Host: Jay Goldstein, MD Guest: Jonathan Leighton, MD Guest: Moshe Rubin, MD Obscure gastrointesinal bleeding can pose investigational challenges. What are the potential causes of obscure GI bleeding? After initial negative upper endoscopy and colonoscopy tests are performed, what new technologies can help physicians more effectively detect small bowel abnormalities? Dr. Jonathan Leighton, professor of medicine and chair of the division of gastroenterology at the Mayo Clinic in Arizona, and Dr. M...
Sep 21, 20100
Host: Lee Freedman, MD Guest: Brian Lacy, MD, PhD Resistance to proton pump inhibitors, or PPIs, is not uncommon among patients with gastroesophogeal reflux disease, or GERD. How should physicians initially approach managing patients with suspected GERD, and at what point should physicians classify a patient as a PPI non-responder? Our guest, Dr. Brian Lacy, associate professor of medicine at Dartmouth Medical School, and director of the GI Motility Laboratory at Dartmouth-Hitchcock Medical Cent...
Sep 16, 20100
Host: Jay Goldstein, MD Guest: Joel Brill, MD How do we categorize and define value-based purchasing, and how can it help us avoid unnecessary costs and foster better quality of care? What are some examples, and how do guidelines work in conjunction with value-based purchasing? Dr. Joel Brill, assistant clinical professor of medicine at the University of Arizona School of Medicine and chief medical officer of Predictive Health, LLC, talks about how we can best characterize and measure the still-...
Aug 19, 20090
Host: Jay Goldstein, MD Guest: Maria T. Abreu, MD Dr. Maria Abreu, professor of medicine and chief of the division of gastroenterology at the University of Miami Miller School of Medicine, joins host Dr. Jay Goldstein to discuss inflammatory bowel disease, or IBD, and women's reproductive health. Does inflammatory bowel disease, or IBD, affect female fertility? What influence does IBD have on the course of pregnancy, and how does pregnancy, in turn, affect the natural history of IBD? Which medic...
Aug 19, 20090
Host: Mark DeLegge, MD Guest: Rebecca West, JD The cost of malpractice insurance and the cost of resolving malpractice claims continues to climb. What are the trends in premiums for gastroenterologists around the country? And what are some of the most common risks and most commonly alleged errors? What’s the likelihood of a gastroenterologist being sued during his career? Rebecca West, CEO of Piedmont Liability Trust, a non-profit serving the University of Virginia School of Medicine, joins host...
Aug 06, 20090
Host: Mark DeLegge, MD Guest: Jack Grider, PhD What is the underlying mechanism of propulsion in the digestive system, and how is motility stimulated? How are some newer pharmacotherapies looking to target serotonin to treat conditions such as IBS and constipation? Dr. Jack Grider, professor in the department of medicine, division of gastroenterology at the Virginia Commonwealth University School of Medicine, talks about future pharmacotherapy directions that either suppress or encourage motilit...
Aug 04, 20090
Host: Mark DeLegge, MD Guest: Miriam Vos, MD, MSPH Although it's important to consider the many factors that contribute to childhood obesity when designing a weight loss plan, sugar may be one of the most important components to target. Specifically, how does fructose influence childhood obesity? Dr. Miriam Vos, assistant professor in the department of gastroenterology at Emory University and author of the book The No-Diet Obesity Solution for Kids , published by the AGA Institute Press, offers ...
Aug 04, 20090
Host: Jay Goldstein, MD Guest: Mansour Mohamadzadeh, PhD Researchers have developed an oral vaccine utilizing probiotics and, in preclinical studies, have found it successful in providing immunity against anthrax. Why are probiotics a good delivery component, and why might this method encourage a greater degree of response than the traditional vaccine injection? Dr. Mansour Mohamadzadeh, associate professor of medicine in the division of gastroenterology at Northwestern University Feinberg Schoo...
Jul 13, 20090
Host: Jay Goldstein, MD Guest: Elizabeth Montgomery, MD Gastroenterologists and pathologists often rely on each other to care for patients. How can clinicians and pathologists best facilitate each other's work for the good of the patient? Dr. Elizabeth Montgomery, professor of pathology and oncology at Johns Hopkins University School of Medicine, explores the interaction between gastroenterologists and pathologists with host Dr. Jay Goldstein. Also, Dr. Montgomery outlines biopsy tips for gastro...
Jul 13, 20090
Host: Jay Goldstein, MD Guest: Linda Lee, MD How does delayed gastric emptying, or gastroparesis, affect patients? What are some of the common comorbid conditions of gastroparesis, and why are women and diabetic patients more susceptible? Dr. Linda Lee, clinical director of the division of gastroenterology and hepatology and director of the Johns Hopkins Integrative Medicine and Digestive Center at the Johns Hopkins University School of Medicine, reviews the best gastroparesis diagnostic tools a...
Jul 13, 20090
Host: Mark DeLegge, MD Guest: William Chey, MD Guest: Mark Pimentel, MD Irritable bowel syndrome, or IBS, affects a significant number of patients and can be challenging to treat. How might antibiotic therapy benefit IBS patients, and how is antibiotic therapy a unique option for treating IBS? Should physicians empirically treat IBS patients with antibiotics? Joining us to debate these questions are Dr. William Chey, professor in the department of internal medicine at the University of Michigan ...
Jun 25, 20090
Host: Mark DeLegge, MD Guest: Charles Bernstein, MD Probiotics are becoming increasingly popular, but is there any substantial evidence supporting the efficacy of probiotics for irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD)? Are there any potential risks to IBS and IBD patients using probiotic therapy? Which probiotic strains might be most beneficial, and what dosage is optimal? Dr. Charles Bernstein, director of the University of Manitoba Inflammatory Bowel Disease Clinica...
Jun 25, 20090
Host: Mark DeLegge, MD Guest: Alphonso Brown, MD, MS The causes of pancreatitis are often unknown, but we're learning that there are more potential causes than previously believed. Genetic causes are rare, but their detection has improved with new technology. What role might genetic testing play in correctly diagnosing and managing the condition? And what are the ramifications of genetic testing for the patient? Dr. Alphonso Brown, assistant professor of medicine at Harvard Medical School and co...
Jun 25, 20090
Host: Jay Goldstein, MD Guest: Mark DeLegge, MD What unique perspectives can gastroenterologists offer to help manage and treat obesity, and how can gastroenterologists address the needs of their obese or overweight patients? When should a surgical bypass or lap-band procedure be considered? Host Dr. Jay Goldstein welcomes his GI Insights co-host, Dr. Mark DeLegge, to discuss the role of the gastroenterologist in preventing and treating obesity. You can access the AGA’s new materials about nutri...
Apr 30, 20090
Host: Jay Goldstein, MD Guest: Deborah Proctor, MD Host Dr. Jay Goldstein welcomes Dr. Deborah Proctor, professor of medicine in the section of digestive diseases and medical director of the Inflammatory Bowel Disease Program at Yale University School of Medicine, to provide an overview of common female gastroenterological disorders. They discuss which gastroenterological disorders present differently in women than in men. How do pelvic surgeries, such as C-sections or hysterectomies, affect col...
Apr 30, 20090
Host: Jay Goldstein, MD Guest: Christian Stone, MD, MPH Incidents of Clostridium difficile, or C.diff , are increasing in the US. Are patients with ulcerative colitis or Crohn's disease more at risk for developing C. difficile infection than other patients? Is this due to an increased use of antibiotics in hospitals, or are other factors playing a role? Join host Dr. Jay Goldstein as he welcomes Dr. Christian Stone, associate professor of medicine at Washington University School of Medicine in S...
Apr 30, 20090
Host: Mark DeLegge, MD Guest: Andrew Chan, MD, MPH Guest: David Lieberman, MD It's currently recommended that patients at average risk for colorectal cancer repeat a colonoscopy every 10 years. Is the 10-year interval appropriate for average-risk patients, or would patients benefit from more frequent colonoscopies? What evidence do we have to support the idea that more frequent colonoscopies would provide more accurate screening? Or, would a shorter intervals between colonoscopies unnecessarily ...
Mar 05, 20090
Host: Mark DeLegge, MD Guest: T. Karl Byrne, MD What are the advantages to each of the two main types of obesity surgeries— gastric bypass and lap band surgery? How do the recovery times, efficacy and potential complications compare? Host Dr. Mark DeLegge welcomes Dr. T. Karl Byrne, professor of surgery and medical director of the Bariatric Surgery Center at the Medical University of South Carolina, to discuss the role of the gastric bypass and lap band procedures in treating obesity. Are some p...
Mar 05, 20090
Host: Mark DeLegge, MD Guest: Douglas Rex, MD Fecal immunochemical testing (or FIT testing) replaces the older stool guaiac test in the recent colorectal cancer screening guidelines. What's the advantage to FIT testing? Is there a place for fecal DNA testing in the realm of colorectal cancer screening methods right now, or does this procedure need further revision? Host Dr. Mark DeLegge discusses the newest developments in colorectal cancer screening technologies with Dr. Douglas Rex, distinguis...
Feb 12, 20090
Host: Mark DeLegge, MD Guest: Lisa Boardman, MD Early detection through screening for colorectal cancer (CRC) can make a huge impact in preventing the development or progression of CRC. What screening methods are most recommended? Dr. Lisa Boardman, assistant professor of medicine at the Mayo Clinic, reviews details of the CRC screening guidelines from both the Joint Effort Panel, as well as the United States Preventive Services Task Force. Will these guidelines be dramatically revised in the ne...
Feb 12, 20090
Host: Jay Goldstein, MD Guest: Robert Bresalier, MD What are some common gastrointestinal complications from oncologic therapies? How can physicians differentiate a side effect from a condition that requires further evaluation? Host Dr. Jay Goldstein welcomes Dr. Robert Bresalier, professor of medicine in the department of gastrointestinal medicine and nutrition at the M.D. Anderson Cancer Center, to discuss the role of the gastroenterologist in treating cancer and complications from oncologic t...
Feb 11, 20090
Host: Jay Goldstein, MD Guest: J. Randolph Hecht, MD How have treatments for colorectal and pancreatic cancers advanced in recent years, and are novel treatments reducing the mortality rate of patients with these cancers? Dr. J. Randolph Hecht, director of the GI Oncology Program at the UCLA Health System and clinical professor of medicine in the hematology-oncology division at the UCLA David Geffen School of Medicine, looks at some of the newer pharmacological agents and methods being used to t...
Feb 11, 20090
Host: Mark DeLegge, MD Guest: Michael Camilleri, MD What are some of the newer bariatric endoscopic procedures, and when are these procedures preferred over traditional gastric bypass surgery? Dr. Michael Camilleri, professor of medicine and physiology at the Mayo Clinic Medical School in Rochester, Minnesota, reviews the most common gastric bypass procedures, such as the Roux-en-Y, laproscopic banding and duodenal switch procedures, and explains the advantages to some of the newer surgeries, in...
Jan 27, 20090
Host: Mark DeLegge, MD Guest: Timothy Rubin, MD The micro-organism Clostridium difficile, or C. diff, can cause serious infection and is often resistant to antibiotic therapy. A less traditional approach to treatment — the stool transplant — has emerged as a very successful therapy for patients suffering from C. diff. What does the procedure involve, and which patients might be candidates? Host Dr. Mark DeLegge explores this unconventional therapy with Dr. Timothy Rubin, gastroenterologist at Sa...
Jan 27, 20090
Host: Jay Goldstein, MD Guest: Emmet Keeffe, MD What do recent measures recommend to primary care physicians and gastroenterologists who care for patients with hepatitis C? Dr. Emmet Keeffe, professor of medicine emeritus at Stanford University Medical Center, joins host Dr. Jay Goldstein to outline the 10 measures for diagnosing and treating patients with hepatitis C.
Jan 19, 20090
Host: Jay Goldstein, MD Guest: John Inadomi, MD Non-cardiac chest pain and chronic cough are just two of the extraesophageal manifestations of gastroesophageal reflux disease, or GERD. What other symptoms should we look for? If a patient displays characteristics of GERD, such as esophogeal regurgitation, is that patient also likely to experience extraesophogeal manifestations of GERD? Dr. John Inadomi, the Dean M. Craig Endowed Chair in Gastrointestinal Medicine at the University of California, ...
Jan 19, 20090
Host: Mark DeLegge, MD Guest: David Peura, MD Constipation is a common symptom that presents more often in women and as patients get older. What are the primary and secondary causes of chronic constipation? What are some of the differentiating factors between chronic constipation and IBS-C? Dr. David Peura, professor of medicine at the University of Virginia School of Medicine, joins host Dr. Mark DeLegge to discuss algorithms for diagnosing chronic constipation. When are lifestyle changes not e...
Dec 16, 20080
Host: Mark DeLegge, MD Guest: Rowen Zetterman, MD Acetaminophen, vitamin supplements and antibiotics are just a few of the medications that can cause liver injury. What are the signs of drug-induced liver injury? Are the effects immediate, or do the effects become noticeable after an extended period of time? Dr. Rowen Zetterman, professor of internal medicine at the University of Nebraska Medical Center, provides an overview of factors that might lead to drug-induced liver injury. Dr. Mark DeLeg...
Dec 16, 20080
Host: Mark DeLegge, MD Guest: Mark Donowitz, MD Are there fewer physician-scientists today than there were a few decades ago? What does the future landscape look like for medical research? Dr. Mark Donowitz, LeBoff Professor of Medicine and director of the Center for Epithelial Disorders at the Johns Hopkins University School of Medicine, as well as immediate past-president of the American Gastroenterological Association, discusses some of the barriers and challenges physician-scientists face, a...
Dec 16, 20080
Host: Mark DeLegge, MD Guest: Donald Castell, MD How common is Barrett's esophagus in patients with chronic gastroesophageal reflux disease (GERD) or asymptomatic reflux? What risk factors might predict a diagnosis of Barrett's esophagus? Dr. Donald Castell, professor of medicine and director of the esophageal disorder program at the Medical University of South Carolina, joins host Dr. Mark DeLegge to discuss this potentially pre-cancerous condition.
Dec 16, 20080
