Less of You: Life on Semaglutide & Tirzepatide - podcast cover

Less of You: Life on Semaglutide & Tirzepatide

Eva Sheie & Kami Gamlemwww.lessofyou.com
Eva + Kami are two old-ish moms kids confronting our reasons for being obese while losing weight on semaglutide and tirzepatide, and roasting our past selves. Sarcasm is our happy place. Follow us on Instagram @lessofyoupodcast. 

After a friend (who is a plastic surgeon) talked Eva into starting semaglutide in February of 2023, she lost 70 pounds in 14 months, alternating between long stretches of being stalled at the same weight and consistent but slow weight loss.  Chasing a lifelong dream to being considered just overweight and not obese by the BMI calculator, after 14 months Eva switched to tirzepatide to try and reach a goal that still seems just out of reach.
 
A prolific eater of her feelings, Kami was tired of being uncomfortable and when she heard through a mutual friend how semaglutide had changed Eva’s life, she found a trusted medical weight loss provider and took the first step. 

As Kami starts her life on semaglutide, Eva adjusts to a world with less food noise and figures out how to let go of the crippling negative self-talk. 

On each episode, we connect on how our lives are changing in real time as semaglutide and tirzepatide help us be smaller people, and try to answer the bigger question for ourselves: 

When there’s less of you, what is left?
Last refreshed:
Follow this podcast in the Metacast mobile app to refresh it and see new episodes.
Download Metacast podcast app
Podcasts are better in Metacast mobile app
Don't just listen to podcasts. Learn from them with transcripts, summaries, and chapters for every episode. Skim, search, and bookmark insights. Learn more

Episodes

Not-So Texas Roadhouses

Kami forgets to track her calories and take her meds. Eva sends her daughter to camp and Kami remembers getting left behind at camp at age 12, back when there were no cell phones. Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. Are you confronting the same challenges? We’d love to hear your story. Send an email to podcasts@theaxis.io. To help others find great res...

Jun 20, 202530 minSeason 1Ep. 28

Muffin Top, Sleep Apnea, Payment Plans

Eva gained a few pounds back and got a muffin top. Kami vs. insurance: It should not be this hard to get sleep apnea treatment. Yep, you can get a payment plan for weight loss meds. Because results shouldn’t depend on your wallet crying. Learn more about PatientFi ! Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. Are you confronting the same challenges? We’d love ...

May 23, 202535 minSeason 1Ep. 27

No I Don’t Feel Totally Different Now

Kami broke her foot, and can’t move. Eva ate 4 dark chocolate mini eggs and got sick (4 eggs, not 4 bags of eggs). We beat the question “Don’t you feel totally different now?” to death. Kami SW 250, CW 198, GW 150? Eva SW 280, CW 184, GW 170 Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. Are you confronting the same challenges? We’d love to hear your story. Send ...

Apr 25, 202521 minSeason 1Ep. 26

Teetering on the Edge of One-derland

Kami finally busted through the plateau, now hovering at 200 at officially down 50 lbs. Eva’s creeping toward 100 lbs lost, and had to try on size 8 jeans for the first time since 5th grade. For the record, yes, we’ve lost weight, but we’re still the same people on the inside. Stop asking if we “feel great.” We love that we’re inspiring people to take the plunge! Shoutout to @jennpurrr on Instagram for letting us know we’re the reason she started. See the Nurri protein shakes from Costco Listen ...

Mar 14, 202524 minSeason 1Ep. 25

The GLP-1 and addiction connection no one’s talking about with Dr. Jason Giles

In this special bonus episode, an excerpt from a conversation with Los Angeles Addictionologist Dr. Jason Giles about the potential for GLP-1s as a treatment for substance abuse, explaining their impact on cravings and brain chemistry. Dr. Giles candidly shares his own journey with addiction, how he overcame it, and how it led him to specialize in addiction medicine. Learn more about Los Angeles addictionologist Dr. Jason Giles Eva + Kami are two old-ish moms with little kids confronting our rea...

Mar 07, 202546 min

Debra’s 6 month progress update & tips for those with only 15 lbs to lose

The Debra returns with a progress update and fills in for Kami, who’s out with the flu. She started at 168, now at 154, aiming for 150. It took almost two months before the scale even moved, but she stuck with it. Hear Debra’s thoughtful tips if you’re thinking about using a GLP-1 to lose weight, and why you should be careful who you tell. Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarc...

Feb 14, 202517 minSeason 1Ep. 24

Possibly The Worst Before Photo Ever

Kami stalls at 203 and wonders if it’s time for a higher dose to make it to one-derland. Eva shares a jaw-dropping “before” pic from August 2021 after eating at Paula Deen’s while in Nashville. Meet Eva’s doctor, Austin plastic surgeon Dr. Johnny Franco Kami SW 250, CW 203, GW 150? Eva SW 280, CW 189, GW Just Overweight Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy pla...

Jan 31, 202527 minSeason 1Ep. 23

Tips for Newbies: Getting Started on Semaglutide and Tirzepatide

New to semaglutide or tirzepatide? Here are our tips for what to expect when you are just getting started. We survived the mountains of Christmas food and Eva let a wardrobe stylist give her closet a full makeover. Kami SW 250, CW 205, GW 150? Eva SW 280, CW 194, GW 170? Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. Are you confronting the same challenges? We’d ...

Jan 03, 202534 minSeason 1Ep. 22

Even More Rear End Problems

Thanksgiving chaos update, questionable ingredients brought by in-laws, a recurrence of rear-end issues, and how Eva got peer-pressured into tucking in a shirt. Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. Are you confronting the same challenges? We’d love to hear your story. Send an email to podcasts@theaxis.io. To help others find great resources for GLP-1 me...

Dec 13, 202429 minSeason 1Ep. 21

If your weight loss progress is stalled on a GLP-1, here’s my advice

Eva has lost 90 lbs, the equivalent of 9 gallons of paint according to the Lose It! app. It’s Kami’s birthday and she makes big plans for the night. An old friend reaches out at the end of her 2nd month of semaglutide injections with questions about stalled progress. Kami SW 250, CW 207, GW 150? Eva SW 280, CW 189, GW 170? Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy ...

Nov 29, 202425 minSeason 1Ep. 20

No plans to binge

Still blowing money on groceries we end up tossing, planning the menu for Thanksgiving but not planning to binge eat, and excited to have full houses. Somehow 100 people subscribed to us on YouTube. We don’t know why, but thanks! Here’s where to subscribe if you haven’t already. Kami SW 250, CW 211, GW 150? Eva SW 280, CW 192, GW 175 Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is...

Nov 15, 202435 minSeason 1Ep. 19

This is Halloween

Eva feels fat and to feel better tries on the largest jeans she ever owned (size 20W). Kami gives a fire recovery update while wearing a fox costume for Halloween. Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. Are you confronting the same challenges? We’d love to hear your story. Send an email to podcasts@theaxis.io. To help others find great resources for GLP-1...

Nov 08, 202431 minSeason 1Ep. 18

Life keeps happening

Kami’s 92-year-old neighbor’s house burns down, the 2nd fire in a year of serving on the HOA board. Eva forgets a full order of groceries in the car on a 90-degree day. Life keeps happening, the only difference is that now we forget to eat. Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. Are you confronting the same challenges? We’d love to hear your story. Send a...

Nov 01, 202435 minSeason 1Ep. 17

It’s just a number, it doesn’t mean anything

Weigh yourself every day. Don’t weigh yourself every day. Only weigh yourself at the weigh-in. Weigh yourself in the morning after you go to the bathroom. Always weigh yourself at the same time every day. Take off your shoes. Don’t wear jeans to the weigh-in. Don’t drink a lot of water on your weigh-in day. Weigh in on Friday so you can cheat on the weekend. Go to your weigh-in in the morning and not the evening. You can eat whatever you want on cheat day. I only ate zero point food all week. I ...

Oct 28, 202432 minSeason 1Ep. 16

Oat-zempic

Eva's 30 year high school reunion approaches with the same worries as high school, including what to wear and who will I know? Kami’s in full freak-out mode after watching the Oprah special on AI and hearing about scammers using AI to mimic voices. Then there’s the whole "Oatzempic" thing blowing up TikTok with oat-based smoothies, which sound disgusting. Kami promises to be brave and try this weird drink so you don’t have to. Read MedScape’s How 'Oatzempic' Stacks up to Ozempic Watch Oprah’s AI...

Oct 04, 202429 minSeason 1Ep. 15

Body dysmorphia, self-injecting B12 & The Debra makes an appearance (Kami’s mom)

Kami’s mom Debra joins with her own skinny shot update after 8 weeks. Kami’s endocrinologist breaks up with her because her thyroid is perfect. Eva worries about a compounded tirzepatide becoming unavailable and attempts to stockpile shots. The viral cookbook: What to Cook When You Don't Feel Like Cooking by Caroline Chambers Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our hap...

Sep 20, 202442 minSeason 1Ep. 14

Making weight loss medication affordable in Indiana with Cassie Layne, FNP [BONUS]

Because Cassie Layne, FNP, knows the struggle of dealing with weight firsthand, she’s dedicated to making health and wellness accessible for everyone. In just over two years, she’s helped over 5,000 people from across all of Indiana reach their weight loss goals with affordable semaglutide for just $98 a month. One of those people is our very own Kami, the co-host of Less of You! Cassie shares inspiring success stories and clears up common misconceptions about these medications. Learn more about...

Sep 06, 202414 min

The MexiMelt is Coming Back

Taco Bell’s Meximelt is coming back. Eva’s eyesight improves instead of getting worse for the first time since 8th grade. Kami catches a Facebook Marketplace scammer red-handed. Semaglutide combined with Kami’s appetite suppressing ADHD medication is lowering her already low blood pressure. Kami SW 250, CW 221, GW 150? Eva SW 280, CW 195, GW 170 Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves...

Aug 30, 202425 minSeason 1Ep. 13

Transportation and vacation

Kami’s daughter’s school bus keeps skipping her stop in the morning. She gets a new job but is then un-hired two days later. While on family vacation in Washington, Eva learns the hard way not to eat Red Vines. Want your own Less of You sticker? DM us on IG @lessofyoupodcast with your mailing address. Kami SW 250, CW 222, GW 150? Eva SW 280, CW 196, GW 170 Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our ...

Aug 16, 202426 minSeason 1Ep. 12

Quit the medication so you can eat again

Kami’s job as HOA president takes a stressful turn as she fights with State Farm to get construction moved forward on the 4 houses that burned down over a year ago. Eva self-diagnoses a bizarre new side effect of weight loss by reading Reddit comments, and shares an update on the subpoena from our previous episode. To help others find great resources for GLP-1 medical weight loss programs, our new list of trusted semaglutide and tirzepatide providers is live & being updated regularly at less...

Aug 02, 202425 minSeason 1Ep. 11

Insurance coverage, bowel obstruction, stomach paralysis, and SO much more with Dr. Sulagna Misra [BONUS]

After losing more than 70 lbs herself, Dr. Sulagna Misra changed her life and now uses her experience to help others do the same. Dr. Misra shares her personal weight loss journey, the side effects of GLP-1 she’s experienced personally as well as those her patients have experienced. Links Misra Wellness Direct Physician Care in Encino, California Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selve...

Jul 26, 202429 min

More Rear End Problems

Continuing our unintentional rear-end-themed mini series with a fissure while on vacation. Is all the weird stuff we talk about helping anyone? Please tell us if it is. The murder that made Eva promise to never do nothing again, if you’re curious: https://www.startribune.com/stephen-allwine-found-guilty-of-killing-his-wife-staging-death-as-suicide/471981953/ Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting ou...

Jul 12, 202423 minSeason 1Ep. 10

Meet the legend, Dr. Johnny Franco! [BONUS]

Meet the man, the doctor, the legend, who heard about semaglutide and then took it himself, losing over 70 lbs. Realizing his success would help thousands of others change their lives too, he then made semaglutide easily accessible and affordable to his own patients in Austin and San Antonio. In this clip from the Meet the Doctor podcast, Eva chats with Austin plastic surgeon Dr. Johnny Franco, the doctor who introduced her to the skinny shot. Listen to the full interview with Austin plastic sur...

Jul 10, 202414 min

Shit My Pants

After Kami forgot her medication at home (again) and didn’t have medication for 20 days, she invented her own plan for restarting and discovered the consequences. Eva gets invited to a patient appreciation pool party by a plastic surgeon’s marketing team and now has to decide 1) whether to go and 2) whether to swim at said party. Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our...

Jun 28, 202424 minSeason 1Ep. 9

Finding One-derland

Kami leaves for a 3+ week trip to Washington and forgets her meds at home and rediscovers the effects of marijuana, while Eva finally reaches the magical place called One-derland and schedules laser treatment to reveal that her legs do still exist and can be exposed to natural light. Kami SW 250, CW 225, GW 150? Eva SW 280, CW 199, GW 180 A New Drug Switched Off My Appetite. What’s Left? Wired Magazine The most exceptional laser specialist anywhere Jenny Burnley @Restored by Jenny Eva + Kami are...

Jun 14, 202421 minSeason 1Ep. 8

Please don’t take my drugs away

Finally switching to tirzepatide after 4 months of stalled progress, Eva is quickly approaching “one-derland.” Kami learns that the voices in her head are actually just food noise. Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. Are you confronting the same challenges? We’d love to hear your story. Send an email to podcasts@theaxis.io. To learn more about sponsori...

May 31, 202429 minSeason 1Ep. 7

Trying on Swimsuits is Fun?

Kami fails to prepare for a long trip out of town and runs out of medication. Eva complains about random things like compliments from other people and ponders what might be a side effect. Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. Are you confronting the same challenges? We’d love to hear your story. Send an email to podcasts@theaxis.io. To learn more about s...

May 17, 202422 minSeason 1Ep. 6

My Vacation from the Medication

Discussing the reactions to photos posted online, getting hit on by a lady valet while parking at SXSW, and whether or not it’s a good idea to take a break from the medication while on vacation so you can eat whatever TF you want. Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. Follow us on Instagram @lessofyoupodcast Host: Eva Sheie & Kami Gamlem Assistant Pr...

May 03, 202418 minSeason 1Ep. 5

My Life Goal Is To Be Just Overweight

In the six weeks since Kami started semaglutide, she’s lost more weight than expected and describes the handful of side effects she’s experienced so far. Eva complains about the odd phenomenon of people asking “so are you done?” despite still being obese. Kami - SW 250, CW 235, GW 150? Eva - SW 280, CW 210, GW Just Overweight Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our hap...

Apr 19, 202423 minSeason 1Ep. 4

Rule #373: Only take photos from 6 feet above

On the mind games of how, when, and who we can take photos with and why… and what inspired (forced) Eva to finally share her previously unseen before and after photos with the world. And did the circumference of Eva’s head actually get smaller? Is that even possible? Eva + Kami are two old-ish moms with little kids confronting our reasons for being obese while losing weight on semaglutide and roasting our past selves. Sarcasm is our happy place. Are you confronting the same challenges? We’d love...

Apr 08, 202419 minSeason 1Ep. 3
For the best experience, listen in Metacast app for iOS or Android