Genetics (Audio) - podcast cover

Genetics (Audio)

University of California faculty present the latest findings in genetic research and discoveries.
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Episodes

CARTA: The Evolution of Human Physical Activity - Yana Kamberov - Genetic Drivers of Human Thermoregulatory Skin Traits

Human physical activities differ significantly from other species. How, when and why did these capabilities evolve? What adaptations underlie them? And how did the evolution of human physical activity affect other key human characteristics that have advanced our species? Yana Kamberov explores how sweating evolved and what it means for Homo sapiens. Humans use sweating as the primary mechanism to dump body heat. Humans’ ability to effectively harness sweating as a thermoregulatory mechanism is a...

Jun 21, 202125 min

CARTA: The Evolution of Human Physical Activity - Tatum Simonson - Human Adaptation to High Altitudes and Aquatic Environments

Human physical activities differ significantly from other species. How, when and why did these capabilities evolve? What adaptations underlie them? And how did the evolution of human physical activity affect other key human characteristics that have advanced our species? Tatum Simonson explains adaptations to altitude and diving. Humans have persisted for hundreds of generations under challenging environmental extremes. Adaptations to such environments have been essential for survival, enabling ...

Jun 19, 202119 min

Precision Genomics and Immunotherapy: Cancer and Beyond - Exploring Ethics

Breakthroughs in genomics and targeted therapies are revolutionizing the practice of clinical oncology. Precision genomics and immunotherapy offer promise to improve outcomes in cancer, but doing so means we need to move beyond historical models for cancer diagnosis and treatment. Razelle Kurzrock, MD discusses insights from this rapidly changing field and addresses some of the ethical challenges that must be met if we are to transform the lives of patients with cancer. Series: "Exploring Ethics...

May 31, 20211 hr 18 min

A Closer Look at...Spinal Cord Injury

Mark Tuszynski, MD, Ph.D., Bob Yant, and Lawrence S.B. Goldstein, Ph.D. discuss the newest research and treatments for spinal cord injury, including how neural stem cells may be leveraged to potentially regain function. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37102]

May 30, 20211 hr 21 min

CARTA: Altered States of the Human Mind: Implications for Anthropogeny: Kenneth Kidd - Alcohol Metabolism and Alcoholism

Experts address altered states of the mind that are deliberately induced by humans. We will address what is known about origins and mechanisms of these mind-altering practices. In doing so, we hope to gain new insights into the origins and workings of the human mind. Series: "CARTA - Center for Academic Research and Training in Anthropogeny" [Health and Medicine] [Science] [Show ID: 36671]

Apr 13, 202127 min

Stem Cell and Gene Therapy - Matthew Porteus Tippi Mackenzie Matthew Spear Stephen Gottschalk

Stem cells may play a critical role in treating genetic diseases. Hear from experts in the field. Moderated by Matthew Porteus, MD, PhD, Stanford University Tippi MacKenzie, MD, UC San Francisco: Fetal Therapy for Alpha Thalassemia Major Matthew A. Spear, MD, Poseida Therapeutics: CAR-T Cells: Poseida Therapeutics Stephen Gottschalk, MD, St. Jude Children's Research Hospital: Gene Therapy for X-linked SCID Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 36351]

Oct 19, 202055 min

Blood and Immune System Disorders - Crystal Mackall Alysia Vaccaro Jennifer Puck Donald Kohn Mark Walters

What impacts has stem cell research made for blood and immune system disorders? Hear the latest from experts in the field. Moderated by Crystal Mackall, MD, Stanford University Alysia Vaccaro: Patient Perspective Jennifer M Puck, MD, UC San Francisco: Gene Therapy for Artemis Severe Combined Immunodeficiency (ART-SCID) Donald B. Kohn, MD, UCLA: Hematopoietic Stem Cell Gene Therapy for Primary Immune Deficiencies Mark C. Walters, MD, UCSF Benioff Children's Hospital Oakland: Gene correction in Si...

Oct 10, 20201 hr 6 min

The Evolution of SARS-CoV-2

In this presentation from the course The Evolution of Infectious Diseases, professor of biology and infectious disease researcher Justin Meyer provides a detailed overview of the previous, current and future evolution of the SARS-CoV-2 virus. Series: "The Evolution of Infectious Diseases with Justin Meyer" [Health and Medicine] [Science] [Show ID: 36095]

Jun 15, 202057 min

Your Genetic Privacy in the Big Data Era - Exploring Ethics

In the United States, privacy is considered a fundamental right. Yet today our activities are followed to a degree unfathomable not long ago by way of cell phones, online behaviors, and more. As genomic technologies continue to expand, another avenue now exists by which we may potentially be scrutinized: DNA sequence. Our genetic information contains our most private details, but we leave it everywhere and share the sequence closely with dozens or even hundreds of relatives. Laura Rivard, PhD, p...

Nov 23, 201953 min

Sensory Implications of Brain Organoids with Patricia Churchland

What defines consciousness? Can it develop in a petri dish? Patricia Churchland reviews the current state of brain organoid research and shares her views on how conciseness and physical structures within the brain intersect. She also cautions the media on the tendency to "over hype" new research advances. Series: "Women in Science" [Health and Medicine] [Humanities] [Show ID: 35247]

Nov 08, 201945 min

The Current Status of Human Brain Organoids Research with Alysson Muotri and Larry Goldstein

The study of brain organoids is leading to a better understanding of human development and potential therapies for neurological disorders. Yet when people hear the phrase "brain in a dish" it instantly brings to mind the stuff of science fiction - labs full of sentient brains thinking and plotting. Alysson Muotri explains why these organoids should not called "brains in a dish" and how they are being used to explain human processes previously inaccessible to study. While underscoring scientific ...

Nov 01, 201936 min
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