Timestamps: 00:00 Intro 00:44 With this latest outbreak of the Delta variant with COVID-19, are laboratorians still working on new innovations for COVID? 02:23 Could you go into more detail, elaborate for us about this COVID-19 innovation around sequencing? 04:25 Could you help us understand a little bit on what work is being done in those areas? 07:47 Could you help our audience understand what have these conversation been like now that we’re into this pandemic this far, and the way that labora...
Aug 20, 2021•15 min•Ep. 41
Timestamps: 00:00 Intro 01:05 From your perspective, why is the blood inventory important to a hospital? 04:17 What have you learned about managing a hospital’s blood inventory these past 18 months or so? 08:09 I was wondering if you could give us a specific example on how are they trying to bridge that gap? 08:55 Can you explain who the Dream Team is? 12:34 How does PVM look different on the hospital side? How is that being worked? 16:33 How might physicians, non-pathologists, help their hospit...
Aug 06, 2021•22 min•Ep. 40
Timestamps: 00:00 Intro 02:15 Why is it not enough for learners just to focus on the curriculum of their program? 04:30 What are two or three things that learners should pay attention to during their training? 07:19 Paying attention to the habits of our mentors and understanding that those habits are what is reassuring them, that is a key source for their confidence in their clinical practice. What’s another thing? 09:50 Do you have a third one that we should pay attention to? 12:45 How could le...
Jul 23, 2021•25 min•Ep. 39
Timestamps: 00:00 Intro 01:19 Could you help us understand, why should I consider getting an ethics consult? What value could this bring to my clinical practice? 07:49 What should our audience understand in order to really work better with our local med ethics team? 13:58 Could you help us understand about organizational ethics? How does that compare and contrast with that hospital ethics committee that you said everybody has and are most used to turning to? 22:24 What would be your recommendati...
Jul 09, 2021•26 min•Ep. 38
Timestamps: 00:00 Intro 00:45 Why is it important to perform molecular testing on solid tumors? 02:47 What is the significance of this testing for the patients and physicians? 07:18 Can you share with us, what are some recent examples that have blown this door open about hereditary oncology? 10:28 Can you talk a little bit about the challenge on how do we get the rapid rise in molecular knowledge and testing? What is your perspective? 15:25 Can you elaborate a little bit on how you interact with...
Jun 18, 2021•21 min•Ep. 37
Timestamps: 00:00 Intro 01:11 What are frozen sections, and why are they an important part of patient care? 04:50 What are some of the challenges of actually performing a frozen section diagnosis? 07:03 How has frozen section changed in recent years, or over the course of practice? Has it been practiced similarly over the years, and are there differences in frozen section practice in different hospitals? 14:37 Given this uptick in the complexity of cases, how do you mentor people who are trying ...
Jun 04, 2021•25 min•Ep. 36
Timestamps: 00:00 Intro 01:00 How does the cardiovascular laboratory support patient care? 01:47 Can you tell us a bit about ceramides? What are they? 04:14 When should ceramides be tested? 06:04 Can you modify someone’s ceramides such that the test can be repeated and monitored, or is it once in a lifetime because ceramides or more static? 08:05 What is the controversary around ceramides? 09:52 Could you give our listeners an introduction to Lipoprotein(a)? 11:45 Who should be tested for Lipopr...
May 21, 2021•19 min•Ep. 35
Timestamps: 00:00 Intro 01:00 Can you give us the lay of the land and explain how does the cardiovascular laboratory provide patient care? 03:24 Can you elaborate for us what it looks like when you have clinical chemists, cardiologists, and other professionals with different backgrounds working together? 05:56 Can you talk about bringing these people into the laboratory and developing a test that provides a lot of value to patients? How is that blended and what’s the output? 07:31 Talking about ...
May 07, 2021•19 min•Ep. 34
00:00 Intro 01:15 What’s your origin story? How did you become a forensic pathologist? 03:53 What are some of the misconceptions about forensic pathology? 06:15 Is there a big public health component to forensic pathology? 07:29 Covid is a nice example on how you have partnered with public health, can you elaborate more on that? 10:15 What other types of physicians are you interacting with periodically and what are those conversations about? 13:10 Do you approach autopsies differently depending ...
Apr 16, 2021•21 min•Ep. 33
Timestamps: 00:00 Intro 01:29 Why is it really important for leaders in our practice to really understand quality for clinical practice? 03:13 What are the latest developments in your area of clinical laboratory medicine? 06:01 In recent years, what have we learned about quality and how we do quality in the hospital? 11:19 How do we actually implement this in clinical practice for success, for sustainability? You talked about putting together an interdisciplinary team. What’s the secret sauce fo...
Apr 02, 2021•24 min•Ep. 32
00:00 Intro 00:40 Can you tell us how your roles in these different laboratories support testing for patient care? 03:13 What are the latest developments in your area of clinical laboratory medicine? 07:22 Can you elaborate a little bit about this new approach that you have developed is able to bring both sensitivity and specificity along? 10:55 Putting the interpretation on the form, you are probably experiencing quite a few phone calls with our clinical colleges. Can you talk to us about how t...
Mar 19, 2021•23 min•Ep. 31
Timestamps: 00:00 Intro 01:07 Why is transfusion support an especially important component of patient care for patients that are on ECMO support? 03:24 Are there some principles that we can think about that will help us better understand transfusion decisions in these patients? 05:52 Can you take us through some specific situations that might help our listeners get our hands around (DO2 and VO2) from a practical standpoint? 10:31 How can laboratory professionals add value to the clinical care of...
Mar 05, 2021•18 min•Ep. 30
Timestamps: 00:00 Intro 01:11 As a critical care physician, why is laboratory testing important for your practice? 04:09 What do you wish lab medicine folks understood better about critical care medicine? 08:19 What would be your advice to a laboratory medical professional that’s interested in developing a better understanding of critical care medicine? 14:51 What do you see for the future collaboration between laboratory medicine and critical care practice? 16:44 Outro...
Feb 19, 2021•17 min•Ep. 29
00:00 Intro 01:15 From your perspective, why is cellular therapy an important topic for our listeners? 02:55 What is your origin story into this world of cellular therapy? 06:20 Working in such a fast-paced area, what has been a unique challenge you have had to navigate and how have you done that? 08:05 Keeping up with the literature can be a challenge, and once you are out of training you don’t have those deadlines of “have you read your recent articles for the month.” How have you approached k...
Feb 05, 2021•16 min•Ep. 28
Timestamps: 00:00 Intro 00:58 How is cellular therapy contributing to the COVID effort? 04:42 Can you give us a little bit of an introduction about what’s so important about the cell (mesenchymal stem cell) or where it comes from? 08:19 What sort of work are you and your lab doing for patient care? 11:14 Once you figure out a successful cellular therapy, is there then opportunity for that to get brought to scale for a given patient population, or does cellular therapy need to exist as a very ind...
Jan 22, 2021•17 min•Ep. 27
00:00 Intro 00:45 Can you let our listeners know what we know about the vaccines at this point (December 2020)? 02:00 With using the mRNA approach, do these vaccines have similar performance characteristics? 03:00 What does this mean for people after they get vaccinated? Hearing this high numbers of efficacy that is protecting me from the virus, what does this mean for how I should be behaving after I get vaccinated? 04:25 What are your thoughts on if there should be post-vaccination serology te...
Jan 08, 2021•12 min•Ep. 26
Timestamps: 00:00 Intro 01:00 As Pathologists, we have a lot of competing priorities. Why is mentoring residents and fellows consistently a high priority for you? 03:27 Often what we are trying to do as educators is not transparent to our learners, for a variety of reasons. What do you wish that all residents, fellows, and learners understood about the process of their training? 05:00 How do you address someone who started out on the right food and then started a slip a little and stopped taking...
Dec 04, 2020•12 min•Ep. 25
Timestamps: 00:00 Intro 01:00 What is HIT and why is it important for clinicians to correctly diagnose HIT? 03:30 What do we know about how laboratory testing may help clinicians get the diagnosis right? 07:25 How could the process of diagnosing HIT be updated or made better? 10:45 What does the future hold for HIT testing? In five years’ time what do you think HIT testing is going to look like in this country? 12:45 How has your relationship with your clinical colleagues helped advance your pra...
Nov 13, 2020•16 min•Ep. 24
Timestamps: 00:00 Intro 01:00 Why is it important for medical students to prepare for their residency interviews? 3:00 What do recommend that students do to prepare for those interviews? Is it looking at websites online or going to PubMed? 05:35 Assuming many interviews will be virtual, is it fair game for an applicant to reach out to the program interviewers ahead of time to ask them if they can test out the system if they are unfamiliar with it? 08:45 Do you have any thoughts on how students c...
Nov 06, 2020•26 min•Ep. 23
Time Stamps 00:00 Podcast Intro 00:35 Now that the EAP is closed, how are doctors getting convalescent plasma for their patients? 08:50 What new information have we learned about convalescent plasma in recent months? 13:28 If we are in a period of shortage and there is only low titer available, is it ideal to transfer two units of convalescent plasma in that context? 15:30 What remaining questions about convalescent plasma are you most curious about? 18:52 How can study design enable or inhibit ...
Oct 02, 2020•25 min•Ep. 22
Time Stamps 00:00 Podcast Intro 00:40 Why is it important for a laboratory to detect or quantify opioids? 02:00 What are the challenges you have had to navigate in the laboratory specific to opioids? 04:47 Is it like a pregnancy test or is it important to quantify as well? 05:19 Can you help us understand how you collaborate with other health care professionals? 07:07 In terms of new or illicit street drugs, are you having to constantly design new tests to detect these things? 07:53 Can you elab...
Sep 11, 2020•13 min•Ep. 21
Timestamps 00:00 Podcast Intro 00:45 Why is it important for laboratory medicine and pathology to be deliberate about diversity and inclusion? 03:11 How do you recommend we transform the question “will they fit?” or “do I fit?” so that it invites diversity? 05:33 So, it’s not so much of transforming the question but putting it ahead of the interview and thinking about what you are trying to recruit for? 06:22 What information have we recently learned about diversity and inclusion in the newer fi...
Aug 21, 2020•17 min•Ep. 20
Time Stamps 00:00 Podcast Intro 00:50 Why does this landscape of COVID testing seem so dynamic? 03:47 So it sounds like we have two sort of rapid tests that are on the market now. Can we dive into that so that we can appreciate a little bit of the compare and contrast between those two rapid assays? 07:17 What are these unique challenges with regards to sensitivity and specificity when it comes to these rapidly evolving tests? 11:08 Highlighting the connection between laboratory medicine and the...
Aug 07, 2020•20 min•Ep. 19
Time Stamps 00:00 Podcast Intro 00:51 This is a nice time of year for the academic calendar with new trainees starting residency, and new faculty starting their jobs, and people still in their first couple of years of being an academic pathologist. Why is it important for these individuals to be deliberate about how they begin their career? 04:18 When somebody is in training, there is a lot that is decided for them and things are predetermined. In residency that opens up quite a bit. Can you giv...
Jul 24, 2020•29 min•Ep. 18
Time Stamps 00:00 Podcast Intro 01:05 Why is it important to explain the laboratory to patients? How important it is to have open/honest communication with patients? 07:05 With your experience in talking with children and their families is your focus on the child and the parents picks up on your efforts? Or are you addressing the child separately from their parents? 11:10 What tips would you have for pathologists as they approach certain situations (approaching the bedside, engaging with patient...
Jul 01, 2020•35 min•Ep. 17
00:00 Podcast Intro 00:53 There seems to be a lot of buzz around the need for interprofessional education and interprofessional collaboration. Can you kind of take us through these concepts? How are they the same, or how are they different? 02:37 What’s the why here? Why should health care institutions, us as individuals, why should we prioritize this interprofessional education or collaboration in practice? 05:34 I imagine there are a lot of people listening who have meetings…for example we hav...
Jun 05, 2020•23 min•Ep. 16
Time Stamps 00:00 Podcast Intro 03:19 How did you choose forensic pathology as a career? 04:30 Where did you train and where were you prior to Mayo? 05:08 Can you discuss in general the practice of forensic pathology, and the difference between hospital and medicolegal autopsies? 06:37 How often do forensic pathology and microbiology intersect? 07:57 What are the challenges of performing microbiology studies in your practice? 08:54 What types of interesting microbiology cases have you seen so fa...
May 27, 2020•26 min•Ep. 3
Time Stamps 00:00 Podcast Intro 00:40 What is COVID-associated coagulopathy and why is it important to recognize this? 02:45 How is this coagulopathy similar to or different from other coagulopathies that we commonly see in clinical practice? 04:30 Is there recommended testing for COVID-associated coagulopathy? 06:30 Can you explain what the soluble fibrin monomer test is? 08:09 How is COVID-associated coagulopathy managed in terms on prophylactic anticoagulation, therapeutic anticoagulation, an...
May 06, 2020•18 min
Time Stamps 00:00 Podcast Intro 00:39 What is they ‘why’ behind starting up a convalescent plasma program? 04:00 If physicians are taking care of a patient and wanting to get this product how do they go about it? 11:23 With the Expanded Access Protocol and Emergency IND, how many products does that get for the given patient? 13:00 Where should we direct people who are interested in being a donor? 14:51 Can you give us an idea on who would be eligible to donate convalescent plasma? 17:16 What are...
May 01, 2020•24 min•Ep. 15
00:00 Podcast Intro 00:56 On a lot of T.V. shows that I’ve watched over the years, I see the surgeons and emergency medicine docs after they see the patient pop back in the lab and perform those critical tests. In reality, is that really what’s going on? 01:42 Myself as a pathologist, I understand for a lot of physicians I’m probably one degree removed from the bedside, so one degree outside of their mind, and maybe the medical technologist is another degree. So for our physicians and clinicians...
Apr 20, 2020•26 min•Ep. 14
