Explore the realm of epigenetics and gene expression, discovering the different omic ‘lenses’ used to examine these processes and the power of single-cell studies to reveal provide a comprehensive multiomic view of cells and their biology. This episode features the ever-buoyant Will Greenleaf, Associate Professor of Genetics at Stanford University School of Medicine (CA, USA) and head of the Greenleaf Lab. Will takes us through his lab’s work, detailing his attempts to understand the compacting ...
Jun 11, 2021•33 min
Cryopreservation of advanced therapy medicinal products: an interview with Brian Hawkins by Taylor & Francis Group
Jun 10, 2021•10 min
This episode, supported by Bethyl, delves into the realm of the tumor microenvironment (TME), exploring the cells that reside there and how they interact to promote tumor growth and metastasis. Discover how immune cells are attracted and manipulated by tumor cells enabling the cancer to invade neurons where they can then travel throughout the body. Providing an expert's insight into this topic is Moran Amit, Assistant Professor at the MD Anderson Cancer Center (TX, USA). Moran exposes the nebulo...
May 28, 2021•29 min
Rare diseases present a series of challenges on numerous fronts. From simply deciphering what a patient is affected by to considering how best to manage a rare condition with limited pre-existing medications available for a rare disease, each new development or breakthrough brings clinicians to a new question. While these conditions are, in isolation, rare; in total rare diseases impact 25-30million people in the USA alone. Supported by Psomagen and featuring four fascinating guests from across ...
May 19, 2021•39 min
In the Zone: phosphorylated biomarkers by Taylor & Francis Group
Apr 29, 2021•16 min
In this episode, we explore the often overlooked technique of environmental sequencing for infectious diseases and how it is being applied to the response to COVID-19. Taking the state of California and a case study of this application, I speak to Micheal Lisek, Project Manager Environmental Microbiomics at Zymo Research Corp. Micheal outlines the basis of environmental sequencing, predominantly the screening of wastewater for signs of viral RNA, the key techniques involved in the process and ch...
Apr 19, 2021•29 min
In this podcast, Tristan Free – Digital Editor at RegMedNet – speaks to Abbie Underhill (Scientific Bioprocessing) about the role that sensors have in regenerative medicine, including the biggest challenges behind implementing sensors in cell culture systems.
Apr 14, 2021•11 min
In Part 3 of our COVID-19 diagnostics and detection miniseries, supported by Roche, we explore the contribution PCR has made towards diagnosis during the pandemic. Providing me with an insight into the world of PCR diagnostics is Tyler Miller, Clinical Pathology Resident and Research Fellow at Massachusetts General Hospital, where he was instrumental in setting up the testing regimen for the Hospital. Ty details the attributes of PCR that lead to it becoming the gold standard for diagnostic test...
Mar 30, 2021•30 min
Returning to the contentious topic of the Reproducibility crisis – the inability of many study results to be replicated by different research groups or labs – this episode, supported by Zymo Research, zeros in on the topic within the field of microbiomics. Speaking to me about the topic is Raul Cano, Chief Scientific Officer at the BioCollective. Raul discusses the crisis and explains why it is prevalent in the emerging field of microbiomics before taking a look at the key role that microbiomics...
Mar 25, 2021•27 min
Spotlight: precision medicine and companion diagnostics by Taylor & Francis Group
Mar 22, 2021•11 min
Virtual audits: limitations and future trends by Taylor & Francis Group
Mar 11, 2021•9 min
This International Women’s Day takeover episode, with special guest host BioTechniques’ Senior Digital Editor Abi Sawyer, takes a look at the results of Future Science Group’s (London, UK) survey for the scientific community on gender equality and parity in STEM. Abi’s guests on this episode are the Vice President of Epidemiology and Clinical Evidence at IQVIA (NC, USA), Dr Christina Mack; the Executive Director for the Pharmaceutical Research Computing Center at the University of Maryland Schoo...
Mar 05, 2021•40 min
3DMedNet International Women's Day: an interview with Lee-Bath Nelson by Taylor & Francis Group
Mar 02, 2021•9 min
This episode takes a look at the role the COVID-19 Genomics UK Consortium (COG-UK) has played sequencing SARS-CoV-2 and surveying for COVID-19. To do this I speak to two key members of the consortium; Steve Paterson, Professor of genetics at the University of Liverpool and lead for the wastewater working group of COG-UK; and Josh Quick, Future Leaders Fellow at the University of Birmingham and lead at the COG-UK Sequencing working group. Steve discusses some of the techniques required to detect ...
Feb 18, 2021•35 min
In the Zone: how do we decide a vaccine is effective? by Taylor & Francis Group
Feb 03, 2021•9 min
RT-PCR, antigen and antibody testing; each has its niche and each has a flaw. But what are the key differences between each of these tests and when what are the key things to consider when selecting the appropriate COVID-19 diagnostic for you? In this podcast, supported by Zymo Research, I speak to Senior Scientist in assay development Paolo Piati in order to answer this question. Whether you are a concerned citizen looking for the best test to take to inform your behavior, or a researcher aimin...
Jan 15, 2021•21 min
In this podcast, Juandem Agendia and Sarah Alexander (NCTC, UK) discuss bacteriophages, the function of the NCTC and the importance of depositing bacteriophages in the NCTC collection to improve accessibility and reproducibility in science.
Nov 09, 2020•26 min
OCTalks: Comprehensive Genomic Profiling by Taylor & Francis Group
Nov 09, 2020•19 min
OCTalks: the ethics of COVID-19 and cancer by Taylor & Francis Group
Nov 09, 2020•11 min
OCTalks: targeting FGFR2 in advanced cholangiocarcinoma by Taylor & Francis Group
Oct 21, 2020•10 min
The importance of data management: an interview with Xiaonan Tang by Taylor & Francis Group
Sep 21, 2020•11 min
Brendan Griffin (University College Cork, Ireland)discusses his work in early drug development in this interview with Bioanalysis Zone. Brendan talks about the most common challenges faced as well as key trends in the field of developability. For more content, visit www.bioanalysis-zone.com
Jul 03, 2020•6 min
In this Technique Blast – a new series that will provide short informative discussions about a specific technique – Digital Editor Tristan Free speaks to Joseph Pesek about high-performance liquid-chromatography and chromatographic separation technologies.
Jun 18, 2020•6 min
In the face of the COVID-19 pandemic, innovators are finding novel ways to apply 3D-printed solutions to assist the international response to coronavirus. From meeting PPE demands, to designing novel approaches to unique challenges, the additive community has not been short of opportunity for collaboration and corroboration with multidisciplinary teams exploring options for aiding crises from local to international capacities. In this podcast, in collaboration with Women in 3D Printing, we invit...
Jun 08, 2020•50 min
Integrating patient-relevant outcomes into clinical practice: an interview with Donna Messner by Taylor & Francis Group
Jun 05, 2020•28 min
NCTalks with Gavin Giovannoni: advancements in the treatment landscape for multiple sclerosis by Taylor & Francis Group
May 18, 2020•18 min
Comparing real-world and randomized controlled trial data: an interview with Michael Moran by Taylor & Francis Group
Apr 30, 2020•18 min
BioTechniques Digital Editor Tristan Free, speaks to Application Scientist Theresa Thompson and Strategy Director Jay Pasquantonio (both Phoseon Technology) about their UV LEDs. We cover the best wavelengths for disrupting nucleotides and proteins, the challenges associated with some of these wavelengths, and the promising potential of UV LEDs to disinfect inorganic surfaces of SARS-CoV-2. Theresa and Jay also detail the safety procedures required while using this technology and deliver a clear ...
Apr 24, 2020•30 min
Estimating the opportunity–cost-based cost–effectiveness threshold: a panel discussion by Taylor & Francis Group
Apr 22, 2020•18 min
In the first installment of this two-part episode with Donald Ingber, Founding Director of the Wyss Institute (MA, USA), we discuss his invention of organ-on-a-chip technology, how he is utilizing them in the fight against COVID-19 and the Wyss Institute's response to the pandemic. Donald touches on the performance of the much-discussed chloroquine in his lung-on-a-chip models. We also discuss the pros and cons of organ-on-a-chip technology verses organoids, exploring their use in combination, b...
Apr 14, 2020•33 min