Dr. Garth Nicolson, Founder, President, Chief Scientific Officer, and Emeritus Research Professor of Molecular Pathology at the Institute for Molecular Medicine in Huntington Beach, California, and Research Advisor for Nutritional Therapeutics , explains how membrane damage from free radicals and loss of mitochondrial transmembrane potential contribute to declining energy with age, noting studies in older adults showing improved energy output, fatigue, cognition, mood, and activity after NTFacto...
Jun 09, 2026•27 min
Dr. Hoffman continues his conversation with Dr. Garth Nicolson, Founder, President, Chief Scientific Officer, and Emeritus Research Professor of Molecular Pathology at the Institute for Molecular Medicine in Huntington Beach, California, and Research Advisor for Nutritional Therapeutics .
Jun 09, 2026•42 min
The “Enhanced Games”, with no-holds-barred performance-enhancing drugs, yields scant advantages over “clean” contests; Does saturated fat increase insulin resistance? Can a heart attack victim avoid statin use with CoQ10? Omega-3 fish oil shows promise vs. type 2 diabetes; Motorized e-scooter use needs to be regulated NOW!
Jun 08, 2026•43 min
AI founders call for Congress to set guardrails against AI-accelerated bioweapon development; Deprescribing thyroid medication in seniors; Low-arginine/high lysine diets vs. herpes; Researchers test the “5 second rule” for dropped food; Long-term antidepressant use comes under new scrutiny.
Jun 08, 2026•45 min
Nutritionist Leyla Muedin discusses research showing simple strength tests—grip strength and a five-rep sit-to-stand chair test—predict longevity in older women. In a University at Buffalo study of over 5,000 women ages 63–99 followed for eight years, stronger grip and faster chair-stand times were linked to lower mortality; every additional 7 kg of grip strength corresponded to a 12% reduction in death risk, and faster chair-stands were also associated with improved survival, even after adjusti...
Jun 05, 2026•24 min
Can topical B12 help relieve itching? The types of doctors to avoid Getting back to basics A case study of lavender oil helping to relieve itching You say you're dairy sensitive but you use whey protein. Please explain. What are your thoughts on a lactose relief patch that is on offer?
Jun 04, 2026•35 min
Is high blood pressure genetic? Are we stuck having to take blood pressure meds? Could you please critique the study asserting fish oil supplements elevate the risk of atrial fibrillation? I've had strep throat three times in two months! What gives? I've had queasy reactions to protein added foods
Jun 04, 2026•35 min
A Brand New Tool for Gut, Inflammation, and Brain Support: Holistic Practitioner Jane Jansen details Essential Formulas’ Dr. Ohhira’s Postbiotic Fermented Food Concentrate , a non-GMO, gluten-free, dairy-free, capsule-free fermented paste in travel-friendly, non-refrigerated sachet packets. She explains the difference between probiotics and postbiotics, emphasizing that this concentrate delivers postbiotic metabolites (including short-chain fatty acids like butyrate, plus enzymes, amino acids, v...
Jun 03, 2026•29 min
Dr. Hoffman continues his conversation with holistic practitioner Jane Jansen.
Jun 03, 2026•26 min
Naturally Healthy Pets: Whole-Food Diets, Microbiome Repair, and Integrative Therapies with integrative veterinarian Dr. Judy Morgan , DVM, CVA, CVCP, CVFT. She argues that pet ownership benefits human wellbeing and that pets concentrate household toxins, warning against routine pesticide-based flea/tick and other veterinary drugs due to environmental contamination and adverse events. She recommends species-appropriate whole-food diets (cats as obligate carnivores; dogs mostly meat) and criticiz...
Jun 02, 2026•35 min
Dr. Hoffman continues his conversation with integrative veterinarian Dr. Judy Morgan , DVM, CVA, CVCP, CVFT.
Jun 02, 2026•43 min
A tale of 2 pneumonias—NASCAR racer Kyle Busch dead at 41 while Rudy Giuliani, age 81, survives critical care; Newly discovered evidence that Neanderthals were practicing dentistry—59,000 years ago! “Fatty 15”—does it measure up to the hype? Stem Wave—A shocking way to obtain pain relief; When to give antibiotics for a tick bite; Proposed ban on tobacco products for future generations of Brits aims to eradicate smoking.
Jun 01, 2026•43 min
Soon-to-arrive drugs promise to address elevated Lp(a); Best natural alternatives to repel mosquitoes and ticks; When cancer treatments cause osteoporosis; Organoids and computer simulations promise to reduce the toll of live animal experimentation; Land snails and pythons yield clues for new drug development; Shortfall in doctors accelerated by early retirement as physicians cite “hassle factor.”
Jun 01, 2026•45 min
Registered dietitian nutritionist Leyla Muedin discusses the growing interest in biological age versus chronological age and explains that biological aging is modifiable through consistent lifestyle choices. She outlines common measurement tools and biomarkers, including epigenetic clocks (DNA methylation), telomere length, VO2 max, inflammatory markers, grip strength, and muscle mass, noting that genetics account for only about 25–40% of biological aging variation. Key interventions include reg...
May 29, 2026•24 min
An overview of itching Would tofu be a good addition to my diet? Is TMAO a risk factor for heart disease when eating meat? How about interviewing an expert on vegetarianism?
May 28, 2026•37 min
Would you discuss vertebroplasty vs. kyphoplasty? I recently had a fundoplication surgery and now have gastroparesis Could you recommend a healthy aging supplement? How to treat Meibomian Gland Dysfunction/dry eye disease? Should we get wool carpeting or hardwood flooring?
May 28, 2026•32 min
Investigative journalist Charles Piller reveals deep-seated corruption in Alzheimer's research as chronicled in his book, “ Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer's Disease .” The discussion delves into the issues surrounding Big Pharma's influence, fraudulent scientific studies, and the implications of a controversial 2006 experiment at the University of Minnesota. They also address the costly and marginally effective Alzheimer's drugs like Aducanumab, the challe...
May 27, 2026•33 min
Dr. Hoffman continues his conversation with investigative journalist Charles Piller , author of “ Doctored: Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer's Disease .”
May 27, 2026•26 min
Dr. Corey Schuler, PhD(c), FNP, DC, CNS, and director of medical affairs at Allergy Research Group , details his paper “ Energy Allocation Resilience and Endocrine Integration ” in the International Journal of Molecular Sciences. He introduces the Energy Allocation System (EAS), which emphasizes how the body allocates energy—not just produces it—and links many symptoms to impaired bioenergetics and resilience. They discuss mitochondria as energy generators and cellular signaling hubs, the integr...
May 26, 2026•30 min
Dr. Hoffman continues his conversation with Dr. Corey Schuler, PhD(c), FNP, DC, CNS, and director of medical affairs at Allergy Research Group .
May 26, 2026•36 min
Dr. Marty Makary out as FDA Commissioner—was he the victim of a BigPharma purge? Are “liquid biopsies” useful for predicting recurrences, as well as guiding therapy, for cancer? Nighttime smartphone by adolescents surges, eroding kids’ sleep needs; Persistent itch may require an “all of the above” approach to break its vicious cycle—could topical vitamin B12 provide an answer? Study critiques research methods that fast-tracked new Alzheimer’s drugs.
May 25, 2026•43 min
You won’t believe this new medical use for Classic Coca-Cola; The solution for menopausal sleep problems goes beyond mere hormone replacement; Paxlovid strikes out vs. Covid in new trials; Pesticide exposure may explain rising colorectal cancer rates in young people; Big Food touts faulty study that claims healthier food regulations will cost consumers; Higher aerobic fitness boosts size of the brain’s memory centers—as does memorizing London taxi routes.
May 25, 2026•45 min
Eccentric Exercise: Better Results with Less Effort. Leyla Muedin, a registered dietitian nutritionist, discusses eccentric exercise and research suggesting it may deliver better results than strenuous workouts that cause muscle damage and delayed onset muscle soreness (DOMS). She explains contraction types—isometric, concentric, and eccentric—highlighting that eccentric contractions involve muscle lengthening during the lowering phase (e.g., lowering a dumbbell, walking downstairs) and can prov...
May 22, 2026•23 min
Highlights from Dr. Hoffman's Scandinavian trip Should I eliminate the nightshade family of foods from my diet? My friend has been experiencing acid reflux since using a reverse osmosis water filtration system
May 21, 2026•30 min
Where can I access peptide therapy for my wife in California? What are other methods of lowering LDL doing exactly that niacin is not? Should we all be using unbleached toilet paper? Would I benefit from taking minoxidil and finasteride for hair growth? What can I do about my festoons?
May 21, 2026•41 min
Dr. Jacob Teitelbaum , an Integrative Medicine physician, researcher, and best-selling author specializing in chronic fatigue syndrome, details “adrenal fatigue,” contrasting Endocrine Society guidelines focused on overt adrenal failure with his view that the adrenals can be functionally exhausted and may be missed by standard testing and “normal ranges.” They discuss adrenal roles in stress response, blood sugar regulation, blood pressure, immunity, and symptoms suggesting low adrenal function ...
May 20, 2026•33 min
Dr. Hoffman continues his conversation with Dr. Jacob Teitelbaum , an Integrative Medicine physician, researcher, and best-selling author specializing in chronic fatigue syndrome.
May 20, 2026•34 min
Hyperbaric Oxygen Therapy (HBOT): Beyond the Bends—Wounds, Stroke Recovery, Radiation Injury, and Performance. Nicole Garrett, founder and COO of Under Pressure Hyperbarics , details hyperbaric oxygen therapy (HBOT). She explains how HBOT treats divers’ decompression sickness by recompressing nitrogen bubbles and reducing inflammation, and how therapeutic benefits depend on reaching adequate pressure (commonly around 2.0 atmospheres or more; diver treatment may begin at 2.8). Garrett describes H...
May 19, 2026•25 min
Dr. Hoffman continues his conversation with Nicole Garrett, founder and COO of Under Pressure Hyperbarics .
May 19, 2026•29 min
Now do we have to start worrying about Hantavirus? Digestive enzymes for pancreatic insufficiency; Space exploration yields new treatments for resistant bacterial infections; Alternatives to prednisone for autoimmune hearing loss; Casey Means bows out of Surgeon General nomination—next up, Nicole Saphier; Multivitamins found to slow biological aging.
May 18, 2026•43 min
