Troponin I (cTNL) Lab Values
Jul 17, 2023•3 min
Episode description
Overview
- Troponin I
- Normal value range
- Pathophysiology
- Special considerations
- Elevations in lab values
- Normal value range
- Typically, less than 0.035 ng/mL or less
- Can vary among institutions
- Has to be greater than the 99th percentile
- Pathophysiology
- Troponin is released during myocardial cell damage
- Decreased perfusion causes myocardial cell damage
- Causes of myocardial cell damage
- Myocardial infarction
- Demand ischemia
- Cardiogenic
- ACS
- Noncardiogenic
- Sepsis
- Renal failure
- Extreme exercise
- Cardiogenic
- Special considerations
- Submitted in green top tube
- Value peak
- Detection 6-12 hours after acute injury
- Peaks 24 hours after injury
- Can stay elevated for a week
- Knowing patient history is critical
- Increased values
- Any elevated value is typically considered critical
- Acute elevations warrant immediate investigation
- Typically PCI (percutaneous coronary intervention)/Angiography and EKG to rule out MI or ACS (acute coronary syndrome)
- Other elevations
- CABG
- Extreme exercise
- End Stage Renal Failure
- Assess for:
- Acute chest pain
- Symptoms of MI
- Nausea
- Vomiting
- Angina in any form
- Reflux (especially in women)
- EKG
- Angiography or PCI
- Management of non-cardiogenic etiology
- Lab Values
- Perfusion
- Educate patient on keeping history of elevated levels or cardiac disease for future reference
- Educate patient on duration of elevated troponin levels, post injury
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