Immune 95: Mitochondria for everyone
Aug 26, 2025•1 hr 2 min•Ep. 95
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Episode description
Immune discusses how cancer cells swap mitochondria with T cells and then digs in for a discussion of an unusual checkpoint blockade that failed for cancer but could be repurposed for autoimmune inflammation.
Hosts: Vincent Racaniello, Cindy Leifer, Steph Langel, and Brianne Barker
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- Cancer cells steal mitochondria from neurons for metastasis (Nature 2025)
- Cancer cells donate damaged mitochondria to T cells to impair them (Nature 2025)
- PD-L1 binding to CD80 on the same dendritic cell needed for migration (Sci Adv 2025)
- Time stamps by Jolene Ramsey. Thanks!
Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv
Information on this podcast should not be construed as medical advice.
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