What does real-world data tell us about frontline treatment strategies for MCL?

During the 2021 ASCO Annual Meeting, the Lymphoma Hub spoke with Michael Wang, MD Anderson Cancer Center, Houston, US, and Peter Martin, Weill Cornell Medicine, New York, US. We asked, What does real-world data tell us about frontline treatment strategies for mantle cell lymphoma (MCL)? 

To answer this question, Martin firstly evaluates data from a retrospective study, which included adult patients with MCL in the nationwide Flatiron Health EHR-derived deidentified database. He describes the results in 3,455 previously untreated patients, including treatment patterns in real-world clinical practice and how they compare with clinical studies, patient outcomes, and the role of stem cell transplantation. Wang then shares his opinion on these data, focusing on the time gap between frontline clinical data and changes to practice patterns. He also outlines further data on promising novel regimens for patients with MCL.

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