Cardiovascular Protection Beyond Statins--Nattokinase, Vitamin K2 MK-7, and Clinical Cardio Six: Neil Levin of NOW Foods/ Protocol for Life Balance details cardiovascular protection beyond cholesterol-lowering drugs, emphasizing nutrient sufficiency, therapeutic “nutraceutical” dosing, and physician partnership with testing. They discuss nattokinase from fermented natto (typical 2,000 fibrinolytic units/day), describing research on reduced fibrinogen, improved blood viscosity and microcirculatio...
Jul 01, 2026•33 min
Dr. Hoffman continues his conversation with Neil Levin, the Senior Nutrition Education Manager and a product formulator for NOW(r) Foods and Protocol for Life Balance .
Jul 01, 2026•40 min
Urolithin A (Mitopure) and Mitochondrial Renewal--Muscle, Immune, and Skin Benefits: Jen Scheinman, MS, RDN, CDN, Director of Science Communications at Timeline details urolithin A and Timeline’s branded supplement Mitopure. She describes urolithin A’s discovery through pomegranate research and worm studies showing a 45% lifespan increase. She discusses human research including improved walking distance and clinical outcomes in muscle endurance and strength. Urolithin A is presented as supportin...
Jun 30, 2026•27 min
Dr. Hoffman continues his conversation with Jen Scheinman, MS, RDN, CDN, Director of Science Communications at Timeline .
Jun 30, 2026•29 min
“The quick and the dead”: 80+ “Supermovers” show slowed cognitive decline; Dietary polyphenols help overcome vascular effects of prolonged sitting; Pros and cons of ketamine therapy for depression; Time-restricted eating alters microbiome to promote weight loss; Magnesium—what research reveals about better sleep, stress resilience, and whole-body wellness.
Jun 29, 2026•36 min
CBD may slow Alzheimer’s progression by tamping down brain inflammation; Fifty million dollar settlement in Gardasil Classic action; Urethral stricture as a side effect of ablation for enlarged prostate; Zero-sugar diet may have unanticipated adverse health consequences; Are there drug-free alternatives for atrial fibrillation? Can you reverse lactose intolerance with a skin patch?
Jun 29, 2026•35 min
Vitamin K2 (MK-7) and Coronary Artery Calcification: Insights from a 2-Year Trial: Nutritionist Leyla Muedin discusses a two-year randomized clinical trial in JAMA Cardiology from Maastricht University Medical Center reporting that daily vitamin K2 (menaquinone-7, MK-7) at 360 mcg slowed progression of coronary artery calcification (CAC) in 180 patients with confirmed atherosclerotic cardiovascular disease and baseline CAC 50–400 Agatston units. Compared with placebo, consistent MK-7 use was ass...
Jun 26, 2026•22 min
World Cup! What did humans eat from the Ice Age to the Bronze Age? What supplements should I avoid while undergoing radiation therapy for prostate cancer? What is the treatment for sarcoidosis of the lung? Both my friend and his wife have it.
Jun 25, 2026•32 min
I'm 78 and had a hysterectomy. Is it safe for me to eat tofu or other soy foods? Mitopure joins L'Oreal to create a face cream with Urolithin A. Does taking hyaluronic acid orally cause water retention? Can you discuss ETA contained in New Zealand green mussels? What are your thoughts on using vibration devices to help osteoporosis?
Jun 25, 2026•33 min
Nathan Jones, founder and CEO of Xlear, Inc. , reveals xylitol’s role in supporting oral and nasal “gateway” microbiomes by selectively starving acid-producing Strep mutans rather than indiscriminately killing bacteria, and warns that harsh mouthwashes can disrupt beneficial oral bacteria linked to nitric oxide production and possibly blood pressure. Jones outlines Spry and Xlear products (gum, mints, toothpaste, mouthwash, dry-mouth “Rain,” and upcoming gummy candies, a new dental probiotic wit...
Jun 24, 2026•26 min
Dr. Hoffman continues his conversation with Nathan Jones, founder and CEO of Xlear, Inc.
Jun 24, 2026•31 min
Nitric Oxide Explained: Vascular Health, Exercise Performance, and N1o1 with Dr. Nathan Bryan , international Leader in Molecular Medicine, the first to describe nitrite and nitrate as indispensable nutrients required for optimal cardiovascular health. He details NO as a ubiquitous messenger affecting blood flow, erectile function, cognition, exercise performance, endothelial dysfunction, and aging-related declines in NO production. Bryan explains why PDE5 inhibitors like Viagra prolong cyclic G...
Jun 23, 2026•25 min
Dr. Hoffman continues his conversation with Dr. Nathan Bryan , international Leader in Molecular Medicine, the first to describe nitrite and nitrate as indispensable nutrients required for optimal cardiovascular health.
Jun 23, 2026•39 min
Should you stop taking glucosamine based on a new study linking it to Alzheimer’s? What’s behind the spate of “Tai Chi Walking” social media posts? Undereye “festoons”—what to do about them? Are antibiotics the only treatment for SIBO? Vaping after smoking hikes risk for lung cancer.
Jun 22, 2026•36 min
Why aren’t there more medical insurance plans that cover alternative medicine? Solutions for Long Covid; MK7 vitamin K slows arterial calcification; Keto diet shows promise for treatment of anorexia; It’s not so much salt restriction—it’s the dietary sodium/potassium ratio in hypertension; Study finds multivitamins don’t keep you from getting Covid—but when you get it, it’s milder; Incidence of social anxiety disorder is soaring among young people.
Jun 22, 2026•36 min
Sleep, Glymphatic Detox, and the Hidden Heart Risks of Sleep Apnea: Nutritionist Leyla Muedin explains how sleep supports brain “housekeeping” via the glymphatic system, a glial-lymphatic waste-clearance network most active during sleep that moves cerebrospinal fluid through brain spaces to remove metabolites and toxic proteins such as amyloid beta, with sleep deprivation linked to amyloid accumulation. She notes other clearance pathways, including meningeal lymphatic vessels, whose impaired fun...
Jun 19, 2026•22 min
Is there any truth to some of the latest news that claims glucosamine supplements accelerate dementia and Alzheimer's? Some key points on methodology - what were they actually measuring? What does glucosamine have to do with hyperglycosylation?
Jun 18, 2026•37 min
What may be the real driver of persistent musculoskeletal pain in menopause? What are your thoughts on hyperbaric oxygen for treating hard-to-heal wounds? Kudos to holistic veterinarians! My prostate is Swiss cheese now after so many biopsies What's the latest on melatonin?
Jun 18, 2026•27 min
In this episode of the Intelligent Medicine podcast, Dr. Ronald Hoffman interviews Professor Kieran Murphy, an interventional neuro radiologist and prolific inventor from Toronto Western Hospital. Dr. Murphy has developed numerous innovative medical devices and filed 60 patents. He shares insights from his book, “ The Essence of Invention: Medicine and the Joy of Creativity ,” discussing his work on medical innovation, his unique background, and personal experiences that have driven his creative...
Jun 17, 2026•27 min
Dr. Hoffman continues his conversation with Dr. Kieran Murphy, author of “ The Essence of Invention: Medicine and the Joy of Creativity ,”
Jun 17, 2026•38 min
Pandemic Policies, Vaccines, and Harms to Children: pediatrician and author Dr. Elizabeth Mumper discusses her book “ Kids and COVID: Costly Mistakes That Must Never Happen Again .” Mumper argues parents should question authorities, citing early pandemic decisions such as lockdowns, masking, and a “one size fits all” vaccine strategy despite children’s low risk from COVID. She supports the Great Barrington Declaration’s focus on protecting high-risk groups and criticizes suppression of repurpose...
Jun 16, 2026•30 min
Dr. Hoffman continues his conversation with pediatrician and author Dr. Elizabeth Mumper.
Jun 16, 2026•35 min
Want a suitcase of antibiotics? Online “wellness” companies will oblige, but the disruption to your microbiome may last up to 8 years; What’s the best form of curcumin? New push to promote nutrition instruction for doctors—is it enough? “Borderline anemia”—what could be the cause?
Jun 15, 2026•35 min
More than just a game—Knicks overcoming odds in game 4 comeback is a parable of resilience; A one and done lifetime cholesterol fix via gene modification; Will cataract surgery interfere with benefits of light exposure? Do amounts of vitamin A in various supplements taken together court the risk of toxicity? Smartphones and social media create real harm for adolescents; Experts determine the exact right amount of sleep down to the minute—but is it overreach?
Jun 15, 2026•35 min
Perimenopause, Insulin Resistance, and Persistent Muscle & Joint Pain: A Functional Medicine Framework: Nutritionist Leyla Muedin discusses perimenopausal musculoskeletal symptoms—new or persistent joint pain, muscle aches, and tendon problems—and highlights a Clinician’s Journal article by physical therapist Tara Moore proposing insulin resistance screening in perimenopausal musculoskeletal care. She explains that declining estradiol during the menopausal transition can worsen insulin signa...
Jun 12, 2026•21 min
Deprescribing thyroid and other meds in older adults Can I safely take serrapeptase for longer than four weeks? I want to take nattokinase but isn't there a 'clot dislodging' risk? Could you discuss C. difficile and how to treat it?
Jun 11, 2026•33 min
I do stair climbing indoors in bad weather instead of walking outdoors. Is this worthwhile? The FDA no longer recommends use of radiation shields during X-ray procedures. What say you? I have a queasy stomach feeling, and my blood sugar is higher than usual. What are your thoughts? I've been using magnesium taurate to control palpitations and find I need more than usual. A comment about performance-enhancing drugs in professional sports
Jun 11, 2026•30 min
Comprehensive Insights into Bioidentical Hormone Replacement Therapy with Dr. Erika Schwartz, author of “ The New Hormone Solution .” In this episode of the Intelligent Medicine Podcast, Dr. Ronald Hoffman speaks with Dr. Erika Schwartz, an expert in bioidentical hormone replacement therapy. They discuss the evolution and controversies surrounding hormone therapies, including the impact of the Women's Health Initiative study. Dr. Schwartz shares her insights on the importance of a tailored appro...
Jun 10, 2026•30 min
Dr. Hoffman continues his conversation with Dr. Erika Schwartz, author of “ The New Hormone Solution .”
Jun 10, 2026•30 min
Dr. Garth Nicolson, Founder, President, Chief Scientific Officer, and Emeritus Research Professor of Molecular Pathology at the Institute for Molecular Medicine in Huntington Beach, California, and Research Advisor for Nutritional Therapeutics , explains how membrane damage from free radicals and loss of mitochondrial transmembrane potential contribute to declining energy with age, noting studies in older adults showing improved energy output, fatigue, cognition, mood, and activity after NTFacto...
Jun 09, 2026•25 min
