Copy of Podcast - Episode 3
[00:00:00] I wish I could, you know, scream from rooftops all over the place because man. Like somebody's nagging knee is nowhere near as severe as the low back, but we can fix all of it, right? We, we can get people better and it's just, it's just incredible.
[00:01:00] Hi everybody. I am so excited. So over the moon to have Dr. Sabrina Solt here with us today. And she is a wealth of information on a lot of regenerative medicine topics. Many, many more, uh, than I think, uh, people realize are available or their applications. And so, um, I remember hearing her just passively speak about these concepts and topics at a recent conference, and I was just.
Dumbfounded and I figured I need to get her on the podcast because there's just gonna be so much, uh, to, uh, pick her brain on. So, um, I am so excited to have you here and, uh, how are you doing today?
Oh, thank you so much for having me. I was so excited to come on. I just obviously adore you as you know. Um, so I was happy to just, you know, pour into your community and hopefully teach them something that [00:02:00] might not even be on their radar, you know?
Right, right, right. And that's the thing is you don't hear a lot of folks talk about, um. Regenerative medicine or some of the tools we'll get into in the mold community, or if they do, it's more affiliated with the Lyme co-infections and like the joint repair after chronic Lyme damage. So I'm super stoked to have you here, to get into it.
So, uh, without, you know, further ado, can you tell me a little bit about how you got into regenerative medicine and, you know, what do you really love about it? What really spurs you on there?
I guess I'll answer that part first. What I love about it the most is that. It works in the simplest way, it is the best way I've seen clinically to actually get people out of pain and heal and repair the body using the most natural thing possible. So it's pretty amazing.
Um, I got into it. I have a history of Being athletic. I played soccer, played volleyball, did fitness competitions. and back when I was doing [00:03:00] rotations, I had the pleasure of being on a rotation with a doctor who was doing prolotherapy, which was one of the, most basic forms of regenerative injection.
you do a specific needling technique and deliver a solution that's both nutritive and. Irritating to the area over the course of several treatments, it allows the body to be reminded that there's an injury there and to bring more resources and start to reheal it. I got to treat a guy's shoulder and over the course of several sessions, we saved him from having surgery.
We got him off of pain medications and pretty much had his shoulder back to normal. after that. I was sold on it. that was, I like to call my gateway drug into the regenerative medicine field. after that, I dedicated myself to learning everything I could. So I started learning about PRP, which is, harvesting all of the growth factors present in a person's blood and utilizing those to heal an area.
After PRPI started getting into stem cells. Um, I utilized. Bone marrow stem cells from fat even started getting into things that you, uh, develop from birth tissue. So things like umbilical core products, amniotic products, [00:04:00] exosomes. There's a ton of different options out there, and they are all really cool to work with.
Awesome. So maybe we'll start off for people here, um, I would love to eventually get into exosomes if we can fit it in somewhere, but can you tell people what stem cells are? Like, what, what do they do? What's the deal with them?
So stem cells are basically immature, primitive cells that have not yet differentiated into, um, an end cell or an end tissue. The reason these are really cool is because when we. Can use them clinically or place them in the body, they have the ability to heal something that's been damaged. So let's just take an example of a knee with arthritis, right?
There's a ton of people that deal with knee issues. Normally when we start getting arthritis, it's actually a wearing down of the meniscus, which is that cartilaginous layer in that knee joint. People usually get that, uh, grinding sensation. Maybe some achiness starts to get worse with weather changes like overcast weather, and usually there's no.[00:05:00]
Treatment for it. People might get the rooster cone or hyaluronic acid injections, maybe a cortisone to take away the pain, and it's just kind of like here, placate this for many years until eventually you qualify for a knee replacement surgery, which may or may not get you outta pain or get you the results that you want.
When we use something like a stem cell therapy or a PRP or something else in our regenerative medicine toolbox, we can actually trigger that cartilage to heal and repair so that you can reverse. The arthritis, and that's the power within stem cells, right? They can create that new tissue. A lot of people are familiar with stem cells when it comes to the oncology or cancer field.
People hear a lot about bone marrow replacement or bone marrow transplants, especially in patients who have things like leukemia. And that's because we can actually get those new stem cells working to create A new blood cell lineage in the body to replace those cancerous cells that are affected by the leukemia.
Um, so this stuff isn't new, right? People have been using it for decades. It's just within the last decade or so that [00:06:00] it's really become common practice. not even common practice, but more accepted in the clinical sphere.
Mm-hmm. Um, and then just like out of curiosity on that, so we're talking about, repairing cartilage and kind of, growing and, filling in those gaps from that where, but what about the tear? Do you find that with these injection therapies of stem cells, that you will get fusion of tears and labrum and whatnot?
A hundred percent. We've seen, uh, tears repair and things like the rotator cuff in labrums, like you mentioned, both the glenohumeral or the glen labrum at the shoulder, the hip labrum. It can take time. Of course, these things aren't instant and I do like to make sure that we have that caveat, right?
Like it's not like a drug where you take the pill and then, you know, a couple hours later you feel fine. We're actually causing the tissue to repair and regenerate. So we're talking at least a good couple months of a repair cycle. But we do see the tears and we have had patients that have had pre and post MRIs to actually show that.[00:07:00]
Oh wow. And so when you say, um. Let's say someone undergoes, uh, treatment for a tear.
Do you find that they need multiple treatments or what, what does that end up looking like?
It depends. our approach is we always only ever start with one because we need to see how you do. In some instances, we have patients that get upwards of 80, 90, sometimes even a hundred percent improvement after that single session, in which case we're totally happy to say goodbye, you know, come back and see us if something else happens.
But. Great. We're so happy for you. Um, in general, I don't usually see less than like a 30% improvement, right? Because it's never black or white. It's never like, did they work or did they not work? It's how much improvement did we get you over what period of time? And generally speaking, if somebody does get improvement, we know that okay, you improve, you responded really well.
Doing a second treatment is only going to get you more results because now we're actually starting at a new baseline. You've actually [00:08:00] got new tissue. You've reached a different level, so we can go even further the next time.
Hmm. Okay. Dang, this is really wonderful. Um, so let's say, uh, someone is like, you know, I really wanna do a stem cell procedure. Um, what, what does that look like? So someone comes into the office, they're greeted by reception or you, and then what happens? What does that look like?
A lot of people do start with an online inquiry and they get to book a call with, um, our patient care coordinator and they kind of go over their options. We do have a really detailed stem cell guide that we send people in preparation for that call, and it has videos in there.
It even has our pricing structure. So we're super, super transparent with everything. Um, 'cause we want people to be prepared for this. You know, it's often a big investment of both, you know, resources, time. Finances, we try to be as transparent as possible, so usually on that call, the coordinator will go over your, your case and the degree of [00:09:00] injury that you have, how it happened, the areas that we need to treat, and from there.
She's been with me for like almost three years. She really does know, okay, this is likely what you're gonna need. Um, if she has any doubt that what she's suggesting is going to not, maybe not be right, she will convene with me and say, okay, hey, this is what this patient's got going on. This is what I think they need.
Let's double check. And the options can range from anything to just simple. PRP. Sometimes we get really mild situations and people benefit just from a PRP session. Uh, sometimes we have really, really severe cases and we have to do. A lot, and normally with those, when I say a lot, it's usually combination of different modalities.
So we might do stem cells from a patient's adipose tissue. We may also add in stem cells from the patient's bone marrow. We may add in the PRP, we may add in something like exosomes, and it can kind of span the gamut based on, again, what we're treating. Now, once we've decided that what our treatment plan's going to be.
At that point, the patient will then select, okay, this is when I want my [00:10:00] procedure date to be. And then about one to two weeks before the actual procedure date, uh, I get on a call with the patient and we dive into everything that they have going on in really great detail. My goal during that call is to be incredibly annoying and ask a bunch of questions about how the pain actually presents so that I can make sure that I'm formulating my treatment plan to hit everything that we need to hit to stop the pain.
And repair the area, right? Because I think this is a really important distinction to make. The area that's damaged is not always the thing that's generating the pain. So low backs, for example, um, people will say, Hey, I've got a disc issue in the low back and the low back's degenerating the type of pain that is being listed from the low back.
Often isn't from the disc degeneration itself or what we call a discogenic pain. It can actually sometimes be from compression at the facet joints or something aggravating one of the nerves. It's exiting the spine. And if I'm not doing my job to figure out, hey, what, what's the pain generator? Um, often the patients may not get the long-term results that they're [00:11:00] looking for.
So we do that consultation, and then of course, you come in for your procedure and we do quote per area, not per injection because. I'm not gonna split hairs on stuff like that, right? So if your low back requires 10 injections, it's just the low back, right? Um, if your shoulder requires four or five injections, it's just a shoulder.
We do full and complete treatments, and oftentimes even at the actual procedure, we add in additional modalities. At no additional cost to the patient. So we sometimes will add in red light therapy, shockwave therapy. Sometimes we'll even do scar therapy to help, um, reduce any adhesions that the scars might have.
Again, the whole goal being get you outta pain, get the areas repaired.
Right. Wow. Wow, wow, wow. Um, so if, let's say you're doing, uh, stem cell treatments in. In office. Um, what does harvesting and collecting stem cells look like
and are people like preparing in advance? I know this is a multi-part question, but perfect example is, you know, we know [00:12:00] that there are a lot of, uh, fat-soluble toxins that enter the body and land in the adipose tissue. Um, so, you know, I'm curious about what stem cell harvesting might look like and is there like a terrain cleanup that happens since we're, you know, self sampling for these things.
Yes, sort of. Um, when it comes to harvesting stem cells, the two places that we would harvest in a clinical setting would be either from the bone marrow or from the adipose tissue. Both of these procedures don't require any more than just a local anesthesia, so we know of the area that we're gonna be working on.
However, for some patients that are really nervous or that have a really high sensitivity to pain, we do have a mobile anesthesiologist that we work with who isn't. Fantastic. Uh, it's just a matter of coordinating with their schedule to get them to come in and they can put you under a very gentle twilight sedation for the whole entirety of the procedure.
And so some people do opt for that when it comes to preparing a person's terrain for stem cells, we actually do take [00:13:00] that very seriously. And I think this is one of the things that actually does set us apart in the stem cell world. I actually gave a lecture on this a couple years back at a stem cell conference,
a room of other stem cell physicians, about a hundred to 200 of them, and the feedback that I got was. A resounding positive because people wanted to know, Hey, how can I get better results for my patients? Because that happens to be the variable, right? The terrain is the variable.
You can have really, really wonderful seeds, but if the soil in the garden is not ready to receive them. You're not gonna grow anything. And this is kind of the way that I look at it. So with that, we have a basic guideline of qualifying factors, right? So we don't take any patients that have an active cancer, just 'cause we also don't know how stem cells are going to affect that possibly in a negative way.
We don't take any patients that are smokers. Smoking is one of the things that really damages stem cells, and that does actually translate additionally to nicotine use in general or chronic nicotine use. I should say, the occasional, you know, people use nicotine [00:14:00] recreationally these days for like a nootropic boost.
I'm not saying those populations. I think people who are constantly vaping, constantly chewing constantly. Smoking regular cigarettes, you are going to have a great deal of stem cell death and they're not gonna be able to proliferate and, impact the body the way that they should in a smoker.
additionally to that, There is a great deal of research around a person's adipose tissue and the state of the adipose tissue, and what the research has found is that the adipose tissue on somebody who has more adipose tissue or more on the heavier side, can be more inflammatory than the adipose tissue of a person who is leaner The only time that we will really say, okay, maybe you're not gonna be a great candidate if you are on more of the like obese or overweight category would be if we are solely treating a weight-bearing joint. And it mainly has to do with the impact of gravity on that area in that roughly every extra pound of fat could produce an extra nine pounds of pressure on that weightbearing [00:15:00] joint.
So we just wanna make sure that hey. We can work with the patient ahead of time to actually help them lose the weight and just prepare them a little better for that procedure, uh, versus kind of putting our name behind something and wondering, Hmm, this might not work. And we didn't do our best by you.
Mm-hmm. Um, and so, you know, we were chatting just before the podcast and probably should have hit record on that, but, so let's say, you know, there's so many people who are overweight in the US and I would say. Um, you know, with the endocrine disruptors that we battle back on a day-to-day basis and metabolic syndromes and all these things that play into it, what would you say that your favorite approach to navigating weight loss for people looks like?
I usually like to start with diet and lifestyle behaviors, and I should mention that when patients come on to work with us, we actually have an online learning platform that they get access to that really does walk them through how to prep your body for this, [00:16:00] how to really get the most
Out of this, and it was kind of born from this necessity where I wanted patients to have access to this knowledge so that they could really arm themselves as much as they felt comfortable with. But I didn't have the time in my schedule to spend with every patient. So at least this way, the videos, it's all standard.
Everybody gets the same information and they can kind of do with it what they wish. But the biggest things that I tell people to dial in at that point, for at least weight aspect, would be getting enough sleep. That's one of the biggest things is you have to be sleeping. If you wanna lose weight, if your body's in this stress state and can't repair and you're not getting enough rest, you're gonna hold onto weight.
And then the second thing is going to be changing up the diet. So we know processed foods are bad for us. We know alcohol's bad for us. We know a lot of excess sugars are not gonna be that great for us. So we really try to have patients focus in on what we'll call a regenerative diet. So making sure that you're getting plenty of protein.
And by plenty of protein, I mean at least. Three 30 gram meals a day because that amount of protein is what will [00:17:00] activate something called the leucine threshold, which will actually allow for muscle protein synthesis or healing and repair, right? So that becomes really important because now when we're getting in all this protein, we're actually providing the stem cells, the raw materials that they need to repair, because most of the things we're repairing are protein structures, right?
Cartilage is a protein structure. Tendons are protein structures. So we really need to give the raw materials to the body in that regard. By the time people usually make those basic changes, we usually see some degree of weight loss or at least a shift in body composition. If we need to go a little bit heavier than that, sometimes we will add in the GLP one class of peptides or medications.
People know these as, semaglutide, ozempic, wegovy, manjaro, and I feel like they've gotten a really bad reputation in the media at this Point. And in my experience, I've been prescribing these at very, very low doses, for the last three years or so. And normally what I found is people get [00:18:00] side effects and get the negative parts of them if they're dosed too high for too long without also including the other changes in the diet.
So. If these aren't a bandaid, they're not a magic fix. You can't just take these and not change everything else. We really gotta dial that in. And then, of course, looking at people's hormones. So hormonal disruption can be a really big part of why a person is holding onto excess weight. Uh, things like menopause, even pre menopause, perimenopause, uh, or even changes as far as insulin resistance or leptin resistance go.
So sometimes we need to take a look at those and we will order labs, of course, and take a detailed dive.
Okay. And so out of curiosity, when it comes to, um, hormones and testing for them. You know, obviously there's the, the allopathic world where it's blood is good enough, and then there's a lot of people who are hung up on the year end. A lot of people who are hung up on the saliva, um, do you marry all three worlds.
Where do you stand with that?[00:19:00]
I almost exclusively use just blood. And I'll tell you why. Uh, I started the first time I ever did like a hormone symposium. I wanna say it was 2015 and it was like one of a four m's, like big hormone symposiums. And you got exposed to everything. You got exposed to serum, you got exposed to you got exposed to urine.
And early on. I tried these different things as I got more experience in clinical practice prescribing hormones. I realized that if I just took a really good history and just did serum, sometimes I had a specific day in the cycle sometimes, not that I didn't need the other more expensive tests, and I could get a really good picture.
Just from those things. So I started to just back it down simplicity wise, and since I started doing that, I've been doing that approach for probably the last, I would say at least five or six years. I haven't, I haven't run a salivary test since probably 2017 or 2018. Um, since doing that, I [00:20:00] have not needed to run anything additional in patients to get their hormones managed and get results.
Awesome. That's great to hear. That's a really nice, um. So financially, uh, prudent and responsible approach
too, which is wonderful. 'cause those are usually covered by insurance for folks. So that's
a lot of the times, yes, or very inexpensive, maybe a hundred or $200 to get a really, really deep dive.
Mm-hmm. Um, so. Additionally, uh, talking about stem cell, you know, prep and really wanting to, uh, source from tissues that are not, you know, inflammatory adipose tissue. Um, you know, I, I'd wanna throw in here that, uh, a couple of episodes ago, or maybe it's in the future, haven't decided yet. Uh, we had Amy Anderson on who owns, uh, O2 and Light. She has a long history with Hyperbarics [00:21:00] and she was discussing how, hyperbaric therapy for, um, prep has shown, uh, a big, fold increase in harvesting stem cells from adipose tissues. So I was curious if you also knew of like any other tips or tricks on that front for really like optimizing your, your catch day.
Yeah, so Hyperbarics is great and the research is undeniable. You can absolutely get an increase in stem cell circulation, doing hyperbaric sessions. And I'd like to tell patients, 'cause people ask about it 'cause they've heard the same research. And my line with that is. It's within your means and you can do it financially.
You have the time to dedicate to doing it, by all means, go for it. But it's certainly not going to be, the biggest needle move so to speak. Like you're not going to make or break your treatment whether or not you have hyperbarics in there It's just a matter of can we do better? Sure.
The reason that I would even say something like that is because they have done [00:22:00] some studies on dose response levels with stem cells, and depending on the area that you're treating more isn't always better. You sometimes don't need as many stem cells it's not a matter of, oh, the most stem cells pack the most punch because just like any other cell, if there's no use for it, it's gonna go through something called apoptosis and it's just gonna die.
But one of the properties that stem cells actually do have is the property of self replication. So say you do put some in there and they realize that, there needs to be more of us to get this job done. They will self replicate. So again, we don't wanna put the body in a stressful state with too many stem cells where they have to undergo cell death.
We wanna put in kind of just enough. So again, the more is better argument isn't always there. That being said, we do actually encourage our patients to do some degree of intermittent fasting prior to their procedure so that we can get more stem cell release specifically from the adipose tissue so you can get more of that repair factor happening already.
Um, you get more into that autophagy state. And then another thing that we do during a lot of our [00:23:00] procedures is we will Actually administer NAD. So NAD is a co-factor that's already present in the body, and we shorten it to NAD because the name for it obnoxious. It stands for nicotinamide, adenine, dinucleotide for any other nerds out there.
And one of the things that NAD does is it does a process called mitophagy, which literally means the eating up of mitochondria or the death of mitochondria. And why this is important in the body, or at least in preparation for stem cells, is because Another way that stem cells work is that they actually have the ability to donate their mitochondria to cells in need.
So if they come across a cell that's in a zombie-like or senescent state, that's kind of just sucking up resources but not really doing anything, it can give it its mitochondria. That being said, we don't necessarily want to waste that ability on cells that we actually don't need. So we will give patients NAD to prep their body, clear out those mitochondria.
So now we have like a really fresh piece of soil. We want the seeds to go into an area without any weeds present that are gonna take up those resources.
Gotcha. So it almost sounds like there is [00:24:00] a balance leading up to this of that. Um. you know, autophagy fasting, and there's lots of different ways that people can get into that process, whether it's intermittent fasting or like, you know, five day low calorie, like two to 500. And there's systems out there that people can purchase.
I won't mention them here, that, can support people on that. But then it sounds like after the stem cells get in there, that's when also we really wanna get people into, um, that, Three grams three times a day to get into that buildup and repair.
Yes. Yeah, you actually wanna be doing that the entire time. But afterwards, we don't want any deficits, right? So we don't want the body to feel like it's not getting enough fuel in to do the healing you get into this really precarious situation where, well, you had this injury that your body didn't heal well the first time, and you wonder, well, why didn't it heal?
Probably because it didn't have the resources, it didn't have the time, or maybe something else happened that detracted the effort [00:25:00] away. We obviously wanna make sure we're covering all of our bases, that that doesn't happen again. And that's why we really do take what we're doing seriously, because we want people to get results.
Like, I'm the happiest if I never have to see somebody again, right? It means I did my job and, you know, I want people to get their lives back. I want them to be out of pain. I want them to really experience this power so that they tell all their friends and then we can keep doing what we love.
So then, am I understanding correctly that if you are the reason why intermittent investing is being chosen there is because you can trigger. autophagy, whatever people wanna say, and then miri. But you are also making sure that they are in that, protein buildup state. That muscle buildup state in preparation going into that.
So that's why it's IF rather than all out fasting.
Leaning up. Ah,
yes. So during the eating window, you wanna make sure that you're still getting in all the essential vitamins, minerals, nutrients that you need, that you're hitting that protein threshold. So we're really just [00:26:00] setting the body up to heal at this like wolverine level. Once we actually put the stem cells in there.
That's amazing. this is why I have this podcast is I want people to hear this and see this and just understand that behind the doctors that they meet and interact, it's just profound amount of learning and desire and drive. And you know, you only get to see snippets of one or a few hours at a time of understanding that this doctor has this grasp.
So, I mean, I'm just so happy that you're here and we're dialoguing with. So excited to get goosebumps over here. Um, what is potentially the most amazing improvement, uh, that you've seen in someone undergoing, um, stem cell? What was That holy shit moment where you're like, oh my God, this is crazy.
I can't believe this did this, and I believe it. So go for it. Let me, I wanna hear.
So over, I think since about 2020, um, I had the [00:27:00] pleasure of starting to treat a number of patients with a disease process called arachnoiditis. And for people that aren't familiar with what Arachnoiditis is, it has nothing to do with spiders. It has to do with something called the arachnoid layer that, uh, basically surrounds the spinal cord.
And these patients develop arachnoiditis for a number of different reasons. Uh, sometimes it's as simple as a woman receives an epidural during childbirth and she develops this scenario. Um, you can get it from any sort of real injury. And the, that layer of the spinal cord becomes inflamed and scar tissue actually starts to develop to the point where it can start tethering those nerves and the type of pain that people experience.
It is, it is probably one of the most painful disease processes that a person can go through. They often lose the ability to walk, they lose the ability to hold their urine, hold their stool, they lose sexual function. Um, they start getting neuropathy symptoms. It is just this drastic. Terrible downhill situation.
And I learned, uh, back [00:28:00] in 2019, a protocol from a, uh, a mentor of mine or colleague of mine. And in 2020 when Covid hit, he changed his entire practice and he started going more into covid research, stuff like that. And when he shut down, he started referring all these patients that were coming to him for that to my office.
And so I just got this influx and it was. Amazing because I really got to see at that point the power that stem cells can have. Because again, this being one of the most severe pain diseases in the world, and knowing that we were getting people better, and I'll give you a couple examples. I've had people be able to get a pain pump removed because they were no longer in pain.
And I'm talking the ones that were actually installed near the spine to continually deliver pain medications, get that removed. I had one gentleman and he's like, you know what? I just wanna be able to walk around the block. We got him up to walking three miles a day. I have had, I get goosebumps when I talk about it because, man, just giving somebody the ability to [00:29:00] walk back I get really emotional about this stuff.
Because it's so profound, you don't realize just how rough some people's lives are when they're impacted by pain and the things that we take for granted every single day that they're simply just not able to do. I mean, even giving somebody the ability, I've had people, get back their ability to urinate at will.
Not have to wear a catheter. And again, I get annoyed sometimes by having to go to the bathroom and I sometimes have to check myself, like I can choose when I want to use the restroom. So those, I would say are my most profound and most rewarding cases. And the cool thing with those cases, like I was explaining, it's we always get some results.
And this is why I also feel so confident with stem cell therapy and why I wish I could, you know, scream from rooftops all over the place because man. Like somebody's nagging knee is nowhere near as severe as the low back, but we can fix all of it, right? we can get people better and it's just incredible.
amazing. And you know, you also get to [00:30:00] circumvent. the opioid epidemic for many people. You know, like it's
just, there's so much there when it comes to chronic pain, uh, not only for the person, but then their social interactions and, um, yeah, it's amazing. It's not just movement of the joints, you know,
do wanna touch on the opioid thing for a second because this has been something that I had to, we'll say, learn the hard way. Um, we know that the opioids. Have caused a lot of problems socioeconomically, addiction wise, stress on the healthcare system, stress on families. I feel like I don't need to go there.
But one of the things that I've found, um, is that people who have taken opioids long-term for pain, their brain. Actually changes to some degree and they are no longer actually able to register if something positive changes in their body, maybe for a short term, but then the brain will actually recreate some sort of pain pathways to get the opioids back in the [00:31:00] system.
So. It's not say that we don't take patients who have been on opioids. We can, but we will work with you first to actually get you off of them for a good enough period of time that we feel the brain has had the ability to reset. And we do have some kind of tricks up our sleeve for, um, reestablishing that neuroplasticity so that when we do actually treat you with stem cells, we will get a response.
'cause the worst thing is that if somebody stays on opioids. We do the treatment, maybe they feel better initially because yes, of course you're gonna register the decrease in inflammation, there is gonna be changes actually happening. But then having the brain then override it so that it gets the opioids that it's seeking, it's just the most heartbreaking thing.
So, um, it's not, again, it's not to say that they're not a candidate, it's that other work has to be done first.
Right. And also I think you'd be the first to just reiterate this to people. It's not that we're saying that this research is in your head or you're drug seeking as it is. Literally, you have receptors in your body [00:32:00] that are reaching out and looking for this particular chemical.
And so, um, yeah, it's, a profound thing. That's absolutely a
profound thing. 'cause yeah, the nervous system. The nervous system's like Crazy and wired and um, gosh, that's big rabbit hole for sure. Thank you for
being succinct.
Yes.
Right, right. And it's always hard to cut them off too because it's, you know, we end up getting games of telephone that spread like wildfire on the internet and then suddenly you have
someone coming back and maybe, unfortunately misinterpreting at the hands of someone else.
So,
um, but nonetheless, it's wonderful that you have tools to work with people so that way they can become. Can for your service. Like
that's, that's great. That's wonderful. You're not leaving people empty handed on that front.
Mm-hmm.
So I also am curious about. So I'll come [00:33:00] out and say it. So when I, uh, had my two kiddos, we banked,
I said, oh, I'm gonna do a great thing.
I'm gonna bank these stem cells and, you know, maybe they'll 3D print a liver someday and it'll be great. Um, so I probably, uh, my first child's five and I didn't find out until they were pretty much five that I do not have access. To their stem cells, unless the stem cells are an FDA approved therapy and or it is a clinical trial that's being overseen, essentially registered clinical trial where they could be utilized.
And that floored me,
that just like. I was, I was so upset about it because knowing the, the vagaries that I know about the, the wonderful aspects of regenerative medicine, I was like, oh, wow. You know, like so many people in the family could potentially use these, and this will be a really [00:34:00] great investment only to find out that, like, you know, essentially should add a luck unless the FDA says it's akay.
So I am curious, uh, you know, if. Instances like that, if there are things, and you can go off here as long as you want. If there are things that you wish the general public knew about working with stem cells.
Yes. Well, let's have the cord bank conversation because I'm sure there's probably a mom or a dad listening right now who are like, wait, I can't get access. And I always hate being the messenger on this one because you feel that, sink, that heartbreak, like.
I paid all this money and I'm paying all these yearly fees and you mean to tell me that I can't use it And, I get it, I feel that sink for other people because, you know, it sucks. you feel like you've been had, you feel like you've been sold [00:35:00] and nobody likes that. And you know, it's probably in the fine print somewhere that we just, overlook.
We don't read terms and conditions come on now. nobody really does. eight to nine months pregnant when you're like, okay, just sign up. We gotta get the kit. So when we get the thing, we can go there. And yes, you're so focused on the collection, so I'm sorry to interrupt you, but yeah,
no one, I didn't read the fine print, whatever. So
anyway, my apologies for the interruption.
Yeah. And it's probably written in such legalese that it may not even have registered that that's what they're talking about. But to your point, if you were to bank a baby's cord blood, first of all. They're only going to release it to you under the care of a physician, and it usually actually requires multiple physicians to sign off on it and that you're using it for a study in a approved disease.
And if you guys are like, that's bs, I was told I can use it wherever, blah, blah, blah, blah. I would just urge you like, call the bank and just ask these basic questions like, Hey, what would it take for me to get a dose? Okay. And with [00:36:00] that. Odds are you may only get one dose. The banks are just storing it.
They're not growing it. They're not culturing it. They're not expanding it. And in general, one umbilical cord usually only contains about one to 3 million stem cells in the blood, I should say, right? Because this is cord blood banking. This isn't talking about the actual, like the Wharton's jelly, the jot is part of it.
This is the cord blood. So the cord blood, again, only about one to 3 million cells of the hematopoietic origin. And the hematopoietic basically means. Blood forming. So a lot of things that you might be able to use it for are things like the leukemia types of cancers. And this is really frustrating because, you know, not a lot of people are going to develop that for use.
Right. So it's not, to me it, it wasn't worth doing it and I didn't do it with my kids. And, um, I will preface with what I'm about to say with, I do have an affiliation with this company, but I sought out the affiliation. After it was something that I wanted. So there is a [00:37:00] company that is located in Florida and they actually will bank an umbilical cord.
They will grow culture and expand the cells and actually have doses that you can request at any point in time for whatever reason, as long as you have a physician that will administer it for you. And these are purified doses of real mesenchymal stem cells that are matched, of course, to the person that, you know, donated the cell to the child.
Uh, but that you could potentially also use in a first degree relative. So a parent, a sibling, uh, because. They are gonna likely have a lot of those same surface markers on the, the stem cells, which would allow them to, uh, be transplanted, you know, in a great way. So if I was gonna instruct people, if they wanted to have that sort of, we'll call it health insurance for the future and have stem cells readily accessible, I would go more towards something like that bank.
Um, and [00:38:00] if people want the link, I guess we can put it in the show notes or people can come to me. I don't love like sharing specific things. In the conversations, just in case stuff changes over time. You know, podcasts live forever. Companies don't always. Um, but in general, I have used this company and the other side to them 'cause they also have adult stem cell banking.
So I've used them for adult stem cell banking since I wanna say 20 18, 20 17 or 2018. And great longevity with them. Great experience with them. they have consistently been, um, just easy to work with and. Consistently good product, and I've been very happy with them. So if you are an adult, you can still actually bank your stem cells.
We can take them from your fat, take them from your bone marrow, and then you can have basically as many doses as you want available to you for the rest of your life. If you wanna do a dose a year, a couple times a year, if you get an injury, you can use it to treat it. It's, it's a pretty fantastic service.
So adult banking's possible, newborn banking is possible, but I also, I would not recommend what's currently available in those high pressure sales in the gynecologist's [00:39:00] office that, uh, they just try to guilt you into doing.
Yeah. Thank you. For sharing that. And um, I think one of my other follow up questions, I don't know if you're willing to dialogue
about this, but, um, how would I know to stay away from certain regenerative medicine practices? Like what
do I look for when I'm calling to ask for help? What's a red flag?
Um, I would say so. This is such a great question. One, I usually recommend finding places that that's what they specialize in. it's the whole jack of all trades, master of none sort of thing. You really want somewhere that. This is what they do, this is what they specialize in. This isn't just like an aside, uh, because unless you're really dedicated to the craft, I feel like there's a lot that you can miss when you're analyzing a patient's case, when you are selecting the proper injectable for treatments.
[00:40:00] The next thing that I would recommend is beware of marketing tactics. And it's not to say that somebody shouldn't be marketing to share about what they do, but as soon as you start finding a place that starts crapping on certain modalities, because they don't do them, to me, that's not a sign of a good, a good clinic, in my opinion, in my experience.
If a person or a provider legitimately offers regenerative medicine, they will be able to offer all of the tools in the toolbox because you know that not everything requires a hammer. So if you have places that are like, oh, we only use this type of birth tissue, or We only use this type, this thing, because we think it's the quote unquote best, well.
Doesn't mean that they may not be able to then create the perfect treatment plan for you, because certain tissues, certain structures, certain applications, it really does require figuring out, Hey, what is it that this patient actually needs? So no crapping on other things? No, just one tool in their toolbox and really, and again, making sure that they are taking the time to understand your case.
So if they're not sitting down with you and [00:41:00] saying, okay, what's going on? What type of pain do you have? And figuring out what the treatment plan should be. That's also a red flag. It's not just come in, we're gonna just shoot up the joint and send you home red flag on that one. Uh, and then the other aspect to that too is I would really encourage people to find a place that uses some sort of imaging guidance to direct the injections, especially when we're talking about precision things like injecting at the spine or something.
We wanna make sure that we're being as accurate and as careful as possible. So I say those, those would be my top things.
Okay. And it sounds like there's a lot more. Um, but
There's a lot of nuance, you know? And the other basic thing too is just like, who you vibe with. Like, I'm certainly not gonna be the person that people vibe with all the time. Some people really just love the idea of like a 50-year-old male doctor being the one that treats them right. That's not me. You know?
Um, and that's cool. Like I, I'm totally cool with that. But yeah, find somebody that you vibe with. 'cause you're just gonna have a better doctor patient relationship and you're gonna feel more comfortable under their care, which. There is an argument for that [00:42:00] therapeutic relationship.
Gotcha, gotcha. So we've talked a lot about stem cells and I was wondering if you could give a 20,000 foot view on exosomes. What are they? What do they do? How do we use 'em?
Exosomes are stem cell secretions. And they really became popular, oh gosh, I would say probably about six or seven years ago when this one company, utilized them in a very, very big way to heal this guy's incredible third degree burns on its face within a very, very short period of time. And what had happened was this PhD, he had taken some stem cells, put them in a medium.
Allowed them to kind of like release things that they were gonna release and then collected that medium and applied that to the patient. And what he realized was that what the stem cells were doing was they were releasing their exosomes. And exosomes are, we'll call them like communication bubbles.
Like if we were to put those talking bubbles above our heads and like those words were coming out, that's what an exosome would kind of be. [00:43:00] So, you know, if I am yelling at you, if I'm speaking kindly to you, if I'm singing you a song, right? So. That's what exosomes are. They're carrying a message and they're carrying a specific message, and sometimes exosomes, well, at least previously, a lot of what people thought exosomes were was just trash being removed from the cell, right?
Same as me, just like telling you off, like whatever. Um, but what we also realized is that stem cells could be communicating really beneficial things. They can be telling you to reduce inflammation. They could be telling you to, Hey, release some stem cells from this point. And that's what kind of became of this field.
Now, they're great for the one piece of information that they're going to deliver. So they can work hard and fast. They don't have the same longevity that stem cells do. So stem cells, they, of course, they have that ability to self replicate that we kind of talked about earlier. They can implant, they can stay in a spot for anywhere from six months to a year, depending on what research you're looking at.
Exosomes. They go in, they hit their target, they're gone. Really great as an [00:44:00] addition to treatment, especially in patients that are very, very hot and inflamed. We can kind of just like settle things down really nicely, give the stem cells a little bit of an easier space to work in. Um, but I don't usually love using them as a standalone treatment because of the shortness of their action.
Okay. Wow, I appreciate that. That's a very. Simple, simply put for people to understand a great definition there. Um, I'm trying to think if there's anything else. I Oh yeah, obviously. So, uh, you know, this is the Life After Mold podcast, and of course, uh, you know, when we think of, uh, mold and mold exposure, we know that there are.
You know, the carbohydrates and the proteins of the organism, the mold itself, that can cause, uh, systemic, uh. Inflammation, chaos, immune system, chaos. Uh, we also know that the toxins they produce can also cause a lot of that immune system [00:45:00] chaos, but they can also lead to oxidative damage and specifically lipid peroxidation.
And the problem with that, of course, is all of our cells that outer coating are made of our. Bilipid membrane and our organelles inside, including our mitochondria, have that lipid membrane. And so, or many of our organelles, I might be flubbing on a couple of things, but on the ribosome, who knows. But anyway, mitochondria, that's what I'm getting at.
And those are the, the energy producers of the cells. And we see that when people are mycotoxin exposed, they really tend to have, um. A lot of damage to the tissues that are rich in mitochondria.
And so I am curious about, um, you know, what role do you see stem cell therapy or, uh, just in general origin of medicine or some of the work that [00:46:00] you do?
What role? Do you see it with regards to mold illness? And I would say the follow up to that would be timing. During, after, you know, where, where, where would you place that for us?
One of the cool things about stem cells is their ability to actually positively impact a patient's immune system. And I'm sure I'm like preaching to the choir on this and you, you obviously know this about like my personal life and history, but we were in a mold house and my husband had a brutal experience with it, to the point where we're still kind of dealing with some stuff with his health.
In regards to the mold exposure, um, I'm perfectly fine. Like I really didn't have any symptoms or whatnot. And, uh, you know, there's obviously genetic differences there. You know, I would argue maybe our exposure level was different, who really knows, but immune function could be at the root of that.
And there are various things that obviously impact a person's immune function. Everything from whether you were born vaginally or c-section, whether you [00:47:00] were breastfed, whether you received antibiotics at a young age, whether you had childhood trauma it spans, right? It spans. And if we're going to, you know, split hairs on mine and my husband's, you know, how we grew up, there are some differences there, right?
And genes are different. He happens to have the, you know, some M-T-H-F-R defects, whereas I don't, so I naturally will detox better and all that good stuff. One of the things that the stem cells can do positively in those populations that are maybe more responsive to mold illness, so to speak, is they can positively impact the immune system.
They can actually stimulate the thys plan to produce immature T cells, and they can balance those th one versus th two responses. So we've actually even used stem cells in patients with autoimmune diseases and have had some autoimmune diseases go into remission for very long periods of time. Again, not ever promoting it's secure or anything like that.
We have seen clinically significant evidence of remission in everything from Sjogren's to ms, to rheumatoid [00:48:00] arthritis, to Hashimoto's. Um, and then of course we have tested things in my husband and he did really great after a, a treatment with some bone marrow stem cells. And it's just, it's, it's another tool in the toolbox, right?
So We did my husband's treatment after we were out of the mold house, while he was still doing some other stuff. So he was taking some antifungals, uh, but it was also prior to him having to get a, uh, sinus surgery where there was actually a walled off infection in there.
And oh my goodness, girl, you should see the biofilms that have come outta this thing. I feel like you would nerd out on it just as much
Yeah. No. we'll have some fun on that later for sure.
Uh, but it's, it's just phenomenal what has come out of that site. But I think that there was, of course, a limitation to what the stem cells could do, knowing that even though he was out of the exposure, there was still a consistent internal exposure happening because it was walled off right.
Now. Not to say that it didn't help, of course it's gonna amp up the immune system.
You're gonna get a lot of healing. Pair happen throughout the whole entire body because they're, they're never not gonna do [00:49:00] nothing. They're always gonna go after something. So how often are we aware of our liver or our kidneys or our, you know, even our gut lining or our myocardium, like, we just aren't aware of them.
But that doesn't mean that they can't go and. Start to heal and repair those areas. Um, during exposure, if a person has the desire and the means, I would say it'd be worth a shot to at least bolster the system and start to repair stuff. But again, as long as there's that consistent exposure, you're still gonna be putting consistent stress on the body.
So that might not be the best timing for it, but if you can't get out, it actually may be worth it in that scenario Consider banking yourselves so that you could have doses kind of ready when you need them, and really just play that game of palliation.
There's one follow up question I had with regards to that. So I'm assuming that, when we're doing things for. Autoimmune support or for the th one, th two balancing, which I'm so excited about. how are the stem cells, being provided? Like, [00:50:00] what is the vehicle for that?
Is it injection, is it nasal spray, or what does that look like?
We would usually do an IV administration so that they can go systemic. there is the ability to do things like an intranasal administration. We use a tool called a s pheno cath, and it's just this gentle little catheter that we would actually place right back at the s pheno palatine ganglia.
And that can allow some transfer through the blood-brain barrier, at least by the exosomes that are created. Um, and then we can also do nebulizer treatments too. So you can actually do an inhalation, especially if there's a lot of, uh, deep lung involvement. So nebulizing, something like exosomes could be beneficial for that.
Gotcha, gotcha. And in this whole process, do you find that there is a balancing of the sympathetic, parasympathetic nervous system that. Can occur with stem cell use, and if so, are there certain procedures that delivering them in certain areas, maybe in and around like vagal ganglia [00:51:00] or things like this off, off
no. it's such an interesting point. So we do take nervous system health as seriously as we can without forcing people to do things they might not be comfortable with. Right? 'cause not everybody's ready to have that nervous system conversation. But one of the things that we touch on in our online portal for patients is actually simply your mindset.
If you have a mindset conducive to healing, you are more likely to heal. Versus somebody that might be stuck in a victim state or thinking that they can't get better, it has a lot to do with it. So we actually take people through an exercise that's based in a combination of, Dr.
Joe Dispenza's work and Dr. Bruce Lipton's work, and it actually helps you retrain how you're talking to your body because every cell is listening to every single thought at every point in time. So we really need to get that changed up. And sometimes just those little shifts. Can actually start to put the nervous system into more of a calm and relaxed state with that.
The other thing that we utilize during, the day of the treatment. Is, flower essences. So a lot of us learned about the [00:52:00] Bach flower essences when we were in school, especially as naturopathic doctors. A lot of people see them in like sprouts or Whole Foods. we actually have another company that we use, and they are, actually local here in Phoenix.
Uh, but anybody can buy them all over the place. And before the procedure, we actually have them do the flower test to see what one they're resonating with, to actually help them get into even a more relaxed and healing state prior to us doing everything else so that we can kind of just bring everything into harmony.
Uh, but we definitely do encourage kind of stress reduction techniques, meditation, mindfulness, and there's a whole host of things that we take people through.
Tons, tons of stuff out there, and I always tell people, you know, when you are neurodivergent or you're on the spectrum. Meditation or visualization might not be your jam. And in that case, there are tons of wonderful tools that are almost like biohacking tools. I'm not a fan of the term,
but like where you can like activate that parasympathetic nervous system without having to use. [00:53:00] Your rational mind to do it. So, um, yeah, and the black flowers remedies are an amazing use. That's wonderful. Um, now as we're wrapping up, do you feel like there's anything else that you wanna share? Do you have any words of wisdom or hope for people navigating complex chronic illness like mold exposure or, you know, chronic pain resulting from mold exposure or, you know, just any thoughts?
I think the biggest thing, you know, working with patients of this population in general is just always having hope that there's going to be something that helps you. Um, I don't know if you ever got the pleasure of hearing Dr. Jim Seig speak, but I remember hearing him one time, he said, there's no such thing as an incurable disease, but there are incurable patients, which to me also reversely translated to.
Every disease can be curable and most patients can be cured. So [00:54:00] part of it, like I was saying, it's the mindset of allowing yourself this ability to hope and to find resources and to seek people out, and to really just investigate these things that might help you. And the other side of that, just being the practical side, like just 'cause the FDA doesn't approve it, doesn't mean it's bs.
I feel like a lot of people get so hung up on, it's not FDA approved. It doesn't have this stamp of approval. It doesn't mean that it doesn't work. People get healing from so many different things. I mean, you hear people talking about healing with B venom or frog poison, like anything can be a tool.
Right, right. Absolutely. And the reminder too, that our supplements. Not FDA approved and yet they do an amazing job. So it doesn't have to be, you know, something like the frog venom or B venom therapy and like, just the perfect example is that our supplement industry is largely unregulated by the FDA, other than a random act from 1994.
But I won't get into that right now. So, um. This has been [00:55:00] an incredible wealth of information and I know I could just sit here and continually pick your brain for hours on end. Um, but I know that you have wonderful things to do, people to help, and a beautiful family to attend to. So, um. With all of that being said, do you have anything else you'd like to share with folks?
How people can find you? Anything on the horizon? I know that you're an amazing teacher and you'll have programs every now and then that you offer, so feel free to to share any of that.
Oh, thank you. Um, I'm most active on Instagram, if you wanna find me there. So I'm just at Dr. Sot, D-R-S-O-L-T. Uh, clinic website is stem cell therapy pro.com. Best way to inquire about. Working together, programs we offer, things like that is actually just to contact my office. Uh, my assistant handles pretty much all of those questions and inquiries, scheduling, onboarding, all of that good stuff.
And as far as on the horizon, I mean, it is my goal to start [00:56:00] making more informational YouTube videos, uh, so I can just start teaching a lot more of this stuff to people. 'cause you're right, like there's just wild things that live in my brain that I think we just need to get out into the ether to benefit people.
'cause not everybody has the, the means and whatnot to, or the desire to even work one-on-one with somebody. So the more I can put out there, I think the more people I can help.
Yeah. Well thank you so much. I have so much love for you and I look forward to seeing you again hopefully soon.
Um, yeah,
Thank you.
for everyone for tuning in and definitely go connect online with Dr. Solt and, uh, get better. [00:57:00]
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