JACC Specialty Journals - podcast cover

JACC Specialty Journals

American College of Cardiologywww.jacc.org
In this podcast series, editors-in-chief from the JACC family of specialty journals provide highlights and summarize key findings for select issues. Published by the American College of Cardiology, the JACC Journals publish peer-reviewed articles on all aspects of cardiovascular disease, including original clinical studies, translational investigations with clear clinical relevance, state-of-the art papers, and review articles. They are top ranked for impact factor and their manuscripts are among the most covered by media outlets, most talked about on social media, and most read online.
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Episodes

JACC: CardioOncology Pulse - Cardio-Oncology in Japan

Sivatharshini Ramalingam, MD, Kazuhiro Sase, MD, PhD and Yugo Yamashita, MD, PhD, discuss evolving cardio-oncology in Japan, focusing on new guidelines, interdisciplinary care, and cancer-related cardiovascular risks.

Oct 22, 202427 min

JACC: CardioOncology - October 2024 Issue Summary

This issue features the first ever JACC: CardioOncology Expert Panel, providing consensus guidance and identifying the gaps in evidence in the cardiovascular care of our cancer patients. This is the first of a 3-part series focused on advancing evidence-based cardiovascular care prior to, during and after cancer therapy. Additionally, in this issue, we feature a number of high-impact state of the reviews, original research manuscripts and viewpoints.

Oct 15, 202424 min

JACC: CardioOncology - Use of Polygenic Risk Score for Prediction of Heart Failure in Cancer Survivors

In this episode, Dr. Sonia Shah explores a study from Australian researchers that evaluates the effectiveness of a polygenic risk score in predicting heart failure among cancer survivors. While the score enhanced prediction compared to age and sex alone, it did not significantly outperform existing modifiable risk factors, highlighting the need for more comprehensive models that account for unique risks faced by cancer patients.

Oct 15, 20243 min

JACC: CardioOncology - Autonomic Dysfunction Among Adult Survivors of Childhood Cancer in the St. Jude Lifetime Cohort Study

In this episode, Efstratios Koutroumpakis discusses a critical study on autonomic dysfunction among adult survivors of childhood cancer, highlighting its prevalence and functional significance compared to community controls. The research underscores the complex etiologies of autonomic dysfunction linked to cancer treatments and stresses the importance of early detection and standardized testing to improve cardiovascular health and quality of life in this growing survivor population.

Oct 15, 20245 min

JACC: CardioOncology - Life's Essential 8 and Incident Cardiovascular Disease in US Women with Breast Cancer

In this episode, Dr. Tochi Okwuosa discusses a pivotal study examining the association between the Life Essential 8 cardiovascular health score and the incidence of cardiovascular disease in women with breast cancer. The research, which followed over 7,000 participants, found that higher scores correlated with significantly lower rates of cardiovascular events, underscoring the importance of cardiovascular health even in cancer patients and highlighting the need for future studies in more divers...

Oct 15, 20243 min

JACC: CardioOncology - Adiposity and Muscle Strength in Men with Prostate Cancer and Cardiovascular Outcomes

In this episode, Dr. Josh Mitchell reviews a significant study that explores the links between physical health markers, such as waist circumference and hand grip strength, and cardiovascular outcomes in men with prostate cancer undergoing androgen deprivation therapy. The findings indicate that increased waist circumference and decreased grip strength are associated with higher cardiovascular event risks, highlighting the need for targeted interventions like exercise in these patients and emphas...

Oct 15, 20243 min

JACC: CardioOncology - Multi-Cohort Epigenome-Wide Association Study of All-Cause Cardiovascular Disease and Cancer Incidence: A Cardio-Oncology Approach

In this episode, Brian Joyce discusses a groundbreaking study that examines the link between DNA methylation and the incidence of cardiovascular disease and cancer across three major cohorts. The research identifies shared epigenetic signatures associated with both diseases, highlighting the need for further investigation into their functional implications and potential clinical applications in diverse populations.

Oct 15, 20242 min

JACC: CardioOncology - Prognosis after Withdrawal of Cardioprotective Therapy in Patients with Improved Cancer Therapeutics-Related Cardiac Dysfunction

In this episode, Brian Halliday discusses a Korean study examining the outcomes of patients with cancer therapeutics-related cardiac dysfunction after withdrawing cardioprotective therapy. He highlights that while patients with an ejection fraction between 45 and 55% fared similarly regardless of therapy continuation, those with an ejection fraction below 45% experienced worse outcomes when they withdrew treatment, underscoring the need for further randomized trials to refine therapeutic approac...

Oct 15, 20243 min

JACC: CardioOncology - Preventing Cardiac Damage In Patients Treated For Breast Cancer And Lymphoma: The PROACT Clinical Trial

In this episode of the JACC: CardioOncology Podcast, Antonio Cannata discusses the PROACT clinical trial, which investigated the effectiveness of enalapril in preventing cardiac damage in breast cancer and lymphoma patients undergoing anthracycline therapy. Despite neutral results, the conversation delves into the challenges of defining myocardial injury and emphasizes the need for improved risk stratification and innovative trial designs in future research.

Oct 15, 20243 min
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