so today I want to talk about in reference to metabolic health , and you know , people are trying to do weight loss and they're trying to , you know , control what they're eating or or such , and people are prescribing medications such as ozempic , manjaro , um , there's , you name it . There are different ones out there that are excellent . Okay , they do work .
Yes , but until you understand the mechanism of action of medications or the need , these are not something that you do as a first line of a weight loss or when you're trying to understand your weight or understand why things are eating .
Now I'm going to share my screen because I feel that once you have some idea , maybe , maybe in that situation , you may change your thought process of what to take .
Now , I'm not one that will prescribe weight loss medications as a firsthand choice , because I'm much more into a functional and nutrition approach and changing your behaviors and learning what works for you . But the reason it's become this new thing on all of the social media platforms is because it's an easy fix .
Right , everyone goes oh my God , if you get a shot , you're going to totally lose weight . Why ? First off , I want you to understand what these medications are doing , so this is one of them that is so , initially , you want to know that you're .
It's called semaglutatide or GLP-1 , and its mechanism action is that 94% of the GLP-1s which it is a receptor agonist to the body , and it binds to that receptor , so that receptor stops the body from producing more glucose , and it kind of mediates that .
Then , in turn , though , is that it's albumin binding , it has issues with the renal clearance , and then it degrades your metabolism over time , as you can see here , and then what this says here is furthermore , the similatide stabilizes against degration of the DBP4 enzyme .
I'll go into that at another time , but major thing here that I want you to see is this drug , which is initially used for type 2 diabetes or really a metabolic health or pre-diabetic person , to stimulate insulin secretion and lowers glucagon or glucose dependent manner .
Now , yes , in turn it may lower your glucose , blood glucose , but it secretes more insulin , which then , in turn , can actually store more glucagon or release more insulin within the body . Yes , in turn it does cause a minor delay in gastric emptying . Now , the main thing people ask me is like oh wow , it's satay . Satay means it's a satisfying .
People don't feel like they want to eat as much they used to look at a plate of food and they would say I want to eat all of it and instead they now only want half of it or a small bite . It's because your body's mechanism of action at this time has been full and it thinks it's full and then you know it chooses not to eat .
But in this way , when you really look at it , there is so many other side effects that come with this and that's why it's not a medication that you're just going to say , hey , take it , let me lose all of this weight , because if you don't change your behaviors in the way of changing , so satay , it just means to satisfy it and so that you don't feel like
you need more . The main issues with this is that there's many of side effects with any medications . Will they be effective ? Yes , I will use them for some individuals , but until you , it's either this with an additional counseling and workaround and health coaching , because you need more than this .
A shot's not going to fix your behavior , the way that you think about food , your emotional eating response , and until the thought process and you learn that , unfortunately , these are not going to be those quick fixes . Are they amazing for the weight loss ? Yeah , because it stops you to eat and your stomach feels full . They call it gastric emptying .
But guess what ? Do you wanna see the amount of side effects that are contributed to this ? It is outstanding and kind of really serious . Like there's a black warning box on these medications that cause tumor C , so thyroid cancer and it's right here on the very top of it Risk for thyroid C cell tumors .
So that is a huge issue now and it's because this is an endocrine hormone medication . Glp-1 is affecting your hormones . So when you're improving , in sense , your glycemic number but in turn you're increasing your insulin within the body and then in turn you may have these other excess side effects , is it worth it ? So it's really about gain of positive .
Like most people have nausea . Gain of positive . Like most people have nausea , vomiting , diarrhea , abdominal pain , constipation . Do you want that on your regular day ? That's what you want , so that you can lose weight quickly . I just it's just not the correct way , because then your behaviors will change . Don't get me wrong .
There is times when I will prescribe this medication , but there's warning . You know . There's time and effort and this is someone that needs to be with your provider for months , you know , because you need to have that conversation . But I'm you know I'm not advocating for or against , I just want people to understand why you're doing this . Most of the time .
I would say I would advocate for more of a continuous glucose monitor for a patient , so then they can be aware of what the foods are spiking their glucose and how they can change it .
And then also working on their overall behavior and learning what it is to eat healthy , learning what their food reacts to and what their body reacts to , and exercise and lifestyle management . This can be due in conjunction with that , but there are so many additional side effects that if a person is not aware of it , it may not be helpful .
This is my info for the day . I hope it helps and you know that's just kind of my thinking upon different metabolic health things . But as a provider and also as a overall health coach , I really feel that people need to understand what they're putting into their body in all aspects .
People are so quick to put the food in , but they're not willing to do the work to stop what's going on in the overall mechanism of action , and I hope this helps a little and you guys have a good rest of your day .