Here Dr Ryan Rossner of Minicircle talks about plasmid gene therapy. We get into what it is, how it works, why it is simpler than viral vector gene therapy and look at some of the results that they have seen. 🌐Links in this video Minicircle website https://minicircle.io/ Plasmid delivery of follistatin gene therapy safely improves body composition and lowers extrinsic epigenetic age in sex- and age-diverse adult human subjects https://minicircle.io/wp-content/uploads/2024/04/fstpreprint.pdf X h...
Jul 07, 2025•38 min•Season 100Ep. 45
Here Dr Ben Lynch, author of Dirty Genes talks about what SNPs are, how they effect us but also why they do not define our destiny and what we can do about them. We dive into detail on histamine intolerance. 🌐Links in this video Dr Lynch's website https://www.drbenlynch.com/ Malacards https://www.malacards.org/ Gene Cards https://www.genecards.org/ Dirty Genes: A Breakthrough Program to Treat the Root Cause of Illness and Optimize Your Health https://amzn.to/3SIYP98 Dirty Genes Histamine Workbo...
Jun 30, 2025•1 hr 10 min•Season 100Ep. 44
Here Michael Bush, talks about how to identify what probiotics could be helpful to you and how to identify ones that will work. We also look at the future where there are probiotics protecting you from kidney stones and producing GABA to make you less stressed! 🌐Links in this video Michael Bush's current organization https://www.growthways.com/home0-1 International Probiotics Association https://internationalprobiotics.org/home/ International Scientific Association of Probiotics and Prebiotics ...
Jun 23, 2025•1 hr 2 min•Season 100Ep. 47
DESCRIPTION Here Dave Watumull of AX3 Life takes us through the amazing properties of astaxanthin. It is a powerful antioxidant and anti-inflammatory and the only supplement to show a greater than 10% increase in lifespan in the ITP trials. Here we dive into the chemistry, trial results and benefits of the molecule 🌐Links in this video AX3 Life web site : https://ax3.life/ AX3 Instgram https://www.instagram.com/ax3.life ITP Paper including Astaxanthin: Astaxanthin and meclizine extend lifespan ...
Jun 16, 2025•1 hr 11 min•Season 100Ep. 42
In this video, I interview Dr Ross Walker a leading cardiologist with 40 years’ experience and Consultant Cardiologist & Chairperson of Gut Foundation Australia. We talk about the importance of our microbiome, how it has such a large impact on many areas of our physical and mental health and what we can do to improve it. Links in this video: The Gut Foundation of Australia https://gutfoundation.com.au/ *Thanks to our Sponsor* Theronomic by Wellizen. www.theronomic.com...
Jun 09, 2025•30 min•Season 100Ep. 41
Here Dr Joy Kong talks about stem cells, their amazing properties and how they can be used in medicine. 🌐Links in this video Dr Kong's Home page https://joykongmd.com/ Chara Health https://chara-health.com/ Instagram https://www.instagram.com/dr_joy_kong/ Dr Kong YouTube channel https://www.youtube.com/@JoyKongMD https://www.choosemuse.com All Muse devices 15% discount code MODERN https://choosemuse.com/MODERN Stemregen 15% discount Code MODERN https://tinyurl.com/45z968yr (Only available in th...
Jun 02, 2025•52 min•Season 100Ep. 40
Here Dr Michael Lustgarten from Conquer Age or Die Trying talks about the approach that has put him head of the leader board on the Longevity World Cup. We also dive into aging clocks, rapamycin and upcoming technologies. 🌐Links in this video Dr Lustgarten's YouTube channel https://www.youtube.com/channel/UCT1UMLpZ_CrQ_8I431K0b-g His home page https://michaellustgarten.com/ The Longevity World Cup https://longevityworldcup.com/ https://www.choosemuse.com All Muse devices 15% discount code MODER...
May 26, 2025•1 hr 3 min•Season 100Ep. 38
In this video, I interview Greg Macpherson, founder of SRW Laboratories, about their revolutionary supplement system, Cel System. Developed to address the hallmarks of ageing, SRW Laboratories have recently been published in the Aging Journal US (https://www.aging-us.com/article/206221/text), demonstrating measures to show reversal in biological age with clinical study participants. Greg explains the core principles behind their supplements and how they target the fundamental processes of ageing...
May 19, 2025•18 min•Season 100Ep. 38
Here Dr Robbins discusses what are the active factors in exosomes which help them to work their magic and cause systemic rejuvenation. This is the next step to making a reproducible therapy. 🌐Links in this video https://www.choosemuse.com All Muse devices 15% discount code MODERN https://choosemuse.com/MODERN Stemregen 15% discount Code MODERN https://tinyurl.com/45z968yr (Only available in the US) Renue by Science all 10% discount with code MHS https://renuebyscience.com/ Nuchido Time+ 20% dis...
May 13, 2025•1 hr 3 min•Season 100Ep. 37
Here Ariel Garten introduces the new Muse S Athena with added near infrared light sensors and how these detect blood flow in the brain to determine how hard it is working. She also talks about new features in the app for sleep tracking and monitoring alpha waves. 🌐Links in this video https://www.choosemuse.com All Muse devices 15% discount code MODERN https://choosemuse.com/MODERN Stemregen 15% discount Code MODERN https://tinyurl.com/45z968yr (Only available in the US) Renue by Science all 10%...
May 06, 2025•49 min•Season 100Ep. 36
Here Dr Tara Walker talks about the latest research on how exercise impacts the brain and what the best exercise forms are to protect your cognitive ability as you age. 🌐Links in this video Dr Walker's page at the Queensland Brain Institute https://qbi.uq.edu.au/dr-tara-walker The paper "Neuroprotective mechanisms of exercise and the importance of fitness for healthy brain ageing" https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)00184-9/abstract Stemregen 15% discount Code MOD...
Apr 28, 2025•48 min•Season 100Ep. 35
Here Dr Thomas Levy talks about the amazing power of Vitamin C as an antioxidant with amazing beneficial capabilities. We also discuss the other supplements in his Top 8 for cellular and mitochondrial health 🌐Links in this video Dr Levy's website https://www.tomlevymd.com/ Stemregen 15% discount Code MODERN https://tinyurl.com/45z968yr (Only available in the US) Renue by Science all 10% discount with code MHS https://renuebyscience.com/ Nuchido Time+ 20% discount of first purchase with code MOD...
Apr 21, 2025•1 hr 6 min•Season 100Ep. 34
Here Sebastian talks about rejuvenating the immune system with HSC transplants, how this can be done and the benefits. He proposes a model of proactive immune system renewal. We then talk about LongBio & wider progress to rejuvenation therapeutics. 🌐Links in this video ImmuneAge Bio https://immuneage.bio/ Healthspan Capital https://www.healthspancapital.vc/ Sebastian on LinkedIn https://www.linkedin.com/in/sebastianlongbio/ Stemregen 15% discount Code MODERN https://tinyurl.com/45z968yr (On...
Apr 16, 2025•57 min•Season 100Ep. 33
Here Dr Kidd talks about phosphatidylserine the benefits it provides as shown by RTCs. Although not approved, it even seems to have a blessing from the FDA. 🌐Links in this video ProHealth 15% discount code MODERN 300mg Phosphatidylserine https://prohealth.pxf.io/jem5ab Stemregen 15% discount Code MODERN https://tinyurl.com/45z968yr (Only available in the US) Renue by Science all 10% discount with code MHS https://renuebyscience.com/ Nuchido Time+ 20% discount of first purchase with code MODERN2...
Apr 09, 2025•1 hr 5 min•Season 100Ep. 32
Here Dr Holick talks about Vitamin D3, how much we need and why it is so important for the bone health and the immune system. 🌐Links in this video Dr Holick's website https://drmichaelholick.org/ Vitamin D information https://drmichaelholick.org/vitamin-d/ Dr Holick's page at Boston University https://www.bumc.bu.edu/camed/profile/michael-holick/ Stemregen 15% discount Code MODERN https://tinyurl.com/45z968yr (Only available in the US) Renue by Science all 10% discount with code MHS https://ren...
Apr 01, 2025•58 min•Season 100Ep. 31
Here Liz talks about her personal experience with gene therapy and the innovations, the state of the industry and what the future holds. The therapies exist why is it so difficult to make them available! 🌐Links in this video BioViva Home Page https://bioviva-science.com/ BioViva on LinkedIn https://www.linkedin.com/company/biovivasciences/ Liz on X https://x.com/parrishliz BioViva on X https://x.com/BioVivaScience Stemregen 15% discount Code MODERN https://tinyurl.com/45z968yr (Only available i...
Mar 17, 2025•1 hr 2 min•Season 100Ep. 30
Here Liam and Will from Neuronic talk about their red light devices, the cognitive benefits and science and why they chose to use 1070 nm red light. 🌐Links in this video Neuronic Devices $100 Discount Coed MODERN100 https://tinyurl.com/y5u4rybw Stemregen 15% discount Code MODERN https://tinyurl.com/45z968yr (Only available in the US) Renue by Science all 10% discount with code MHS https://renuebyscience.com/ Nuchido Time+ 20% discount of first purchase with code MODERN20 https://nuchido.com/MOD...
Mar 11, 2025•46 min•Season 100Ep. 29
Here Dave Pascoe talks about his exercise, experience with exosomes and stem cells and his systems for managing his data. 🌐Links in this video Dave's website https://www.davepascoe.net/home On Instagram https://www.instagram.com/dave.pascoe Oxford Healthspan Spermidine 15% discount Code MHS Original https://tinyurl.com/hrxfnzpn, Gluten Free https://tinyurl.com/2s39pkzv Stemregen 15% discount Code MODERN https://tinyurl.com/45z968yr (Only available in the US) Renue by Science all 10% discount wi...
Mar 04, 2025•47 min•Season 100Ep. 27
Here Dave Pascoe talks about his protocol and some of his philosophy behind it. The interview ran to two hours so I have split it into two parts. 🌐Links in this video Dave's website https://www.davepascoe.net/home On Instagram https://www.instagram.com/dave.pascoe Oxford Healthspan Spermidine 15% discount Code MHS Original https://tinyurl.com/hrxfnzpn, Gluten Free https://tinyurl.com/2s39pkzv Stemregen 15% discount Code MODERN https://tinyurl.com/45z968yr (Only available in the US) Renue by Sci...
Feb 24, 2025•1 hr 11 min•Season 100Ep. 26
Here Leslie Kenny talks about the benefits of spermidine and the science behind it, while also sharing her personal health journey 🌐Links in this video Website https://oxfordhealthspan.com/ Instagram https://instagram.com/oxfordhealthspan LinkedIn https://www.linkedin.com/company/oxford-healthspan/ Oxford Healthspan Spermidine 15% discount Code MHS Original https://tinyurl.com/hrxfnzpn, Gluten Free https://tinyurl.com/2s39pkzv Stemregen 15% discount Code MODERN https://tinyurl.com/45z968yr (Onl...
Feb 17, 2025•1 hr 22 min•Season 100Ep. 25
Here Dr Lanna talks about his work in rejuvenating the immune system by rescuing senescent T--cells. 🌐Links in this video Sentcell website https://sentcell.life/ Some of Dr Lanna's published papers An intercellular transfer of telomeres rescues T cells from senescence and promotes long-term immunological memory https://pubmed.ncbi.nlm.nih.gov/36109671/ Rejuvenation driven reprograming in T lymphocytes https://www.researchgate.net/publication/384821561_Rejuvenation_driven_reprograming_in_T_lymph...
Feb 12, 2025•45 min•Season 100Ep. 24
Here Dr Dror talks about the investment market for Longevity, who are some of the major players, what they are investing in and how it is different this time. 🌐Links in this video Investors in Longevity on Amazon https://amzn.to/4j2MSH8 Stemregen 15% discount Code MODERN https://tinyurl.com/45z968yr (Only available in the US) Renue by Science all 10% discount with code MHS https://renuebyscience.com/ Nuchido Time+ 20% discount of first purchase with code MODERN20 https://nuchido.com/MODERN If y...
Feb 04, 2025•1 hr 6 min•Season 100Ep. 24
Here Dr Jepsen talks about the work they are doing at Openwater, using a consumer technology focus to bring affordable precision solutions to healthcare with an open source approach. The potential for the platform that they are developing is amazing. 🌐Links in this video penwater web site. https://www.openwater.health/ Dr Jepsen's website https://www.maryloujepsen.com/ Dr Jepsen talking with Peter Gabriel https://www.youtube.com/watch?v=XvEU51XMH8o Stemregen 15% discount Code MODERN https://tin...
Jan 28, 2025•1 hr•Season 100Ep. 22
Here Dr Phillips talks about her system for overall oral healthcare, improving teeth, gums and the oral microbiome. 🌐Links in this video Dr Phillips' website https://drellie.com/ Stemregen 15% discount Code MODERN https://tinyurl.com/45z968yr (Only available in the US) Renue by Science all 10% discount with code MHS https://renuebyscience.com/ Nuchido Time+ 20% discount of first purchase with code MODERN20 https://nuchido.com/MODERN If you would like to support our channel please consider signi...
Jan 23, 2025•1 hr 24 min•Season 100Ep. 21
Here Dr Breus, the Sleep Doctor, talks about how sleep changes with aging and gives some advice on getting good quality sleep, using a sleep tracker and getting back to sleep after you wake up in the middle of the night. 🌐Links in this video Dr Breus' site https://sleepdoctor.com/ The Chronoquiz to find your chronotype https://sleepdoctor.com/sleep-quizzes/chronotype-quiz/ Sleep Drink Breathe: Simple Daily Habits for Profound Long-Term Health https://tinyurl.com/3hz5j5d2 Stemregen 15% discount ...
Jan 14, 2025•53 min•Season 100Ep. 20
Here we talk with Dr Adam Perlman the Chief Medical Officer of Pendulum Therapeutics about the microbiome and probiotics and their impact on metabolic health. We also look into the results from the clinical trials of the products 🌐Links in this video Clene Nanomedicine https://clene.com/ Stemregen 15% discount Code MODERN https://tinyurl.com/45z968yr (Only available in the US) Renue by Science all 10% discount with code MHS https://renuebyscience.com/ Nuchido Time+ 20% discount of first purchas...
Jan 07, 2025•41 min•Season 100Ep. 21
Here we talk with Dr Adam Perlman the Chief Medical Officer of Pendulum Therapeutics about the microbiome and probiotics and their impact on metabolic health. We also look into the results from the clinical trials of the products. 🌐Links in this Interview Pendulum Therapeutics page https://pendulumlife.com/ Improvements to postprandial glucose control in subjects with type 2 diabetes: a multicenter, double blind, randomized placebo-controlled trial of a novel probiotic formulation https://drc.b...
Dec 30, 2024•1 hr 2 min•Season 100Ep. 18
Here we talk with Professor Mark Tarnopolsky from McMaster University about mitochondria, what goes wrong with them in aging and how to he has used a multi-supplement approach to improve their function in aging and in case of disease. 🌐Links in this Interview Dr Tarnopolsky's nutrition shop. I think ships to US & Canada only https://stayabovenutrition.ca/ A selection of Dr Tarnopolsky's papers, including the trials he discussed in the interview Beneficial effects of creatine, CoQ10, and lip...
Dec 24, 2024•1 hr 7 min•Season 100Ep. 17
Here we talk with Don Moxley of Stemregen about how stem cells are critical for recovery and so determine your ability to train and positively adapt. We also discuss the new sport science function that he is setting up at Stemregen and using HRV in training. 🌐Links in this Interview Stemregen https://www.stemregen.co/ Don's LinkedIn https://www.linkedin.com/in/donmoxley/ Stemregen on Instagram https://www.instagram.com/stemregen/ Stemregen 15% discount Code MODERN https://tinyurl.com/45z968yr (...
Dec 16, 2024•1 hr 2 min•Season 100Ep. 17
Here we talk with Dr Bill Andrews all about telomeres, why they are on the critical path of aging and finding a way to lengthen them is required in an complete longevity solution. 🌐Links in this Interview Sierra Science home page https://sierrasci.com/ Dr Kaufmann's books on Amazon The Kaufmann Protocol : https://amzn.to/3YqpbPB The Kaufmann Protocol: Aging Solutions : https://amzn.to/3NJ2Oje BioViva Home page https://bioviva-science.com/ Touchstone Essentials https://touchstoneessentialsviraj....
Dec 11, 2024•1 hr 31 min•Season 100Ep. 14
