Matters Microbial #64: Making Sense of the Microbiome

Today, Dr. Patrick Schloss, Professor in the Department of Microbiology and Immunology in the School of Medicine at the University of Michigan, joins the #QualityQuorum to discuss how the human microbiome is studied, possible pitfalls in such data analysis, and what tools he and his coworkers have developed to lead toward repeatable, hypothesis-driven science.

Host: Mark O. Martin

Guest: Patrick Schloss

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• An overview of how the gut microbiome is analyzed.
• One of the articles discussed by Dr. Schloss exploring reproducibility in microbiome studies: “Identifying and Overcoming Threats to Reproducibility, Replicability, Robustness, and Generalizability in Microbiome Research.”
• Another article discussed by Dr. Schloss, regarding the link between the microbiome and obesity:  “Looking for a Signal in the Noise:  Revisiting Obesity and the Microbiome.”
• An article from Dr. Schloss’ research team that explores a link between the human microbiome and a type of colorectal cancer.
• A link to the MOTHUR project, used to analyze microbiome data.
• A link to a video by Dr. Schloss:  “Understanding Disease Through the Lens of the Microbiome.”
• Dr. Schloss’ YouTube channel about data analysis.
• Dr. Schloss’ research group website.
• Dr. Schloss’ faculty website.

Intro music is by Reber Clark

Send your questions and comments to mattersmicrobial@gmail.com