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Genetics Unzipped

The Genetics Societygeneticsunzipped.com
From Mendel's peas to personal genome sequencing, Genetics Unzipped brings you stories from the world of genes, genomes and DNA. In association with The Genetics Society.
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Episodes

S6.27: Next Generation Sequence: Forging new paths in genetics

Please fill out our listener survey at geneticsunzipped.com/survey before January 31st This episode is all about the next generation, as we meet three up-and-coming scientists who have been supported by the Genetics Society, and learn all about Bermuda skinks, the Black Death and life after a genetics PhD. Full show notes, transcript and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzip This episode of Genetics Unzipped was written, presented and produced by Sally Le ...

Jan 25, 202438 minSeason 6Ep. 27

S6.26: The battle for biology: How Mendel came to rule the world

Please take a minute or two to fill out our listener survey and help shape the future of the podcast: https://geneticsunzipped.com/survey In this episode, we talk to Greg Radick from the University of Leeds to explore the impact that Gregor Mendel and his populariser William Bateson have had on the past century of genetics, and ask whether there could have been a more Weldonian view of the world. Full show notes, transcript and references online at GeneticsUnzipped.com Follow us on Twitter @Gene...

Jan 11, 202443 minSeason 6Ep. 26

S6.25: 2023 Unzipped

Please take a minute or two to fill out our listener survey and help shape the future of the podcast: https://geneticsunzipped.com/survey As 2023 draws to a close, we’re bringing you a smorgasbord of previously unaired clips from some of our favourite interviews this year. Full show notes, transcript and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzip This episode of Genetics Unzipped was written, presented and produced by Sally Le Page & Kat Arney with audio pr...

Dec 21, 202336 minSeason 6Ep. 35

S6.24: Genes, junk and the ‘dark genome’

Please take a minute or two to fill out our listener survey and help shape the future of the podcast: https://geneticsunzipped.com/survey We discover how 500,000 whole genome from UK Biobank will help medical research, plumb the depths of the ‘dark genome’ with Nucleome, and Larry Moran tells us how much of our DNA is just junk. Please fill out our short listener survey here Full show notes, transcript and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzip This episode...

Dec 14, 202338 minSeason 6Ep. 24

S6.23: 40 years of HIV: the disease that broke the rules

Please take a minute or two to fill out our listener survey and help shape the future of the podcast: https://geneticsunzipped.com/survey With 2023 marking 40 years since the discovery of HIV, we're looking back over four decades of AIDS, from the earliest whispers of a mysterious new disease to fighting back against this deadly virus. Full show notes, transcript and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzip This episode of Genetics Unzipped was written, prese...

Nov 30, 202335 minSeason 6Ep. 23

S6.22: Dumb luck: Amazing adaptations from happy little accidents

Author and science journalist Rebecca Coffey chats with us about some amazing adaptations and Darwinian delights from her book, Beyond Primates. She tells us about wasp facial recognition genes, how yeast epigenetics explain the Dutch Hunger Winter and a dinner party tale of spider cannibalism. Full show notes, transcript and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzip This episode of Genetics Unzipped was written, presented and produced by Sally Le Page with au...

Nov 16, 202329 minSeason 6Ep. 22

S6.21: Time of your life: how circadian rhythms shape the world

In this episode we’re clocking in to chat about the genetics of circadian rhythms. How can molecules tell the time, why don’t we have drugs for jet lag yet and could a midnight snack stop malaria in its tracks? Full show notes, transcript and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzip This episode of Genetics Unzipped was written, presented and produced by Sally Le Page with audio production by Emma Werner. This podcast is created by First Create the Media for ...

Nov 02, 2023

S6.20: That’s so extra: Exploring the weird world of extrachromosomal DNA

We explore the weird and wonderful world of extrachromosomal DNA - what it is, what it does, and why it breaks the normal rules of inheritance. Full show notes, transcript and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzip This episode of Genetics Unzipped was written and presented and produced by Kat Arney with audio production by Emma Werner. This podcast is produced by First Create the Media for the Genetics Society - one of the oldest learned societies dedicate...

Oct 19, 202333 minSeason 6Ep. 20

S6.19: Food for the future: Helping plants adapt to a changing world

We’re finding out how plants adapt to a changing environment, and how we might be able to give them a helping hand so that we can keep feeding the world sustainably in the future. Full show notes, transcript and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzip This episode of Genetics Unzipped was written and presented and produced by Kat Arney with audio production by Emma Werner. This podcast is produced by First Create the Media for the Genetics Society - one of t...

Oct 05, 202344 minSeason 6Ep. 19

BONUS Hormones: The Inside Story - Is my diabetes my fault?

In this bonus episode, we’re bringing you the third instalment of Hormones: The Inside Story, Season 3. This podcast is produced for the Society for Endocrinology by the same team behind Genetics Unzipped. Find it on Podbean , Apple Podcasts , Spotify or wherever you get your podcasts. In this episode, Dr Sally Le Page investigates the role of genetics, ethnicity and maternal environment on type 2 diabetes, with our guests Dr Inês Cebola, Dr Shivani Misra and Dr Lorna Smith. This week, we invest...

Sep 21, 202340 min

S6.18: An Evolutionary Revolutionary: Alfred Russel Wallace and the discovery of natural selection

We’re exploring the epic life of Alfred Russel Wallace; adventurer, naturalist and co-discoverer of natural selection. Biologist and author, Jim Costa, recounts the life of this often forgotten founding father of evolution. Full show notes, transcript and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzip This episode of Genetics Unzipped was written, presented and produced by Emma Werner and Sally Le Page. This podcast is created by First Create the Media for the Gene...

Sep 07, 202332 minSeason 6Ep. 18

S6.17: Vax to the future: The science of DNA and RNA vaccines

We look at the science behind DNA and RNA vaccines - How do they work? What can they do? And how can they be made at scale so that more people around the world can benefit from them? With John Tregoning from Imperial College London, Christian Ottensmeier from the University of Liverpool, and Lisa Caproni from Touchlight. Full show notes, transcript and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzip This episode of Genetics Unzipped was written and presented by Kat ...

Aug 24, 202333 minSeason 6Ep. 17

S6.16 Double helix double crossing? What really happened between Rosalind Franklin, James Watson and Francis Crick?

Kat Arney chats with Professor Matthew Cobb about what really happened between James Watson, Francis Crick and Rosalind Franklin during the discovery of the double helix structure of DNA. Full show notes, transcript and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzip This episode of Genetics Unzipped was written and presented by Kat Arney with audio production by Emma Werner and Sally Le Page. This podcast is produced by First Create the Media for the Genetics Socie...

Aug 10, 202352 minSeason 6Ep. 16

S6.15: Cordelia Langford: Making Big Science Happen

We’re going behind the scenes at the Sanger Institute with Cordelia Langford, Director of Scientific Operations, to find out what it takes to make Big Science happen, and hear the stories behind the sequencing. Full show notes, transcript and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzip This episode of Genetics Unzipped was written and presented by Kat Arney with audio production by Emma Werner and Sally Le Page. This podcast is produced by First Create the Media...

Jul 27, 202326 minSeason 6Ep. 15

S6.14: Tracking COVID and tackling obesity: Meet this year’s Genetics Society award winners

We’re chatting with two of this year’s Genetics Society award winners - Cecilia Lindgren, who’s an expert on the genetics of obesity and metabolic disorders, and Lucy van Dorp, who has spent the past three years tracing the spread of SARS-CoV-2 around the world. Full show notes, transcript and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzip This episode of Genetics Unzipped was written and presented by Kat Arney with audio production by Emma Werner and Sally Le Page...

Jul 13, 202333 minSeason 6Ep. 14

S6.13: Kings, car parks and consent: should we sequence DNA from human remains?

We’re venturing into ancient territory and archaeological digs, excavating the complex ethics of extracting and sequencing DNA from human remains. We chat to Prof. Turi King about her role uncovering the body King Richard III and who decides which research gets done. Full show notes, transcript and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzip This episode of Genetics Unzipped was written, presented and produced by Emma Werner and Sally Le Page. This podcast is cr...

Jun 29, 202328 minSeason 6Ep. 13

S6.12: Da Vinci’s DNA: What happens when genetics meets art

We’re taking a journey into the world of art and artefacts, unearthing the genetic secrets of long-dead legends like Da Vinci, Van Gogh and Beethoven. Full show notes, transcript and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzip This episode of Genetics Unzipped was written and presented by Kat Arney with audio production by Emma Werner and Sally Le Page. This podcast is produced by First Create the Media for the Genetics Society - one of the oldest learned societ...

Jun 15, 202326 minSeason 6Ep. 12

S6.11: Meet the DNA Detectives hunting the causes of cancer

We’re chasing down the perpetrator of a scientific Whodunnit, joining the DNA detectives on the hunt for the causes of cancer. Full show notes, transcript and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzip This episode of Genetics Unzipped was written and presented by Kat Arney with audio production by Emma Werner and Sally Le Page. This podcast is produced by First Create the Media for the Genetics Society - one of the oldest learned societies dedicated to promoti...

Jun 01, 202333 minSeason 6Ep. 611

S6.10: Space invaders: The amazing adaptations of tardigrades

In this episode we’re going microscopic, exploring what tiny tardigrades can teach us about desiccation, vaccine delivery … and even space travel! Full show notes, transcript and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzip This episode of Genetics Unzipped was written, presented and produced by Emma Werner and Sally Le Page. This podcast is created by First Create the Media for the Genetics Society - one of the oldest learned societies dedicated to promoting res...

May 18, 202329 minSeason 6Ep. 10

S6.09: Raiders of Noah’s Ark: Stealing genetic tricks from the animal kingdom

In this episode we’re becoming chromosomal criminals and learning about how researchers are stealing genes from the animal kingdom and using them to improve human health. From 13-lined ground squirrels teaching us how to recover from heart attacks, to bowhead whales showing us how to avoid cancer, there’s a lot geneticists can learn from Mother Nature. Full show notes, transcript and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzip This episode of Genetics Unzipped w...

May 04, 202327 minSeason 6Ep. 9

BONUS Re-release S3.22 - The Past, Present and Future of the Human Genome Project

To celebrate DNA Day, we are rereleasing an episode from series 3, called The Past, Present, and Future of the Human Genome Project, when Kat interviewed the director of the US National Human Genome Research Institute, Dr Eric Green about his work on the Human Genome Project from its very inception. Full show notes, transcript and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzip This podcast is created by First Create the Media for the Genetics Society - one of the o...

Apr 27, 202329 minSeason 3Ep. 22

S6.08: Pop goes the genome! Genetics in popular culture

We take a leftfield look at public communication of genetics, exploring how the science of DNA turns up in popular culture from comics and music to cakes, with Great British Bake Off winner Syabira Yusoff. Full show notes, transcript and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzip This episode of Genetics Unzipped was written and presented by Kat Arney with audio production by Emma Werner and Sally Le Page. This podcast is produced by First Create the Media for ...

Apr 20, 202334 minSeason 5Ep. 8

S6.07: Chris Hemsworth took a genetic test for Alzheimer's. Should you?

We’re discussing Chris Hemsworth’s recent Alzheimer's risk findings and the pros and cons of direct-to-consumer DNA testing with genetic counsellor and host of the podcast DNA Today, Kira Dineen. Full show notes, transcript and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzip This episode of Genetics Unzipped was written, presented and produced by Emma Werner and Sally Le Page. This podcast is created by First Create the Media for the Genetics Society - one of the ol...

Apr 06, 202338 minSeason 6Ep. 7

S6.06: Bye-bye boys: The genetics behind the extinction of males

We’re saying bye-bye to the boys, and exploring whether new gene technologies and climate change will make males extinct. Full show notes, transcript and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzip This episode of Genetics Unzipped was written, presented and produced by Emma Werner and Sally Le Page. This podcast is created by First Create the Media for the Genetics Society - one of the oldest learned societies dedicated to promoting research, training, teaching...

Mar 23, 202336 minSeason 6Ep. 6

S6.05: GMO or GM NO? The ethics and realities of genome editing

We're exploring the ethics and regulations of genome editing. What is allowed? What shouldn't be? And who should get to decide? Plus we explore a new exhibit on the topic that lets the public have their say. Full show notes, transcript and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzip This episode of Genetics Unzipped was written, presented and produced by Emma Werner and Sally Le Page. This podcast is created by First Create the Media for the Genetics Society - o...

Mar 09, 202337 minSeason 6Ep. 5

S6.04: The diagnostic odyssey: A journey into genetic testing for rare diseases

We’re off on a journey to the world of rare genetic disorders, exploring the diagnostic odyssey that patients go on in search of answers, research into variants of unknown significance and new approaches for treating the rare disease Aicardi-Goutières Syndrome (AGS) Full show notes, transcript and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzip This episode of Genetics Unzipped was written and presented by Kat Arney with audio production by Emma Werner and Sally Le ...

Feb 23, 202338 minSeason 6Ep. 4

S6.03: Confident, competent or confused: What do you think you know about genetics?

How much do you know about genetics? In this episode we’re sharing the results of a large survey asking the UK public what their opinions are, what they know, or more importantly, what they think they know about genetics and what that means for society. Full show notes, transcript and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzip This episode of Genetics Unzipped was written and presented by Sally Le Page with audio production by Emma Werner and Sally Le Page. Thi...

Feb 09, 202339 minSeason 6Ep. 3

S6.02: Would you Adam and Eve it? In search of our earliest genetic ancestors

We’re going back to the very genesis of our species in search of the genetic Adam and Eve. Who were they? When and where did they live? Were there really just two of them? And how should we really be referring to these ancient ancestors anyway? Full show notes, transcript and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzip This episode of Genetics Unzipped was written and presented by Kat Arney with audio production by Emma Werner and Sally Le Page. This podcast is ...

Jan 26, 202330 minSeason 6Ep. 2

S6.01 Baby brain, baby body: the genetics (and epigenetics) of reproduction

We’re going back to the womb to explore the genetics of how to make babies - from finding out how birthweight is linked to the risk of diabetes to investigating the multifaceted role of the hormone prolactin in pregnancy and the role of epigenetics in the placenta. Full show notes, transcript and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzip This episode of Genetics Unzipped was written and presented by Kat Arney with audio production by Emma Werner and Sally Le P...

Jan 12, 202331 minSeason 6Ep. 1

S525: 2022 Unzipped

Full show notes, transcript and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzip This episode of Genetics Unzipped was written, presented and produced by Sally Le Page. This podcast is created by First Create the Media for the Genetics Society - one of the oldest learned societies dedicated to promoting research, training, teaching and public engagement in all areas of genetics....

Dec 15, 202240 minSeason 5Ep. 25
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