How do you choose among different BTK inhibitors for treating CLL? - podcast episode cover

How do you choose among different BTK inhibitors for treating CLL?

Dec 02, 20227 min
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Episode description

The Lymphoma Hub was pleased to speak with Francesc Bosch, Vall d’Hebron Barcelona Hospital Campus, Barcelona, ES. We asked, How do you choose among different BTK inhibitors for treating CLL?


Bosch opens by outlining common BTK inhibitors such as ibrutinib, acalabrutinib, and zanubrutinib, noting that comparable efficacy and activity rates can cause difficulty when determining the most appropriate treatment; however, safety profiles vary. Bosch goes on to suggest that other factors, such as patient comorbidities, may be more useful; for example, the varying cardiovascular toxicity of BTK inhibitors may be pertinent when treating patients with comorbid cardiovascular conditions.

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