High risk factors for stroke such as smoking and blood pressure are not equally represented throughout the patient population. These are just two of the socioeconomic influences on cerebrovascular disease. One way to view this association is through the lens of the Area Deprivation Index (ADI), a measure of neighbourhood-level deprivation, and this was the approach of the study discussed in this episode. The study evaluated the association between the ADI and the treatment of ruptured intracrani...
May 29, 2025•13 min•Ep. 96
The "River" stent is a novel stent designed specifically to account for the anatomical and procedural requirements of venous sinus stenosis. A multicentre study of the device's safety and efficacy is underway, comprising 39 subjects across 5 US centres. The 1-year results have been recently published in JNIS. Editor-in-Chief of JNIS, Dr. Felipe C. Albuquerque, interviews Dr. Athos Patsalides¹, author of the paper: The River study: the first prospective multicenter trial of a novel venous sinus s...
Apr 23, 2025•18 min•Ep. 95
Observations from practice and data analysis have shown that the duration of mechanical thrombectomy procedures are a strong predictor of outcome even with successful procedures. A large multicenter study was conducted which gives insight into choices between catheter types, and strategic decisions to be made during prolonged procedures. Dr Felipe C. Albuquerque, Editor-in-Chief of JNIS, interviews Dr. Ali Alawieh¹ and Dr. Alejandro Spiotta², two authors of the paper: Prolonged intracranial cath...
Feb 14, 2025•22 min•Ep. 94
The use of assistive devices when treating unruptured aneurysms is widespread in neurointerventional practice. But there is no standard for how long patients should receive dual anti-platelet therapy after the procedure, to protect them from thrombotic complications. Durations can range from one month to one year. This episode looks at a review of patient data across 12 locations to understand the effect of therapy duration on risk of complications. Dr Felipe C. Albuquerque, Editor-in-Chief of J...
Jan 07, 2025•16 min•Ep. 93
There has been a large increase in the number of non-invasive neurovascular studies performed in the last decade, particularly CT angiograms and MR angiograms. What has this meant for catheter-based angiography? This episode looks at an analysis done on a large claims database in the USA, to observe trends in imaging modalities, as well as the distinctions in use by neurosurgeons and radiologists. Dr Felipe C. Albuquerque, Editor-in-Chief of JNIS, interviews Dr. Francis Jareczek¹ and Dr. D. Andr...
Dec 12, 2024•17 min•Ep. 92
Although many U.S. neurointerventionalists report at least one stressful malpractice claim over their career, the majority conclude without any court proceedings or direct repercussions in their practice. In this podcast, we look at the prevalence and causes of malpractice claims and complaints filed with state medical boards against neurointerventionalists, and some of the risk factors in an increasingly busier field. Dr Felipe C. Albuquerque, Editor-in-Chief of JNIS, interviews Dr Kyle M. Farg...
Oct 04, 2024•22 min•Ep. 91
Single-stent assisted coiling techniques such as ‘L-stenting’ are an alternative to intrasaccular devices for wide-neck bifurcation aneurysms. In this episode, Aliya Siddiqui¹ and Dr. Reade De Leacy² join JNIS editor-in-chief Dr. Felipe Albuquerque to discuss the background and findings of their recent study, regarding the efficacy and safety of the 'L-stenting' technique. Read the paper: A core-lab adjudicated analysis of single-stent assisted coiling of wide-neck bifurcation aneurysms 1. Medic...
Jul 04, 2024•20 min•Ep. 90
Patients with good motor function outcomes after aneurysmal subarachnoid hemorrhage treatment may still be left with neuropsychiatric effects. They can suffer from such difficult conditions as cognitive dysfunction, depression and sexual dysfunction. Not all of these patients will volunteer their symptoms unprompted on follow-up. This outcome type has had limited study, and became an interest of today's guest, Dr. Jose Danilo Bengzon Diestro (1). JNIS editor-in-chief Dr. Felipe Albuquerque speak...
May 07, 2024•18 min•Ep. 89
Alis Dicpinigaitis (1) and Dr. Fawaz Al-Mufti (2) join JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, to discuss the study, "Mapping geographic disparities in treatment and clinical outcomes of high-grade aneurysmal subarachnoid hemorrhage in the United States". They explain the findings of their study, covering the predictive impact of factors including age, insurance status, race, and hospital ownership. Read the paper: https://jnis.bmj.com/content/early/2024/02/19/jnis-2023-021330 (1) New Y...
Apr 05, 2024•19 min•Ep. 88
Dr. Michael Veldeman (1) joins JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, to discuss the study, "Intra-arterial nimodipine for the treatment of refractory delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage". Dr. Veldeman explains the methods of the study, the growing significance of computerised tomography perfusion imaging in diagnosis of unconscious patients, the use of induced hypertension, and interventional complications that arose when treating subarachnoid hemorrhage...
Feb 13, 2024•18 min•Ep. 87
JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, is joined from New York by Prof. David Fiorella (1) to discuss the paper, "Safety and effectiveness of the Woven EndoBridge (WEB) system for the treatment of wide necked bifurcation aneurysms: final 5 year results of the pivotal WEB Intra-saccular Therapy study (WEB-IT)". Prof. Fiorella explains the results of this extensive study across 27 locations, with the WEB device proving to be a durably effective and safe endovascular treatment option for ...
Dec 13, 2023•20 min•Ep. 86
JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, is joined from Calgary by Dr. Johanna Ospel (1) to discuss "Recent developments in pre-hospital and in-hospital triage for endovascular stroke treatment", a paper detailing the many aspects of resource allocation when treating stroke patients. Read the paper: https://jnis.bmj.com/content/early/2022/10/14/jnis-2021-018547 (1) Departments of Radiology and Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada Please subscribe to the...
Oct 05, 2023•24 min•Ep. 85
In this podcast, JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, speaks with Dr. Michael Levitt (1) and Dr. Colin Derdeyn (2), authors of a pair of editorials discussing the practice of dural venous sinus stenting for patients with idiopathic intracranial hypertension. Point: Dural venous sinus stenting should be considered a first-line treatment option for select patients with idiopathic intracranial hypertension https://jnis.bmj.com/content/early/2023/06/20/jnis-2023-020597 Counterpoint: sten...
Aug 16, 2023•32 min•Ep. 84
In this podcast, JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, speaks with Dr. Marco Colasurdo (1) and Prof. Dheeraj Gandhi (2), authors of the original research article, "Predictors for large vessel recanalization before stroke thrombectomy: the HALT score" - https://jnis.bmj.com/content/early/2023/04/25/jnis-2023-020220 This paper is free-to-access for a month following the publication of this podcast. Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts,...
May 26, 2023•18 min•Ep. 83
In this podcast, JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, speaks with Mariam Kyarunts(1) and Charlotte Michaelcheck(2), contributing authors to the recently published article "Gender disparities in industry compensation and research payments among neurointerventional surgeons in the USA" - https://jnis.bmj.com/content/early/2023/01/23/jnis-2022-019921 This paper is free-to-access for a month following the publication of this podcast. Please subscribe to the JNIS Podcast via all podcast p...
Mar 29, 2023•16 min•Ep. 82
In this podcast, JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, speaks with Dr. Kyle Fargen(1) about the recently published study "Mechanical thrombectomy decision making and prognostication: Stroke treatment Assessments prior to Thrombectomy In Neurointervention (SATIN) study" - https://jnis.bmj.com/content/early/2023/01/05/jnis-2022-019741.long Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest ep...
Feb 08, 2023•28 min•Ep. 81
In this podcast, JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, speaks with Dr. Amanda Baker(1) and Dr. Sandra Narayanan(2) about their recently published standard "Society of NeuroInterventional Surgery: position statement on pregnancy and parental leave for physicians practicing neurointerventional surgery" - https://jnis.bmj.com/content/15/1/5. Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest e...
Jan 05, 2023•21 min•Ep. 80
In this podcast, JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, speaks with Dr. Krishna C. Joshi(1) and Dr. Michael Chen(2) about their paper "Endovascular thrombectomy for acute ischemic stroke in patients with cancer: a propensity-matched analysis" - https://jnis.bmj.com/content/14/12/1161. Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a ...
Dec 20, 2022•17 min•Ep. 79
In this podcast, JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, speaks with Dr. Matthew Amans(1) and Daniel Cummins(2) about their paper "Cerebrovascular pulsatile tinnitus: causes, treatments, and outcomes in 164 patients with neuroangiographic correlation" - https://jnis.bmj.com/content/early/2022/09/08/jnis-2022-019259. Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please con...
Oct 31, 2022•30 min•Ep. 78
The 2013 ARUBA trial concluded that medical management alone is superior to medical management with interventional therapy for patients with unruptured brain arteriovenous malformations. A study was conducted to analyze AVM treatment and epidemiologic response to the ARUBA trial. Following ARUBA, there has been a stark decrease in interventions for uAVMs. Nationwide rAVM discharge incidence is inversely correlated with uAVM intervention rate. Less uAVM interventions may lead to a substantial inc...
Sep 07, 2022•21 min•Ep. 77
Survival for glioblastoma remains very poor despite decades of research, with a 5-year survival of only 5%. Technological improvements that have revolutionized treatment of ischemic stroke and brain aneurysms have great potential in providing more precise and selective delivery of cancer therapeutic agents to brain tumors. In this podcast, JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque speaks with Dr. Stephen Chen (1)and Dr. Peter Kan (2) about their paper "Perfusion-guided endovascular super-s...
Jun 27, 2022•23 min•Ep. 76
The Woven EndoBridge (WEB) device has FDA approval for treatment of wide-necked intracranial bifurcation aneurysms. It has been shown to result in adequate occlusion in bifurcation aneurysms overall, but its usefulness in the individual bifurcation locations has been evaluated separately only in few case series, which were limited by small sample sizes. In this podcast, JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, interviews Dr. Nimer Adeeb (1)and Dr. Adam Dmytriw (2) on their paper "Compari...
May 17, 2022•26 min•Ep. 75
Sex disparities in acute ischemic stroke outcomes are well reported with IV thrombolysis. Despite several studies, there is still a lack of consensus on whether endovascular thrombectomy (EVT) outcomes differ between men and women. In this podcast, we discuss the Selection for Endovascular Treatment in Acute Ischemic Stroke (SELECT) study, in which women had similar discharge outcomes as men following EVT, in a propensity-matched cohort, but the improvement from discharge to 90 days was signific...
Apr 12, 2022•26 min•Ep. 74
In the latest podcast, we discuss the joint expedited recommendations from the European Stroke Organisation (ESO) and the European Society for Minimally Invasive Neurological Therapy (ESMINT) on indication for intravenous thrombolysis before mechanical thrombectomy in patients with acute ischemic stroke and anterior circulation large vessel occlusion. JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, interviews Dr. Guillaume Turc, Department of Neurology, GHU Paris Psychiatrie et Neurosciences, U...
Feb 15, 2022•24 min•Ep. 73
Venous sinus stenting (VSS) is a safe, effective, and increasingly popular treatment option for selected patients with idiopathic intracranial hypertension (IIH). Serious complications associated with VSS are rarely reported. In this podcast, JNIS Editor-in-Chief, Felipe C. Albuquerque, interviews Dr. Kyle Fargen, from the Department of Neurosurgery, Wake Forest University, Winston-Salem, North Carolina, about a case series in which serious complications after VSS were identified retrospectively...
Dec 13, 2021•22 min•Ep. 72
In this podcast, we discuss the COMPASS: a trial of aspiration thrombectomy versus stent retriever thrombectomy as first-line approach for large vessel occlusion, comparing patients with and without prior intravenous (IV) alteplase administration. JNIS Editor-in-Chief, Felipe C. Albuquerque, interviews Maxim Mokin, from the Department of Neurosurgery and Brain Repair, University of South Florida, Tampa, USA, about the post hoc analysis. which concludes that prior administration of IV alteplase m...
Nov 17, 2021•17 min•Ep. 71
Flow diversion of intracranial aneurysms with the Pipeline Embolization Device (PED) is commonly performed, but the value of long-term angiographic follow-up has not been rigorously evaluated. The study discussed in this podcast examines the prevalence of actionable findings of aneurysm recurrence and development of in-stent stenosis in a cohort of patients that underwent long-term angiographic follow-up at multiple time points. JNIS Editor-In-Chief, Felipe C. Albuquerque, interviews Dr Akash P....
Aug 19, 2021•16 min•Ep. 70
Retinoblastoma is the most common primary intraocular malignancy in children. In this podcast, JNIS Editor-In-Chief Felipe C. Albuquerque and Pascal Jabbour discuss a study from July’s issue, concluding that local factors relating to the chemotherapy and selective microcatheterization of the ophthalmic artery are essential factors in the development of ophthalmic artery thrombosis, as seen by the association of ophthalmic artery thrombosis with the frequency of intra-arterial chemotherapy. Dr Ja...
Jun 25, 2021•19 min•Ep. 69
In this podcast, JNIS Editor-In-Chief Felipe C. Albuquerque and Adnan Siddiqui discuss a case series that describes complete flow control using concurrent transient rapid ventricular pacing with afferent arterial balloon flow arrest technique as “safe and feasible” for transvenous embolization of select cerebral arteriovenous malformations (AVM). Dr Siddiqui (Department of Neurosurgery, University at Buffalo, NY, USA) is the lead author of “Complete flow control using transient concurrent rapid ...
Apr 01, 2021•23 min•Ep. 68
JNIS Editor-In-Chief, Felipe C. Albuquerque, interviews Sami Al Kasab and Alejandro Spiotta, both from the Medical University of South Carolina, Charleston, USA. They discuss the Stroke Thrombectomy and Aneurysm Registry data showing an “alarming downtrend in mechanical thrombectomy rates in African American patients during the COVID-19 pandemic”. Read the related article online (https://jnis.bmj.com/content/early/2021/01/06/neurintsurg-2020-016946) and in the March issue of JNIS. Please subscri...
Feb 15, 2021•22 min•Ep. 67