A Sickness in the Serum, Part 1: Serum Sickness and the Rheumatologist

This episode delves into the clinical presentation of serum sickness along with a dash of Arthus reaction, to boot!

Brought to you by GSK.

• Intro :10
• Today’s episode :26
• Let’s get into some cases 4:11
• The Arthus reaction 6:06
• What is another example of the same thing happening but on a systemic level? 7:25
• Breaking down the clinical features of serum sickness 14:20
• How confident are we that the compliment levels always drop? 16:26
• How common is serum sickness? 19:45
• The mechanistics of rituximab 21:36
• A preview of parts two and three 27:37
• Episode wrap-up 28:38

Disclosures: Brown reports no relevant financial disclosures.

We’d love to hear from you! Send your comments/questions to Dr. Brown at [email protected]. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum

References:

Bayer G, et al. Eur J Intern Med. 2019;67:59-64.

Karmacharya P, et al. Semin Arthritis Rheum. 2015;35-334-340.

Lawley TJ, et al. J Invest Dermatol. 1985;85:129s-132s.