016 Training Splits - Why upper/lower, torso/limbs, push/pull, and other split routines face the same problem
Sep 08, 2025•1 hr 14 min•Ep. 17
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Episode description
In this episode of Hypertrophy: Past and Present, Jake and Chris revisit Joe Weider’s early 1940 full-body program before breaking down the central problem that all split routines face: supraspinal CNS fatigue.
Key topics include:
• How calcium-ion–related fatigue and inflammation create global CNS fatigue
• Why back-to-back training days reduce recruitment, even for unrelated muscles
• Why full-body AAA and AB formats avoid these issues
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