Advanced biomarker testing and a personalized 100-day intervention to adjust biological age are at the heart of a new longevity venture called Hundred. The AI-driven platform uses data from wearable technology together with users’ medical histories to devise individual health plans. Billed as a ‘doctor in your pocket,’ the goal is to extend quality of life to a vibrant 100 years, through tailored insights and guidance. Hundred’s founder, Tyler Smith, is spearheading an effort to redefine how we ...
Jul 21, 2025•39 min•Ep. 279
While most people regularly check their blood pressure or glucose, few consider routinely assessing their body's ability to move—and yet, this may be just as crucial to long-term health. Andrew Menter, CEO of Physmodo, joined Peter Bowes to explore the software company’s mission to raise the profile of movement as a vital sign of good health. Andrew shares his personal journey from a career in law and finance to entrepreneurship in movement science, motivated in part by his athletic pursuits and...
Jul 14, 2025•27 min•Ep. 278
James Schmachtenberger has had quite a life, and we suspect he is only just getting started. The co-founder of Qualia Life joined us for a wide-ranging conversation about cognitive enhancement, sleep, doomscrolling, zombie cells, joint health and much more. We discuss the interconnections of mind and body, the magic of magnesium, the frontier of senolytics, and how three days in a Mexican clinic led him on an inspiring journey into the world of longevity research. We delve into the science behin...
Jun 05, 2025•42 min•Ep. 277
In this episode we explore the concept of a longevity mindset. Nick Engerer is on a mission to redefine human longevity not as a distant goal but as a present-day mindset—an approach that requires a shift in thinking. To help us in this quest, Nick has developed a new digital platform, A Longer Life, which includes a free Longevity Mindset course. In this interview he shares his vision for a future where health optimization is available to everyone. We delve into the nuances of living not just l...
May 25, 2025•51 min•Ep. 276
Think of aging as syndrome that can be overcome to live the best life possible. Dr. Michael Aziz, author of The Ageless Revolution , takes this approach to promote longevity and overall well-being, based on the principles of functional medicine. In our conversation, he emphasizes the need for a holistic - whole body - approach to health, and advocates for practical lifestyle changes, including dietary adjustments and intermittent fasting, to promote longevity and overall well-being. The New York...
May 11, 2025•38 min•Ep. 275
In this episode we explore how the skills needed to live a longer healthier life can be honed through our own failures. Prof. Manu Kapur discusses the concept of 'productive failure' and how learning from our mistakes can lead to deeper understanding and personal growth. He shares his journey from aspiring soccer player to a researcher in learning sciences, discovering the importance of failure as a mechanism for learning. The conversation explores how these principles can be applied to health, ...
Apr 16, 2025•30 min•Ep. 274
How can a joyful and holistic approach to food help us to live longer and better? Elizabeth Borelli is a lifestyle coach, nutrition expert and author of Tastes Like La Dolce Vita, where she shares her mission to help us live not only longer but better—enjoying a long healthspan, a life where we stay healthy, active, and mentally sharp well into our later years. Her work weaves together a passion for nutritious, satisfying food and practical wellness strategies inspired by Italy’s famously health...
Mar 21, 2025•36 min•Ep. 273
Stem cell therapy is a growing field of medical intervention that is being used to enhance longevity and healthspan. Advancements in research, biotechnology, and regenerative medicine have expanded its potential applications but it also raises both ethical and efficacy concerns. The primary ethical issue comes from the use of human embryos, which some people believe is morally problematic. While many countries regulate or restrict their use, others allow research with oversight. In this intervie...
Mar 14, 2025•44 min•Ep. 272
Does longevity science have a branding problem? Dr. Darshan Shah believe it does. In this interview the founder and CEO of Next Health discusses the evolving landscape of health optimization, emphasizing the importance of healthspan over mere lifespan. He shares his personal journey from a traditional medical practice to a focus on functional medicine, highlighting the significance of diet, lifestyle changes, and innovative treatments in enhancing health. Dr Shah also explains the role of Next H...
Feb 19, 2025•36 min•Ep. 271
Dr. Stephanie Estima is on a mission to empower women by unlocking the potential of their biology. For too long seen as “smaller archetypes of men” she says there is now a growing understanding of the “cadences of women” and their distinct health journeys. In this interview we explore the significance of tracking cycles, understanding the different stages in life, including menstrual and perimenopausal phases, the impact of dietary choices, the profound effects of resistance training and importa...
Feb 09, 2025•54 min•Ep. 270
Cynthia Thurlow is a nurse practitioner, author and podcast host. She advocates for a balanced approach to healthcare that marries conventional and functional medicine. With experience in clinical medicine spanning two decades, Thurlow specializes in helping women overcome hurdles such as weight gain, low energy, and food cravings, as well as navigating perimenopause and menopause. In this interview with Peter Bowes she explains the importance of a back-to-basics approach, highlighting stress ma...
Jan 27, 2025•45 min•Ep. 269
Dr. Terry Wahls is a courageous advocate for health transformation. Her journey is not just a personal battle against multiple sclerosis; it's a testament to the resilience of the human spirit. With a unique approach that intertwines nutrition, movement, and a positive mindset, Wahls has developed a protocol for thriving, against the odds. Suffering the debilitating effects of MS, with physical and mental decline, she decided to focus on the health of her mitochondria. Based on the principles of...
Jan 19, 2025•41 min•Ep. 268
Maintaining optimal hormone levels as we grow older plays a crucial role in supporting mitochondrial health. When they become imbalanced, it can lead to reduced energy, increased inflammation, and a heightened risk of age-related conditions. In this, the first a series of interviews with leading female health practitioners, we explore the critical role of mitochondria in cellular health and the significant impact of hormones - for both women and men - on longevity. Dr. Felice Gersh, the medical ...
Jan 08, 2025•48 min•Ep. 267
What if the best days of our lives were to come in our 70s or later? The societal norms around aging are far from optimistic, preferring to frame the process around dotage and frailty. But such views are increasingly being challenged, not least because the evidence suggests we can be active, purposeful and fulfilled, well beyond the traditional age of retirement. In her book, Turning: The Magic and Mystery of More Days, Becky Blue delves into the emotional, physical, and psychological aspects of...
Dec 23, 2024•38 min•Ep. 266
Longevity Fest in Las Vegas, one of the world's premier gatherings of health professionals, has just wrapped up for another year. The meeting of the American Academy of Anti-Aging Medicine (A4M ) attracts experts from around the world. Doctors, nurses, researchers and health entrepreneurs share insights into the latest biotech, supplementation and health protocols to promote a long healthspan - the number of years we live free of chronic disease. We met up with Jen Scheinman from Timeline to dis...
Dec 17, 2024•12 min•Ep. 265
Accurate body composition data is often seen as the holy grail of information for the longevity-minded biohacker. Calipers are an accurate way to measure body fat. Smart scales and medical facilities equipped with DEXA machines also do a good job. But now it is possible to generate body composition data using the camera on your phone. In this episode, Jason Moore, CEO and founder of Spren, discusses the intersection of technology and health and the significance of understanding body metrics like...
Nov 30, 2024•44 min•Ep. 264
As we get older, how can we still enjoy a runners high or exercise-induced euphoria, while being careful not to get injured? Dr. Kevin R. Stone is an orthopedic surgeon, the founder of the Stone Clinic in San Francisco, and author of Play Forever: How to Recover from Injury and Thrive. With a passion for helping patients play until they drop, Dr. Stone is redefining what it means to maintain a high-quality, active lifestyle across the decades. In this conversation he challenges the conventional ...
Nov 11, 2024•34 min•Ep. 263
Loneliness, which affects how long people live, is at epidemic levels. Social isolation is not confined to the elderly, although the anxiety caused by feeling alone is borne especially hard by older people. Could artificial intelligence help? Dor Skuler, co-founder of Intuition Robotics, joined us to explain that AI-driven technology could be part of the solution. The company has developed ElliQ, an AI companion that keeps people company at home through conversations and activities that connect ...
Oct 20, 2024•40 min•Ep. 262
The traditional idea of retirement is changing with people now looking for new ways to continue contributing and finding purpose in their lives. Campbell Gerrish and Caroline Brecker, co-founders of Third Half Advisors, have developed the concept of the 'third half' and how to navigate the bonus years of life. They stress the need to envision a different kind of future and ways to explore fresh opportunities post-retirement. In this interview Campbell and Caroline discuss the importance of build...
Oct 03, 2024•33 min•Ep. 261
Sky Bergman's film, Lives Well Lived, explored the joys of growing old, the value of wisdom, and the appreciation of life. Through interviews with people aged 75 and older, the documentary highlighted the resilience, sense of joy and positivity that come with age. The film has now evolved into a book, Lives Well Lived Generations , where Sky shares her personal journey of embracing aging, cherishing every wrinkle and gray hair, and fostering connections across generations. She explores the signi...
Sep 25, 2024•35 min•Ep. 260
VILPA (Vigorous Intermittent Lifestyle Physical Activity) is a type of physical activity that involves short bouts of strenuous activity. It is opportunistic and integrated into daily life. It can be as simple as taking the stairs instead of the elevator, doing squats, or parking farther away to walk more. This type of activity improves fitness and provides health benefits, including cardiovascular health, weight control, muscle strength, bone health, and mental well-being. In this episode, Mari...
Sep 16, 2024•38 min•Ep. 259
Vegetable oils are sometimes referred to as seed oils because they come from the seeds of plants. The most commonly used include corn, soybean, canola, palm, peanut, safflower, and sunflower oil. They are widely touted as an alternative to butter, but Dr. Cate Shanahan, a physician-scientist, challenges the notion that these oils are a heart-healthy, pro-aging option. Navigating the dietary landscape can be a daunting task, with mixed messages creating widespread confusion. The inclusion of vege...
Aug 29, 2024•43 min•Ep. 258
The power of innovative storytelling to better understand human longevity has been harnessed by a unique community known as JellyfishDAO. The group - made up of filmmakers, life extension professionals, and blockchain experts - aims to accelerate the acceptance and understanding of aging science through compelling media projects. In this Live Long interview we unpack how JellyfishDAO is pioneering a future where stories and science work hand in hand to extend human healthspan and longevity. Dani...
Aug 07, 2024•42 min•Ep. 257
Do we all have equal access to the benefits of longevity science? Undoubtedly not, although many of the proven interventions are more accessible than some people realize. "The metabolic benefits of appropriate nutrition, appropriate sleep, appropriate exercise, and also stress and a sense of purpose can outweigh even the very expensive interventions," says Dr. Robert Lufkin, one of the longevity experts featured in Reversed: The Race for Longevity, which dives into the science and personal stori...
Jul 26, 2024•36 min•Ep. 256
DIY blood testing is growing in popularity. At-home testing kits make it easy to collect our own samples and receive lab results online. But could we be over-testing – just because we can? Michael Dubrovsky is the co-founder of SiPhox Health, a home blood testing system that claims its results are as accurate as traditional methods. What is SiPhox Health? It is a home blood testing that can measure 17 biomarkers with just a few drops of blood. This system allows people to mail their blood sample...
Jul 19, 2024•45 min•Ep. 255
Retail wellness companies are becoming a more familiar sight on the high street, whether it’s for an infrared sauna, red light therapy, hyperbaric oxygen, cryotherapy or intravenous drip, there’s a lot of choice. It feels good at the time. You might leave with a healthy glow, but how many of these practices actually change our health outcomes? Indeed, are they designed to do that? Are they really good for us? “We want people to do more of what they love because I assure you, the more you do the ...
Jun 24, 2024•47 min•Ep. 254
Much of the buzz around full body MRI scans has resulted from attention given to them by influencers and celebrities who have posted about their experiences. At a cost of up to $2,500 the scans are touted as a way to catch medical problems, such as cancer, at a stage when they can be treated. But they have been widely criticized by professional medical bodies and are generally not covered by health insurance. This video is a response by the president of the American College of Preventive Medicin...
Jun 12, 2024•50 min•Ep. 253
There has been a surge in interest in the use of full body MRI (magnetic resonance imaging) scans as a screening tool to spot early signs of disease. Influencers and celebrities have posted about their experiences, creating an additional buzz around these screening interventions. At a cost of up to $2,500 the scans are touted as a tool to catch medical problems, such as cancer, at a stage when they can be treated. Unlike X-ray and CT scans, MRI does not involve exposure to radiation. To try to l...
Jun 12, 2024•56 min•Ep. 253
David Robson has always found forming new connections and meeting strangers challenging. As a science writer - and confronted by his own insecurities - he decided to delve into the research that suggests forging new relationships has a direct impact on healthy aging. The result is Robson's latest book, The Laws of Connection: The Scientific Secrets of Building a Strong Social Network, which reveals how people impacted by serious illnesses fare much better when they have people around them. Robso...
Jun 03, 2024•49 min•Ep. 252
Memory loss is often cited as one of the most worrying aspects of growing older. But what if the section of the brain that's responsible for memory could be stimulated by simply sniffing a few pleasant odors? There is extensive research pointing to a relationship between exposure to different smells and memory improvement. A clinical trial led by Prof. Michael Leon at the Department of Neurobiology and Behavior, University of California, Irvine, suggests the loss of olfaction can cause the memor...
May 17, 2024•32 min•Ep. 251
