Hematologic Oncology Update - podcast cover

Hematologic Oncology Update

Featuring one-on-one interviews conducted by Dr Neil Love, this series provides medical oncologists with access to an array of important perspectives and information on relevant advances in the treatment of hematologic cancer to facilitate optimal patient care.
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Episodes

Ocular Toxicities Associated with Antibody-Drug Conjugates and Other Cancer Therapies: Part 1 — Inside the Issue of Adverse Event Management

Prof Rebecca A Dent from National Cancer Centre Singapore, Dr Hans Lee from Sara Cannon Research Institute in Nashville, Tennessee, Dr Neel Pasricha from the University of California, San Francisco, and Dr Tiffany A Richards from The University of Texas MD Anderson Cancer Center in Houston, discuss strategies to manage ocular toxicities associated with antibody-drug conjugates and other cancer therapies. CME information and select publications here ....

Sep 15, 202558 minSeason 25Ep. 44

Multiple Myeloma | Oncology Q&A — Patient Education Resource: Clinical Experts Address Common Questions Posed by Patients with Relapsed/Refractory Multiple Myeloma

For this patient-focused webinar, medical oncologist Dr Neil Love is joined by Dr Natalie S Callander from the University of Wisconsin Carbone Cancer Center in Madison and Dr Sagar Lonial from the Winship Cancer Institute of Emory University in Atlanta, Georgia, to discuss the patient experience associated with the diagnosis and treatment of relapsed/refractory multiple myeloma. Educational and faculty information here ....

Aug 15, 20251 hr 2 minSeason 25Ep. 40

Multiple Myeloma — Proceedings from a Webinar Held in Conjunction with the 2025 ASCO Annual Meeting

Drs. Nooka and Richardson provide an update on multiple myeloma treatment, including recent ASCO highlights. They delve into antibody-drug conjugates (Belantamab Mafodotin), discuss the evolving role of oral cell modulators, and compare CAR-T therapies (Idacel, Siltacel) with bispecific antibodies (Teclistamab, Elranatamab, Talquetamab). The discussion covers clinical efficacy, real-world data, managing unique toxicities, and optimal sequencing in different patient scenarios.

Jul 18, 202559 minSeason 25Ep. 36

Non-Hodgkin Lymphoma — Proceedings from a Session Held During the 2025 ASCO Annual Meeting

Leading lymphoma specialists discuss complex patient cases and clinical data shaping the care of Non-Hodgkin Lymphoma. The episode covers recent advances and strategies for diffuse large B-cell lymphoma, mantle cell lymphoma, and follicular lymphoma, including updates on frontline regimens, BTK inhibitors, bispecific antibodies, and CAR T-cell therapy, addressing sequencing, toxicity management, and long-term care.

Jul 10, 20252 hrSeason 25Ep. 34

IDH-Mutant Low-Grade Glioma — An Interview with Dr Patrick Y Wen on Current and Future Management Strategies

Dr. Patrick Wen discusses the evolution of glioma classification, highlighting the significance of IDH mutation status for prognosis and treatment. He details the development and FDA approval of vorasidenib for IDH-mutant gliomas, including its mechanism of action, clinical trial results, and ongoing debates regarding its optimal use. The episode also covers current management and innovative treatment strategies for glioblastoma, addressing challenges like the blood-brain barrier and the importance of specialized care.

Jun 24, 202554 minSeason 25Ep. 31

Multiple Myeloma — Year in Review Series on Relevant New Datasets and Advances

This episode provides an in-depth review of significant developments in multiple myeloma management over the past year. Experts delve into emerging immunotherapies such as tri-specific antibodies, the re-evaluation of belantamab, and the evolving roles of anti-CD38 therapies in smoldering, induction, and maintenance settings. Discussions also cover the clinical utility of MRD testing, practical aspects of subcutaneous drug administration, and a strategic comparison of CAR-T and bispecific antibodies, including their associated toxicities and future applications.

Jun 18, 202559 minSeason 25Ep. 30

Myelofibrosis — Year in Review Series on Relevant New Datasets and Advances

Professor Claire Harrison from the Guy’s and St Thomas’ NHS Foundation Trust in London, United Kingdom, and Dr John Mascarenas from The Tisch Cancer Institute in New York, New York, provide their perspectives on relevant new clinical data in myelofibrosis and discuss their application to treatment. CME information and select publications here .

Jun 11, 202559 minSeason 25Ep. 29

Non-Hodgkin Lymphoma — Year in Review Series on Relevant New Datasets and Advances

Drs. Stephen Ansell and Brian Hill review major treatment advances in non-Hodgkin lymphoma over the past year, focusing on diffuse large B-cell, mantle cell, and follicular lymphomas. The discussion covers new data on bispecific antibodies, antibody-drug conjugates, and CAR T-cell therapies, highlighting shifts in treatment paradigms, management of toxicities, and the role of MRD testing. They also explore emerging chemotherapy-free regimens and their impact on patient care.

Jun 05, 202559 minSeason 25Ep. 28

Systemic Mastocytosis and Myelofibrosis — Fourth Annual National General Medical Oncology Summit

This episode explores the latest advancements in treating systemic mastocytosis (SM) and myelofibrosis (MF). Clinical investigators delve into targeted therapies like avapritinib for SM, discussing its efficacy in both advanced and indolent forms, as well as managing side effects like brain fog. For MF, the discussion covers the four approved JAK inhibitors—ruxolitinib, fedratinib, pacritinib, and mamelotinib—addressing their benefits, challenges, and impact on patient quality of life. The episode also includes real-world patient cases, illustrating diagnostic complexities and treatment considerations for these rare hematologic conditions.

Jun 02, 202548 minSeason 25Ep. 27

Multiple Myeloma — An Interview with Dr Rafael Fonseca on Key Presentations from the 66th American Society of Hematology (ASH) Annual Meeting

Dr. Rafael Fonseca provides an in-depth update on multiple myeloma from the ASH 2024 meeting. He shares practical insights on integrating bispecific antibodies and CAR-T therapies, discussing their efficacy, toxicity management, and optimal sequencing in different patient settings. The episode also explores the re-emergence of belantamab, the debate on treating smoldering myeloma, and the future of novel immunomodulators, offering a comprehensive overview of current and emerging treatment strategies.

May 29, 202551 minSeason 25Ep. 25

Relapsed/Refractory Follicular Lymphoma Part 3 — A Roundtable Discussion on the Selection and Sequencing of Other Novel Therapies

Dr Carla Casulo from Wilmot Cancer Institute in Rochester, New York, Dr Matthew Matasar from Rutgers Cancer Institute of New Jersey in New Brunswick and Dr Laurie H Sehn from BC Cancer Centre for Lymphoid Cancer in Vancouver discuss recent updates on available and novel treatment strategies for relapsed/refractory follicular lymphoma. CME information and select publications here .

May 23, 202543 minSeason 25Ep. 23

Relapsed/Refractory Follicular Lymphoma Part 2 — A Roundtable Discussion on the Selection and Sequencing of CAR T-Cell Therapy

Dr Carla Casulo from Wilmot Cancer Institute in Rochester, New York, Dr Matthew Matasar from Rutgers Cancer Institute of New Jersey in New Brunswick and Dr Laurie H Sehn from BC Cancer Centre for Lymphoid Cancer in Vancouver discuss recent updates on available and novel treatment strategies for relapsed/refractory follicular lymphoma. CME information and select publications here .

May 16, 202537 minSeason 25Ep. 21

Immune Thrombocytopenia — A Roundtable Discussion on Current and Future Management Strategies

Dr Hanny Al-Samkari from Massachusetts General Hospital in Boston, Dr James B Bussel from Weill Cornell School of Medicine in New York, New York, and Prof Nichola Cooper from Hammersmith Hospital Campus in London, United Kingdom, share expert perspectives on the diagnosis of and optimal management strategies for immune thrombocytopenia. CME information and select publications here .

Apr 28, 20251 hr 57 minSeason 25Ep. 17

Relapsed/Refractory Follicular Lymphoma Part 1 — A Roundtable Discussion on the Selection and Sequencing of Bispecific Antibodies

Drs. Carla Casulo, Matthew Matasar, and Laurie Sehn discuss current and novel bispecific antibody treatments for relapsed/refractory follicular lymphoma, focusing on Mosunetuzumab, Epcoritimab, and Odronextamab. They compare their efficacy, safety profiles, and administration schedules, explore patient selection criteria, and the integration of these therapies into community practice. The discussion is enriched with real-world patient case studies and a look into future clinical trials, including considerations for infection risk and vaccination.

Apr 22, 202540 minSeason 25Ep. 16
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