Medizin - Open Access LMU - Teil 03/22

Biogenesis of Glyoxysomes

Biosynthesis of isocitrate lyase, a tetrameric enzyme of the glyoxysomal matrix, was studied in Neurospora crassa, in which the formation of glyoxysomes was induced by a substitution of sucrose medium by acetate medium. * 1. Translation of Neurospora mRNA in reticulocyte lysates yields a product which has the same apparent molecular weight as the subunit of the functional enzyme. Using N-formyl[35S]methionyl tRNAMetf as a label, the translation product shows the same apparent size which indicate...

Biochemical, Pharmacological, and Functional Aspects of Glandular Kallikreins

Biochemistry and functional aspects of human glandular kallikreins

Human urinary kallikrein was purified by gel filtration on Sephacryl S-200 and affinity chromatography on aprotinin-Sepharose, followed by ion exchange chromatography on DEAE-Sepharose. In dodecylsulfate gel electrophoresis two protein bands with molecular weights of 41,000 and 34,000 were separated. The amino acid composition and the carbohydrate content of the kallikrein preparation were determined; isoleucine was identified as the only aminoterminal amino acid. The bimolecular velocity consta...

Urinary Kallikrein in normotensive Subjects and in Patients with Essential Hypertension

Induction of chromosome shattering and micronuclei by ultraviolet light and caffeine

August Weimann´s contribution to cytogerontology

Detection of laser-UV microirradiation-induced DNA photolesions by immunofluorescent staining

A low-power laser-UV microbeam of wave-length 257 nm was used for microirradiation of a small part of the nucleus of Chinese hamster cells. Following fixation in interphase or in the subsequent metaphase indirect immunofluorescent staining was performed with antiserum to photoproducts of DNA treated with far UV light. The results show that antibodies specific for UV-irradiated DNA can be used for a direct detection of laser-UV microirradiation-induced DNA photolesions. The potential usefulness o...

Pheochromocytoma and multiple endocrine adenomatosis

Interaction of TSH and "TSI" with thyroid membranes

Proteinase inhibitors in severe inflammatory processes (septic shock and experimental endotoxaemia)

Clotting and other plasma factors in septicemia

Der Patient Schw. J. - Beobachtungen von 1963 bis 1979 und Folgerungen für die Endokrinologie

ACTH-producing pituitary adenomas in Cushing´s disease

Biophysical studies with spatially correlated ions

Proximity functions for electrons up to 10 keV

Nonparametric representation of dose-effect relations

The correction for the gamma-ray component in neutron therapy

Neutron beams for therapy always contain some gamma ray contamination that varies with depth and with distance from the beam axis. The problem therefore arises how the varying gamma ray contribution should be accounted for in dose specification. Not infrequently a ``total effective dose'' DE is quoted that is equal to the neutron dose plus the gamma ray dose divided by a constant weight factor tau. On general biophysical considerations this appears to be not a valid approach since it must be ass...

Aktuelle Probleme der Strahlenkarzinogenese

Theoretische Aspekte der Strahlenbiophysik

Zelltransformationen und Risiken kleiner Strahlendosen

Induction of mammary neoplasms in the SPrague-Dawley rat by 430 keV neutrons and X-rays

Eine seltene Kombination organspezifischer Autoimmunkrankheiten

Hypothalamisch-hypophysäres Cushing-Syndrom

Strumaprophylaxe

Hyperthyreose

The validity of serum TSH measurements by immunoassay

Alimentärer Jodmangel im Hochland von Tanzania

Zirkulierende und Urin-Katecholamine bei Phäochromozytom

Klinische Bedeutung der ACTH-Bestimmung

Paraneoplastische ACTH-Produktion bei Carcinom-Patienten