjoy - being very cold. We've got two stories from the ancient ice, including the oldest ever DNA; plus, two modern genes found to be helping us out in intere...

Mar 17, 202130 minEp. 96

How To Tell Coronavirus Variants Apart

We're looking at the most critical variants of the coronavirus, and finding out how to tell whether they're flummoxing COVID vaccines. Plus: the cost of catching a serial killer; DNA with four strands instead of two; and a mutant fish whose fins have started turning into limbs! Like this podcast? Please help us by supporting the Naked Scientists

Feb 24, 202129 minEp. 95

Identical Twins: Not Identical?

Meet the small DNA differences that make their mark by existing in the magical period of early development. We'll hear how mutations in the very first stages of human embryos have bizarre consequences for identical twins; and how even earlier in the process, sperm use selfish genes to get ahead of the competition. Plus, an immunologist untangles mRNA COVID vaccines, from efficacy numbers to delayed booster shots... Like this podcast? Please help us by supporting the Naked Scientists...

Jan 15, 202129 minEp. 94

RNA vaccines, privacy, and penguins

The first group of people in the world have received a 'genetic' vaccine against the coronavirus. What is it, and how does it work? Naked Scientist Chris Smith breaks it down and addresses your concerns. Plus, why some genes have to change rapidly just to stay the same; a new way to keep functional genetic information private; and three new species of penguin arrive on the scene... Like this podcast? Please help us by supporting the Naked Scientists...

Dec 17, 202024 minEp. 93

Mink, Ivory, & a Disease Discovered Backwards

It's a regular Noah's Ark: from the coronavirus strains that have been spreading through minks, to a new DNA test that can track poached elephant ivory, to the genetics of a very useful - and very inbred - cat. Plus: scientists have discovered a brand new genetic disease, via an unlikely approach and an even unlikelier coincidence... Like this podcast? Please help us by supporting the Naked Scientists

Nov 13, 202027 minEp. 92

Slave Trade, Neanderthals, & COVID

This week: a risk factor for severe COVID that comes from Neanderthals; using genes to track the millions transported as slaves across the Atlantic; a doctor runs through the list of what coronavirus mutations are worth watching out for; and learning population genetics from a video game... Like this podcast? Please help us by supporting the Naked Scientists

Oct 16, 202028 minEp. 91

How To Survive Poison

This week, a message from Naked Scientists listener Loretta. "I'm curious if your show might cover some of the most interesting case studies of organisms developing tolerance to severe toxins, what genetic insight this gives us about adaptation and natural selection more broadly, and what some of the tradeoffs might be when evolving to have such tolerances." We're answering her question: how do animals - and even humans - eat poison, and get away with it? Like this podcast? Please help us by sup...

Sep 14, 202030 minEp. 90

The Inner Lives of Birds

Tweet tweet! We're talking birds, and the incredible things they can do. Today we're spotlighting five of the coolest recent stories in bird genetics: hummingbirds powering their lightning-fast flight; a gene that controls migration; why males have different colours to females; how light pollution makes sparrows sicker; and the bird trapped for thousands of years under the Siberian ice... Like this podcast? Please help us by supporting the Naked Scientists...

Aug 19, 202029 minEp. 89

Female Mosaicism: The Stronger Sex?

The same thing that makes the patchwork colours on a tortoiseshell cat, also - according to some - is why human females live longer, see colour better, and even more often survive the coronavirus. It's all thanks to having two X chromosomes. Females compensate by switching one of them off, and the result is two distinct groups of cells in the body, each preferring one of the two X's. Welcome to the weird world of female mosaicism... Like this podcast? Please help us by supporting the Naked Scien...

Jul 15, 202027 minEp. 88

Fermented foods: the real deal?

We take a look at the trendy world of fermented foods. Are they actually good for you? And if so, why? Plus, the latest genetics news: from bacteria that live inside cancer cells, to gene sequencing the dead sea scrolls... Like this podcast? Please help us by supporting the Naked Scientists

Jun 15, 202030 minEp. 87

ACE2: The Coronavirus Gateway

Are you one of the many people who take ACE inhibitors or ARBs to treat high blood pressure? Or to help with heart issues or diabetes? In the UK, this is about one in seven people, making these are some of the most common prescription drugs out there; and recently there have been worries that they might make a coronavirus infection worse. The link between the drugs and the virus is a molecule inside everyone's bodies called ACE2. On today's show, meet ACE2, the protein in the spotlight: the bast...

May 14, 202034 minEp. 86

The Coronavirus Mutation Situation

In this episode we're taking apart the tiny creature behind this global pandemic. From how looking at the genes of the coronavirus can help figure out the animal it comes from; to the exact ways it's spreading around the world; and even how a hidden mutation is threatening to lead vaccine-makers on a wild goose chase. Plus, Gins & Genes goes virtual; stay tuned to hear what's inside our guest's downstairs toilet... Like this podcast? Please help us by supporting the Naked Scientists...

Apr 15, 202025 minEp. 85

Gene Genealogy & The Lost Family

One of the biggest tech booms of the past half decade has been direct to consumer DNA tests. The results come in the post, and with them come both answers and new questions: questions that tens of thousands of people now have to figure out how to ask. In this episode, a new book from journalist Libby Copeland about a sociological phenomenon and its effects, both grand and intimate... Like this podcast? Please help us by supporting the Naked Scientists...

Mar 14, 202024 minEp. 84

FOXG1 Syndrome: Fighting the Odds

Listener Vivek got in touch with a question about a rare genetic disease his son has, called FOXG1 Syndrone. In fact, it's so rare - and so newly-discovered - that only about six hundred people in the world have been diagnosed. Kids with FOXG1 have severe developmental delays; in Vivek's words, "everything that can go wrong - it's gone wrong with him." But the parents of FOXG1 children have been unusually tenacious when it comes to shaping the course of science. In this programme we meet those p...

Feb 20, 202025 minEp. 83

The Fly Infest-agation

We got a Christmas present from listener Anna: a small plastic tube full of dead flies. They've recently been infesting the hospital where she works. She wants us to figure out what they are, and what caused the infestation. Can DNA crack the case? Plus, the return of Gins & Genes... Like this podcast? Please help us by supporting the Naked Scientists

Jan 14, 202028 minEp. 82

African genetics and ethics

There are very few African studies in genetics. And on the whole, there is a big European bias in the field. In Europe there are resources of hundreds of thousands of individuals' data, like the UK Biobank, and so that's where most research take place. But there's a potential problem: the subtle differences in DNA may start to make a difference the more genetics is used to diagnose and treat diseases. All this is why a number of institutions have collaborated to survey thousands of people's geno...

Dec 14, 201929 minEp. 81

What's in the water?

This month we're diving into the stuff that makes up two thirds of the Earth's surface. Can you use genetics to figure out what's in the water? We put the science to the test by making a geneticist guess our mystery fish. Plus, a story about whales and dolphins: what do you lose when you leave the land? Jump in, the water's fine. Like this podcast? Please help us by supporting the Naked Scientists

Nov 14, 201926 minEp. 80
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