#E31 Epigenetic Reprogramming Is the Key to a Longer Lifespan, With Yuri Deigin

On this episode of HYPERSCALE, I am joined by Yuri Deigin, a longevity activist, drug developer, and the Co-Founder and Director of YouthBio Therapeutics, a company developing tissue-specific rejuvenating gene therapies based on partial cellular reprogramming. 

Yuri’s journey with longevity is a personal one. After he lost his grandmother to Alzheimer’s, he underwent a DNA test and discovered that he carried two copies of a specific allele, epsilon four, which is a variant of a gene called Apolipoprotein E (Apo-E). This meant that he was 15 to 20 times more at risk of Alzheimer's than people who didn’t carry this allele, which put his entire life in perspective.

Since that discovery, Yuri has devoted his time and efforts to exploring Alzheimer’s and researching drugs and gene therapies to combat it. Given that Alzheimer’s is a primarily age-related disease, his attention quickly shifted to longevity treatments and cellular reprogramming efforts to address the disease at its root cause. 

Tune in as we explore the mind-blowing potential of gene therapies and manipulation, altering humanity on a basic level. 

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