Medizin - Open Access LMU - Teil 03/22

Eine anatomische Untersuchung des Infiltrationsortes bei zwei verschiedenen Injektionsmethoden

Praziquantel bei Parasitosen

Recognition and specifity in the intracellular transfer of mitochondrial proteins

Biogenesis of mitochondrial membrane proteins

Purification and Characterisation of a Pore Protein of the Outer Mitochondrial Membrane from Neurospora crassa

The major protein of the outer mitochondrial membrane of Neurospora was purified. On dodecylsulfate-containing gels it displayed a single bend with an apparent molecular weight of 31000. reconstitution experiments with artifical lipid bilayers showed that this protein forms pores. Pore conductance was dependent on the voltage across the membrane. The protein inserted into the membrane in an oriented fashion, the membrane current being dependent on the sign of the voltage. Single pore conductance...

Knochenmineraldichte nach Nierentransplantation

Vitamin status in patients on chronic anticonvulsant therapy

Eosinophile Polyneuropathie und allergische Angiitis.

Impaired biotin status in anticonvulsant therapy

In 264 epileptics undergoing long-term therapy with anticonvulsants, significantly reduced plasma biotin levels were found compared with a normal control group: 74% of the epileptics had biotin levels for those treated with sodium valproate were higher than for those treated with phenytion, primidone, or carbamazepine. The observed reduction in biotin levels might be a factor influencing the efficacy of these three antionvulsants.

Elektromyographische Zeichen einer neurogenen Beteiligung bei hypokaliämischer Lähmung infolge Diuretika-Abusus

Porphyria cutanea tarda, Polyneuropathie und Myopathie bei kleinzelligem Bronchialkarzinom

Untersuchungen zum Verhalten von resorbierbarem und nicht-resorbierbarem Nahtmaterial bei der Lymphgefäßnaht

Ca2+ uptake to purified secretory vesicles from bovine neurohypophyses

Purified secretory vesicles isolated from bovine neurohypophyses were found to take up Ca2+ when incubated at 30°C in media containing 10−7 to 10−4 M free Ca2+. At 10−4 free Ca2+ 19 nmol/mg protein were taken up within 30 min. The initial uptake at this Ca2+ concentration was about 2 nmol/mg protein per min. The uptake of Ca2+ to secretory vesicles was not affected by ATP, oligomycin, ruthenium red, trifluoperazine, Mg2+ or K+, but was inhibited by Na+ and Sr2+. From these characteristics it can...

Uptake of Ca2+ by isolated secretory vesicles from adrenal medulla

Intact secretory vesicles isolated from bovine adrenal medulla contain 94 nmol Na+ per mg of protein, and Ca2+ influx into the vesicles is inhibited by increasing concentrations of extravesicular Na+ (but not of K+, Li+ or choline+) or by addition of the Na+ ionophore monensin. Thus Ca2+ influx is determined by the Na+ gradient across the vesicular membrane. Half maximal inhibition of Ca2+ influx occurs with 34 mM Na+ extravesicularly. The fact that Ca2+ can also be released from the vesicles by...

Liquorproteine bei der Neuromyelitis optica

Es werden zwei Fälle von Neuromyelitis optica beschrieben, die jeweils eine hochgradige Erhöhung der Proteine im Liquor aufwiesen. Während ein Patient nach 6monatigem Krankheitsverlauf starb und pathologisch-anatomisch untersucht werden konnte, überlebte der andere Patient mit erheblichen Residuen. Dieser Fall zeichnete sich dadurch aus, daß deutlich erhöhte IgA- und IgM-Werte sowohl im Liquor als auch im Serum vorlagen. Es wird diskutiert, ob die gefundenen Liquorveränderungen möglicherweise ei...

Lipomatosis symmetrica benigna und neurologische Komplikationen bei chronischem Alkoholismus

Erniedrigung des Biotins als möglicher Faktor im Wirkmechanismus von Antiepileptika

Involvement of Mhc Loci in immune responses that are not Ir-gene-controlled

Twenty-nine randomly chosen, soluble antigens, many of them highly complex, were used to immunize mice of two strains, C3H and B10.RIII. Lymphnode cells from the immunized mice were restimulated in vitro with the priming antigens and the proliferative response of the cells was determined. Both strains were responders to 28 of 29 antigens. Eight antigens were then used to immunize 11 congenic strains carrying different H-2 haplotypes, and the T-cell proliferative responses of these strains were d...

Tauchunfälle - Ursachen und rechtsmedizinische Aspekte

Forensisch-pathologische Aspekte des Hirntraumas

Identifizierung bei Massenkatastrophen

Analyse tödlich verlaufender Ski-Unfälle

T cell-specific suppressor factor(s) with regulatory influence on interleukin 2 production and function

In this study we report that alloantigen-activated spleen cells produce both amplifying and suppressive factors under the same conditions. Both types of soluble mediators--as detected in different assay systems-- were present in the supernatants of in vivo sensitized and in vitro restimulated spleen cell populations and were separable by gel filtration. As shown by others, the amplifying factor (IL 2) was eluted in the size range of 30,000 m.w. The suppressive factor(s) (SF) was eluted in the si...

Frequency analysis of cytolytic T cell precursors (CTL-P) generated in vivo during lethal rabies infection of mice. I. Distinction of CTL-P with different interleukin 2 sensitivity

The aim of this study was to determine the number and state of activity of cytolytic T lymphocytes (CTL) and their precursors (CTL-P) present in vivo during the early stages of viral infection. The local response to lethal infection with rabies virus was used as a model system that is not accessible to analysis by secondary activation in vitro. The local response to alloantigen served as a control. Experimental protocols were established that allow frequency estimates of in vivo antigen-triggere...

Stimulation von TSH durch TRH - ein Vergleich von intravenöser, oraler und intranasaler Applikation

Wertigkeit der direkten Bestimmung des freien Thyroxins im Vergleich zum freien Thyroxin-Index und dem Thyroxin-TBG-Quotienten in der Schilddrüsenfunktionsdiagnostik

Combined HMG/HCG treatment in subfertile men with idiopathic normogonadotropic ogliozoospermia

Urinary cholesterol in cancer screening

Cholesterol determinations in morning urine samples were taken in 235 selected patients with a positive test for microscopic hematuria. Values ranged from 0.2 to 76.0 mg (median 5.5) in 23 patients with urologic malignancies and from 0.1 to 33.4 mg (median 1.1) in 38 patients with various benign diseases of the kidney or urogenital tract. In the 28 patients with urinary tract infections and 146 subjects without evidence of disorders of the kidney and the urogenital system, urinary cholesterol ex...

Results of oral TRH test in the differentiation of compensated and decompensated autonomous thyroid nodules

Plötzlicher, unerwarteter Tod bei seltenen cervicooccipitalen Anomalien und inadäquatem Trauma