Medizin - Open Access LMU - Teil 05/22 - podcast cover

Medizin - Open Access LMU - Teil 05/22

Ludwig-Maximilians-Universität München•epub.ub.uni-muenchen.de
Education
Die Universitätsbibliothek (UB) verfügt über ein umfangreiches Archiv an elektronischen Medien, das von Volltextsammlungen über Zeitungsarchive, Wörterbücher und Enzyklopädien bis hin zu ausführlichen Bibliographien und mehr als 1000 Datenbanken reicht. Auf iTunes U stellt die UB unter anderem eine Auswahl an elektronischen Publikationen der Wissenschaftlerinnen und Wissenschaftler an der LMU bereit. (Dies ist der 5. von 22 Teilen der Sammlung 'Medizin - Open Access LMU'.)
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Episodes

Transport of F1-ATPase subunit β into mitochondria depends on both a membrane potential and nucleoside triphosphates

Transport of cytoplasmically synthesized precursor proteins into or across the inner mitochondrial membrane requires a mitochondrial membrane potential. We have studied whether additional energy sources are also necessary for protein translocation. Reticulocyte lysate (containing radiolabelled precursor proteins) and mitochondria were depleted of ATP by pre-incubation with apyrase. A membrane potential was then established by the addition of substrates of the electron transport chain. Oligomycin...

Dec 15, 19860

Rationelle Diagnostik der erektilen Dysfunktion unter Anwendung eines pharmakologischen Tests

Bei 100 multidisziplinär untersuchten Patienten mit mindestens 1jähriger erektiler Dysfunktion (E. D.) wurde zu diagnostischen Zwecken ein pharmakologisches Testverfahren mit intrakavernöser Applikation eines Papaverin-Phetolamingemisches angewandt. Aufgrund dieses pharmakologischen Testes gelingt eine Einordnung in 1. nichtvaskulär bedingte E. D., 2. vaskuläre E. D. mit pathologischen inflow-Bedingungen und 3. vaskuläre E. D. mit pathologischen outflow-Bedingungen. Gruppe I (n = 13) erreichte m...

Jan 01, 19860

Induction of chromosome shattering by ultraviolet light and caffeine: The influence of different distributions of photolesions

Cells of synchonized and of asynchronously growing cultures of a V79 Chinese hamster line were microirradiated with a low poweer laser-UV-microbeam of wavelength 257 nm. Ultraviolet light was either focused onto a small part of the nucleus (mode I) or distributed over the whole nucleus (mode II). Following microirradiation, the cells were incubated for 7–20 h with caffeine (1–2 mM) until chromosome preparation was performed. After both modes of microirradation, shattering of the entire chromosom...

Jan 01, 19860

Detection of chromosome aberrations in the human interphase nucleus by visualization of specific target DNAs with radioactive and non-radioactive in situ hybridization techniques: diagnosis of trisomy 18 with probe L1.84

The localization of chromosome 18 in human interphase nuclei is demonstrated by use of radioactive and nonradioactive in situ hybridization techniques with a DNA clone designated L1.84. This clone represents a distinct subpopulation of the repetitive human alphoid DNA family, located in the centric region of chromosome 18. Under stringent hybridization conditions hybridization of L1.84 is restricted to chromosome 18 and reflects the number of these chromosomes present in the nuclei, namely, two ...

Jan 01, 19860
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