Glycosylated Hemoglobin(HgbA1c) Lab Values - podcast episode cover
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Episode description

Normal 5.6-7.5 % of total Hgb

Indications

  • Assess control of blood sugars over a several month time frame
  • Diagnose Diabetes Mellitus (DM)

Description

Glycosylated Hemoglobin (HbA1c) is the combination of glucose and hemoglobin. When glucose is elevated in the blood the amount of glycosylated hemoglobin increases proportionally. A red blood cells lifespan is about 4 months, so you can get an idea of blood sugar control over the last several months.

What would cause increased levels?

  • Poorly controlled Diabetes Mellitus(DM)
  • Non-Diabetic Hyperglycemia:
    • Stress
    • Cushing Syndrome
    • Pheochromocytoma
    • Corticosteroid Therapy

What would cause decreased levels?

  • Renal failure
  • Blood loss
  • Hemolytic anemia
  • Sickle cell anemia
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