Medizin - Open Access LMU - Teil 06/22

Deficient phagocytosis secondary to proteolytic breakdown of opsonins in peritonitis exudate

Fibrinolysis caused by cardio-pulmonary bypass and shed mediastinal blood retransfusion

Trauma und Entzündung

Auswirkungen chirurgischer Infektionen auf die Stimulierbarkeit zur Chemilumineszenz von Granulozyten und die Freisetzung granulozytärer Elastase

Rapid detection of human chromosome 21 aberrations by in situ hybridization

Plasmid clones containing up to 94 kilobases of single-copy DNA from band q22.3 of chromosome 21 and a complete pool of insert DNA from a chromosome 21 recombinant library have been used to rapidly detect numerical and structural aberrations of chromosome 21 by in situ hybridization in both metaphase and interphase cells. A trisomic karyotype, diagnostic of Down syndrome, is readily detected in nonmitotic cells because the majority of their nuclei exhibit three discrete foci of hybridization, in...

Centennial of Wilhelm Waldeyer´s introduction of the term "chromosome" in 1888

Detection of chromosome aberrations in metaphase and interphase tumor cells by in situ hybridization using chromosome-specific library probes

Chromosome aberrations in two glioma cell lines were analyzed using biotinylated DNA library probes that specifically decorate chromosomes 1, 4, 7, 18 and 22 from pter to qter. Numerical changes, deletions and rearrangements of these chromosomes were radily visualized in metaphase spreads, as well as in early prophase and interphase nuclei. Complete chromosomes, deleted chromosomes and segments of translocated chromosomes were rapidly delineated in very complex karyotypes. Simultaneous hybridiza...

Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization using recombinant DNA libraries

A method of in situ hybridization for visualizing individual human chromosomes from pter to qter, both in metaphase spreads and interphase nuclei, is reported. DNA inserts from a single chromosomal library are labeled with biotin and partially preannealed with a titrated amount of total human genomic DNA prior to hybridization with cellular or chromosomal preparations. The cross-hybridization of repetitive sequences to nontargeted chromosomes can be markedly suppressed under appropriate preannea...

Sorting of chromosomes by magnetic separation

Chromosomes were isolated from Chinese hamster x human hybrid cell lines containing four and nine human chromosomes. Human genomic DNA was biotinylated by nick translation and used to label the human chromosomes by in situ hybridization in suspension. Streptavidin was covalently coupled to the surface of magnetic beads and these were incubated with the hybridized chromosomes. The human chromosomes were bound to the magnetic beads through the strong biotin-streptavidin complex and then rapidly se...

Rapid interphase and metaphase assessment of specific chromosomal changes in neuroectodermal tumor cells by in situ hybridization with chemically modified DNA probes

Repeated DNAs from the constitutive heterochromatin of human chromosomes 1 and 18 were used as probes in nonradioactive in situ hybridization experiments to define specific numerical and structural chromosome aberrations in three human glioma cell lines and one neuroblastoma cell line. The number of spots detected in interphase nuclei of these tumor cell lines and in normal diploid nuclei correlated well with metaphase counts of chromosomes specifically labeled by in situ hybridization. Rapid an...

Functional evaluation of penile hemodynamics

Pharmakologie von Herz und Kreislauf

Jodsalzprophylaxe in europäischen Ländern

Zur Neubewertung der Daten aus Hiroshima und Nagasaki

Krebsmortalität in Hiroshima und Nagasaki - Neue Risikoschätzungen und ihre Bewertung

Cancer mortality in Hiroshima and Nagasaki

Neoplastic transformation of mouse C3H 10T1/2 and syrian hymster embryo cells by different types of ionizing radiation

Response of different ames tester strains to ionizing radiation

Response of the Ames Test to different Types of ionizing Radiation

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Significance of autoimune reactions to pancreatic juice in Crohn`s disease

Zur Lage unserer Universität

Isoproterenol decreases activation by insulin of insulin receptor kinase in intact rat adipocytes

Non-toxic goiter

Suppressor cell function in thyroid autoimmune disease is affected by plasmid encoded proteins of enteropathogenic Yersinia

Nerve growth factor

Molekulare Analyse der beta-Tubulingene aus dem Makronukleus des hypotrichen Ciliaten "Stylonychia lemnae"

Isoproterenol modulates insulin activation of insulin receptor kinase in intact rat adipocytes

Autoimmunität bei chronisch-entzündlichen Darmerkrankungen

Hemodynamic and renal effects of atrial natriurectic peptide in normal men

Hemodynamic and renal effects of atrial natriuretic peptide (a-hANP) in normal man.